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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
TREx
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "TREx" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-160785
CAS No.: 2756594-27-9
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TREX1-IN-1 is a TREX1 inhibitor with an IC50 value for hTREX1 less than 0.1 μM .
Cat. No.: HY-160786
CAS No.: 2588445-13-8
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TREX1-IN-3 (Compound 95) is an inhibitor of both TREX1 and TREX2, with an IC50 for TREX1 of less than 0.1 μM, an IC50 for TREX2 of less than 1 μM, and an EC50 for HCT116 cells of less than 1 μM. TREX1-IN-3 can be used in cancer research .
Cat. No.: HY-160786A
CAS No.: 2588445-14-9
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TREX1-IN-4 (Compound 96) is an inhibitor of both TREX1 and TREX2, with an IC50 for TREX1 of less than 0.1 μM, an IC50 for TREX2 of less than 1 μM, and an EC50 for HCT116 cells ranging from 0.1 to 10 μM. TREX1-IN-4 can be used in cancer research .
Cat. No.: HY-RS15008
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TREX1 Human Pre-designed siRNA Set A contains three designed siRNAs for TREX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15009
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TREX2 Human Pre-designed siRNA Set A contains three designed siRNAs for TREX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17776
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Trex1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trex1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22876
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Trex2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trex2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24243
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Trex1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trex1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29390
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Trex2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trex2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184953
CAS No.: 3099598-25-8
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Anticancer agent 345 is a heterobifunctional anticancer compound that exhibits weak antiproliferative activity against both ERα-overexpressing and non-overexpressing T-Rex 293 cells . Anticancer agent 345 can be used in cancer-related research .
Cat. No.: HY-184502
CAS No.: 3034295-80-9
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DDO-88109 is a STING inhibitor with a Kd value of 317 nM for hSTING and 0.625 μM for mSTING. DDO-88109 competitively occupies the CDN-binding pocket of STING, thereby maintaining STING in an inactive state. It inhibits cGAS-STING signaling—including STING translocation from the endoplasmic reticulum to the Golgi apparatus, STING oligomerization, and the phosphorylation of IRF3, p65, TBK1, and STING—and attenuates the production of inflammatory cytokines and tissue inflammation in mouse models of TREX1-deficiency-driven autoinflammation and cisplatin (HY-17394)-induced acute kidney injury. DDO-88109 is suitable for research on inflammatory diseases, autoimmune disorders, and acute kidney injury driven by the cGAS-STING pathway .
Cat. No.: HY-184960
CAS No.: 3099599-58-0
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Anticancer agent 352 is a heterobifunctional anticancer compound. Anticancer agent 352 exhibits only weak antiproliferative activity against both ERα-overexpressing and non-overexpressing T-Rex 293 cells induced by Doxorubicin (HY-15142A). Anticancer agent 352 can be used in breast cancer-related research .
Cat. No.: HY-P87119
Synonyms: 3' 5' exonuclease TREx1 antibody; 3' repair exonuclease 1 antibody; AGS1 antibody; AGS5 antibody; CRV antibody; Deoxyribonuclease III, dnaQ/mutD (E. coli) like antibody; DKFZp434J0310 antibody; DNase III antibody; DRN3 antibody; HERNS antibody; 3' 5' exonuclease TREx1 antibody; 3' repair exonuclease 1 antibody; AGS1 antibody; AGS5 antibody; CRV antibody; Deoxyribonuclease III, dnaQ/mutD (E. coli) like antibody; DKFZp434J0310 antibody; DNase III antibody; DRN3 antibody; HERNS antibody; Three prime repair exonuclease 1 antibody; TREx1 antibody;
Cat. No.: HY-184900
CAS No.: 3099598-43-0
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Anticancer agent 341 (Compound III-163) is a non-ERα-dependent cytotoxic agent with its GI50 for MCF cells is 0.05-0.5 μΜ. Anticancer agent 341 exhibits GI50 for T-Rex 293 cells regardless of whether Doxycycline (Dox) (HY-N0565) is added of all < 0.05 μΜ. Anticancer agent 341 can be used in breast cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
