TREX1-IN-3
TREX1-IN-3 (Compound 95) is an inhibitor of both TREX1 and TREX2, with an IC50 for TREX1 of less than 0.1 μM, an IC50 for TREX2 of less than 1 μM, and an EC50 for HCT116 cells of less than 1 μM. TREX1-IN-3 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2588445-13-8
- Formula: C24H19ClN6O4
- Molecular Weight:490.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 2588445-13-8
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Molecular Weight 490.90
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Formula C24H19ClN6O4
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SMILES
CN(C1=NC(C(NC2=CON=C2)=O)=C(C(N1C)=O)O)[C@@H](C3=C(C=CC=C3)Cl)C4=CC(C#N)=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)