10 Results for "

VP16

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "VP16" in MCE Product Catalog:

186
186 Publications Verification
Cat. No.: HY-13629
CAS No.: 33419-42-0
Purity:  99.94%
Synonyms: VP-16; VP-16-213
Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy .
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2
2 Cited Publications
Cat. No.: HY-19350
CAS No.: 537034-17-6
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

BML-210 is a potent HDAC inhibitor. BML-210 can inhibit the HDAC4-VP16-driven reporter signal with an apparent IC50 of ∼5 µM. BML-210 has a specific disruptive effect on the HDAC4:MEF2 interaction. BML-210 causes an increase in the G0/G1 phase. BML-210 induces apoptosis and displays antitumour activities in orthotopic mammary tumours in mice .
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1
1 Cited Publications
Cat. No.: HY-13629R
CAS No.: 33419-42-0
Synonyms: VP-16 (Standard); VP-16-213 (Standard)
Etoposide (Standard) is the analytical standard of Etoposide. This product is intended for research and analytical applications. Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy .
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Cat. No.: HY-401424
CAS No.: 61791-12-6
Synonyms: Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil
Cremophor EL-36 is a non-ionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). For example, Cremophor EL-36 can enhance the intracellular influx of Etoposide (HY-13629) without affecting drug efflux, and can dose-dependently increase the accumulation of VP-16 in lung adenocarcinoma cells (such as PC-14 and A549), significantly enhancing its cytotoxic effect .
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Cat. No.: HY-W744243
Synonyms: VP-16-d4; VP-16-213-d4
Etoposide-d4 (VP-16-d4; VP-16-213-d4) is the deuterium labeled Etoposide (HY-13629). Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy .
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Cat. No.: HY-13629S
Synonyms: VP-16-d3; VP-16-213-d3
Etoposide-d3 (VP-16-d3) is the deuterium labeled Etoposide (HY-13629). Etoposide (VP-16) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy .
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Cat. No.: HY-13629S1
Synonyms: VP-16-13C,d3; VP-16-213-13C,d3
Etoposide- 13C,d3 is the 13C- and deuterium labeled Etoposide. Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy .
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Cat. No.: HY-174788
Target:  

mRNA

Research Areas:  

Others

HHV-1 UL48 mRNA encodes the UL48 protein of human herpesvirus 1 (HHV-1). UL48 is a tanscriptional activator of immediate-early (IE) gene products (alpha genes). It acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1.
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Cat. No.: HY-402601
Target:  

ROR

Research Areas:  

Others

Desethyl-SID 7969543 is an isoquinolinone analog of SID 7969543 (HY-107404) and a selective SF-1 (NR5A1) inhibitor. Desethyl-SID 7969543 shows no activity against RORA, VP16 and LRH-1, and exhibits no cytotoxicity at concentrations close to its SF-1 IC50 value .
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Cat. No.: HY-P811022
Synonyms: HCF1, HFC1, HCFC1, Host cell factor 1, HCF, HCF-1, C1 factor, CFF, VCAF, VP16 accessory protein

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

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