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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
WNK Kinase
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "WNK Kinase" in MCE Product Catalog:
21
21 Cited Publications
Target:
Research Areas:
WNK463 is an orally bioavailable pan-With-No-Lysine (K) (WNK)-kinase inhibitor with IC50s of 5 nM, 1 nM, 6 nM, and 9 nM for WNK1, WNK2, WNK3, and WNK4, respectively .
4
4 Cited Publications
Target:
Research Areas:
WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.
Target:
Research Areas:
WNK-IN-1 (compound 7) is a ATP noncompetitive With-No-Lysine (WNK) kinase inhibitor (IC50=95 nM). WNK-IN-1 can be used to regulate cardiovascular homeostasis .
Cat. No.: HY-E70806
Target:
Research Areas:
WNK1 is a WNK kinase that is involved in embryonic angiogenesis and tumor-induced angiogenesis. Biotin-WNK1 Recombinant Human Active Protein Kinase is obtained by expressing WNK1 proteins and is biotinylated .
Cat. No.: HY-E70807
Target:
Research Areas:
WNK3 is a WNK kinase that associates with and activate SPAK/OSR1 by phosphorylation of its T-loop at Thr233 and Thr185. Biotin-WNK3 Recombinant Human Active Protein Kinase is obtained by expressing WNK3 proteins and is biotinylated .
Cat. No.: HY-101959A
CAS No.: 118409-60-2
Target:
Research Areas:
Tyrphostin 47 is a nonspecific inhibitor of WNK1. Tyrphostin 47 is a protein tyrosine kinase inhibitor. Tyrphostin 47 inhibits smooth-muscle cell proliferation
Cat. No.: HY-111286
CAS No.: 853298-47-2
Target:
Research Areas:
WNK-IN-2 is an ATP-competitive WNK kinase inhibitor with low kinase selectivity .
Cat. No.: HY-189224
CAS No.: 2728520-90-7
Target:
Research Areas:
WNK2-IN-1 is a WNK2 inhibitor. WNK2-IN-1 inhibits the kinase activity of recombinant WNK2 in a dose-dependent manner, and simultaneously partially inhibits WNK3 and WNK4. WNK2-IN-1 modulates WNK2-SPAK downstream signaling by inhibiting WNK2-mediated SPAK phosphorylation, and further suppresses the proinflammatory transcriptional response induced by IL1β. WNK2-IN-1 can be used in studies related to the WNK2 signaling pathway and osteoarthritis .
Cat. No.: HY-P703360
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: WNK4; WNK Lysine Deficient Protein Kinase 4; PRKWNK4; Serine/Threonine-Protein Kinase WNK4; Protein Kinase Lysine-Deficient 4; Protein Kinase With No Lysine 4; Protein Kinase, Lysine Deficient 4; PHA2B
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705584
Synonyms: WNK4; WNK Lysine Deficient Protein Kinase 4; PRKWNK4; Serine/Threonine-Protein Kinase WNK4; Protein Kinase Lysine-Deficient 4; Protein Kinase With No Lysine 4; Protein Kinase, Lysine Deficient 4; PHA2B
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705597
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: WNK3; WNK Lysine Deficient Protein Kinase 3; PRKWNK3; Serine/Threonine-Protein Kinase WNK3; Protein Kinase With No Lysine 3; Prieto X-Linked Mental Retardation Syndrome; Protein Kinase, Lysine Deficient 3; Protein Kinase Lysine-Deficient 3; KIAA1566; MRXS
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706115
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: WNK2; WNK Lysine Deficient Protein Kinase 2; SDCCAG43; PRKWNK2; Serologically Defined Colon Cancer Antigen 43; NY-CO-43; KIAA1760; Serine/Threonine-Protein Kinase WNK2; Protein Kinase Lysine-Deficient 2; Protein Kinase With No Lysine 2; Antigen NY-CO-43;
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703072
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: WNK1; WNK Lysine Deficient Protein Kinase 1; PRKWNK1; HSN2; PPP1R167; HSAN2; Protein Phosphatase 1, Regulatory Subunit 167; Serine/Threonine-Protein Kinase WNK1; Protein Kinase With No Lysine 1; Erythrocyte 65 KDa Protein; KDP; P65; Non-Specific Serine/Th
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P82468
Synonyms: WNK1; HSN2; KDP; KIAA0344; PRKWNK1; Serine/threonine-protein Kinase WNK1; Erythrocyte 65 kDa protein; p65; Kinase deficient protein; Protein Kinase lysine-deficient 1; Protein Kinase with no lysine 1; hWNK1
Cat. No.: HY-P706114
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: WNK1; WNK Lysine Deficient Protein Kinase 1; PRKWNK1; HSN2; PPP1R167; HSAN2; Protein Phosphatase 1, Regulatory Subunit 167; Serine/Threonine-Protein Kinase WNK1; Protein Kinase With No Lysine 1; Erythrocyte 65 KDa Protein; KDP; P65; Non-Specific Serine/Th
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
