11 Results for "

Staphylococcus spp

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "Staphylococcus spp" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-16911
CAS No.: 620175-39-5
Synonyms: API-1252; Debio 1452
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

AFN-1252 is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC90 values of ⩽0.015 μg/ml against diverse clinical isolates of S. aureus. AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith .
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Cat. No.: HY-P2148
CAS No.: 190673-58-6
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Inflammation/Immunology

P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans .
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Cat. No.: HY-105282
CAS No.: 110865-90-2
Purity:  95.87%
Synonyms: MM 45289; A 82846A
Eremomycin (MM 45289) is a potent glycopeptide antibiotic closely related to Vancomycin (HY-B0671). Eremomycin shows antibacterial activity in Staphylococcus spp. and Bacillus subtilis ATCC6633, with the MIC values of 0.03-1.6 μg/mL .
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Cat. No.: HY-125388
CAS No.: 160791-16-2
Martinomycin is an antibiotic, which inhibits Staphylococcus spp., Streptococcus spp. and Enterococcus spp., with MICs ranging from 0.06 to 0.5 μg/mL .
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Cat. No.: HY-114622
CAS No.: 1047981-31-6
Synonyms: API-1252 tosylate; Debio 1452 tosylate
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

AFN-1252 (API-1252) tosylate is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 tosylate exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 tosylate exhibits typical MIC90 values of 0.015 μg/ml against diverse clinical isolates of S. aureus. AFN-1252 tosylate is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith .
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Cat. No.: HY-105434
CAS No.: 108461-05-8
Target:  

Bacterial

Research Areas:  

Infection

CP-74667 is a quinolone antibacterial agent. CP-74667 shows high activity against Xanthomonas maltophilia (MIC50 = 1 μg/mL), Staphylococcus spp. (MIC50 = 0.06-0.12 μg/mL) and enterococci (MIC50 = 0.5-4 μg/mL) .
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Cat. No.: HY-N12178
CAS No.: 106803-22-9
Synonyms: A 83094A; Omomycin
16-Deethylindanomycin (A 83094A) is an antibiotic, which can be produced by Streptomyces setonii. 16-Deethylindanomycin exhibits antimicrobial activities against gram-positive bacteria Staphylococcus spp. and Streptococcus with MIC of 2-4 µg/mL. 16-Deethylindanomycin exhibits anticoccidial activity against Eimeria tenella .
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Cat. No.: HY-125042
CAS No.: 130756-15-9
Target:  

Bacterial

Research Areas:  

Infection

Sarothralin G is an antibacterial compound isolated from Hypericum japonicum Thunb. (Japanese spurfle). The structure of Sarothralin G contains phenolic and aromatic acid moieties and shows excellent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus, Bacillus subtilis and Nocardia spp., which is stronger than Sarothralen A, B and Saroaspidin A, B, C. Sarothralin G exhibits significant antibacterial potential.
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Cat. No.: HY-123508
CAS No.: 127967-03-7
Research Areas:  

Infection

PD 131628 is an antimicrobial agent and active PD 131112 metabolite. PD 131628 is two- to four-fold more active than Ciprofloxacin (HY-B0356), inhibiting all strains of Staphylococcus aureus and Streptococcus pneumoniae. PD 131628 is very active against Neisseria spp., Haemophilus influenzae and Moraxella catarrhalis, with MIC90s ranging from 0.004 to 0.008 mg/L .
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Cat. No.: HY-181686
Research Areas:  

Infection

Antibacterial agent 326 is a bactericide that inhibits the growth of various bacterial strains. Antibacterial agent 326 inhibits biofilm formation in Escherichia coli, disrupts bacterial cell membranes, induces oxidative stress and lipid peroxidation in Escherichia coli, increases ROS levels, and reduces GSH activity. Antibacterial agent 326 can be used in studies of bacterial infections, including those caused by Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, Listeria spp., Bacillus subtilis, Serratia marcescens, Salmonella enteritidis and Acinetobacter calcoaceticus .
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Cat. No.: HY-N21878
CAS No.: 474328-38-6
Muraymycin D2 is a peptidyl nucleoside natural product derived from Streptomyces spp., possessing competitive translocase I (MraY) inhibitory activity and antibacterial activity. Muraymycin D2 competitively binds to the nucleotide-binding pocket of the MraY substrate via its nucleoside moiety, and upon binding, induces a conformational change in MraY, blocking lipid I synthesis and inhibiting peptidoglycan biosynthesis. Muraymycin D2 exhibits a Ki of 7.6 nM against Bacillus subtilis and an IC50 of 0.39 nM against Staphylococcus aureus. Muraymycin D2 shows antibacterial activity against Escherichia coli and is capable of breaking persistence in chlamydial infection. Muraymycin D2 can be used for research on bacterial infection-related studies, such as chlamydial infection .
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