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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
TMR
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "TMR" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-D2270
CAS No.: 2764890-88-0
Cat. No.: HY-42984
CAS No.: 916753-62-3
Cat. No.: HY-D1704
CAS No.: 849464-08-0
Cat. No.: HY-D1672
CAS No.: 749247-49-2
Cat. No.: HY-136937
CAS No.: 2067339-51-7
Cat. No.: HY-D2966
CAS No.: 1928762-04-2
Cat. No.: HY-D1592
CAS No.: 937803-31-1
Cat. No.: HY-D2291
CAS No.: 2671036-80-7
Target:
Domaines de recherche:
BODIPY TMR amide NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
Cat. No.: HY-D2946
Synonyms: BC-TMR
Cat. No.: HY-D1593
CAS No.: 2923990-43-4
Cat. No.: HY-D1108
Cat. No.: HY-D2993
CAS No.: 1418275-35-0
Synonyms: BG-TMR
Target:
Domaines de recherche:
SNAP-TMR (BG-TMR) is a cell-permeable fluorescent dye used for visualizing SNAP fusion proteins and performing single-molecule imaging for motor movement analysis. SNAP-TMR covalently binds to the active site of the SNAP tag domain on fusion proteins, thereby reporting the presence, localization, or movement of the protein. The excitation wavelength of SNAP-TMR is 561 nm, and the maximum labeling efficiency reaches 80% .
Cat. No.: HY-D3418
Target:
Domaines de recherche:
BOD-Tz-TMR is a fluorescent probe used for nitric oxide (NO) detection and atherosclerotic plaque imaging.BOD-Tz-TMR has a detection limit of 31 nM for NO. BOD-Tz-TMR functions via Förster resonance energy transfer (FRET) and bioorthogonal reactions, in which the tetrazine linker quenches fluorescence through the energy transfer to dark state (ETDS) mechanism. The interaction of BOD-Tz-TMR with NO triggers a ratiometric shift in fluorescence from BODIPY (Ex/Em: 488 nm/512 nm, green channel) to TMR (Em: 592 nm, red channel). BOD-Tz-TMR labels macrophages through a bioorthogonal reaction with BCN, enabling its targeted accumulation at atherosclerotic plaque sites to detect endogenous NO associated with lesion progression. BOD-Tz-TMR can be used in studies related to atherosclerosis .
Cat. No.: HY-179839
CAS No.: 2260795-39-7
Target:
Domaines de recherche:
BODIPY TMR Lyso PA ester ammonium is a fluorescent lipid.
Cat. No.: HY-DY1107
CAS No.: 2764890-88-0
Solvent and concentration: DMSO: 5 mM
Cat. No.: HY-D3416
Synonyms: TAMRA-2,4-dinitroaniline
Target:
Domaines de recherche:
TMR-DN (TAMRA-2,4-dinitroaniline) is a fluorescent probe for RNA imaging that consists of a covalently coupled fluorophore (5-carboxy tetramethylrhodamine (TMR)) and quencher (dinitroaniline (DN)). The Kd value of TMR-DN with SRB-2 is 35 nM, and its Kd value with RhoBAST is approximately 30 nM. TMR-DN has a contact quenching function and forms a non-fluorescent intramolecular ground-state dimer in the free state; the excitation/emission wavelengths of the free probe are Ex/Em = 557/579 nm, those of the complex formed by binding to SRB-2 are Ex/Em = 561/587 nm, and those of the probe bound to the DNB aptamer are Ex/Em = 555/582 nm. TMR-DN reduces non-specific binding to genomic nucleic acids via negatively charged carboxyl-functionalized aromatic rings. Fluorescence dequenching occurs when TMR-DN specifically binds to SRB-2, RhoBAST or the DNB aptamer, among which the binding of RhoBAST requires Mg 2+ for proper folding .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
