TREX1/2-IN-1
TREX1/2-IN-1 is a potent dual TREX1 and TREX2 inhibitor with IC50 values of < 0.1 μΜ and < 1 μΜ, respectively. TREX1/2-IN-1 inhibits TREX1/2 exonuclease activity, promotes cGAS/STING pathway activation, and ultimately induces IFN production, thereby reactivating the innate immune system to recognize and attack tumor cells. TREX1/2-IN-1 can be used for cancer research.
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- CAS No.: 2588445-13-8
- Formule: C24H19ClN6O4
- Masse moléculaire:490.90
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
Description
IC50 & Target
[1]|
TREX1 < 0.1 μM (IC50) |
TREX2 < 1 μM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2588445-13-8
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Masse moléculaire 490.90
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Formule C24H19ClN6O4
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SMILES
CN(C1=NC(C(NC2=CON=C2)=O)=C(C(N1C)=O)O)[C@@H](C3=C(C=CC=C3)Cl)C4=CC(C#N)=CC=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TREX1/2-IN-1 Related Classifications
HY-160786 Related Classifications
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