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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
TLK2
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "TLK2" in MCE Product Catalog:
Cat. No.: HY-162426
CAS No.: 3069333-33-8
UNC-CA2-103 is a TLK2 inhibitor with a human IC50 of 18 nM, and it exhibits high selectivity over TLK1 and the vast majority of other kinases. UNC-CA2-103 can be used in research related to breast cancer, glioblastoma and gastric cancer .
Cat. No.: HY-RS14571
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TLK2 Human Pre-designed siRNA Set A contains three designed siRNAs for TLK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18263
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Tlk2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tlk2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24742
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Tlk2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tlk2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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LSD1/TLK1-IN-1 is an orally active LSD1, TLK1, TLK2, TTK inhibitor with an LSD1 IC50 of 0.247 μM. LSD1/TLK1-IN-1 suppresses phosphorylation of Nek1 at T141 and Rad9 at S328, abrogates the TLK1>Nek1>ATR>Chk1 axis, protects H3K4me1/2 from demethylation, and does not affect LSD2, MAO-A, or MAO-B. LSD1/TLK1-IN-1 induces apoptosis, bypasses cell-cycle arrest, suppresses tumor growth, downregulates PD-L1 expression, enhances T-cell killing response, inhibits gastric cancer cell proliferation. LSD1/TLK1-IN-1 can be used for the research of prostate cancer and gastric cancer [2].
Cat. No.: HY-P702737
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: TLK2; tousled-like kinase 2; serine/threonine-protein kinase tousled-like 2; MGC44450; PKU ALPHA; serine/threonine kinase; PKU-ALPHA
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
