2123489-30-3
2123489-30-3
Chemical Structure
WNK-IN-11
- CAS No.: 2123489-30-3
- Formula:C21H21Cl2N5OS
- Molecular Weight:462.40
IUPAC Name: (5-chloro-2-(2-(methylamino)thiazol-4-yl)pyridin-4-yl)(4-(4-chlorobenzyl)piperazin-1-yl)methanone
InChIKey: MVXAYIXYYOVALX-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=CSC(NC)=N2)=NC=C1Cl)N3CCN(CC4=CC=C(Cl)C=C4)CC3
Biological Activity: WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.
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WNK-IN-11 | 99.71% | WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1. | ||||||||||||||||||||
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WNK-IN-11-d3 | 99.84% | WNK-IN-11-d3 is an orally active, selective and potent With-No-Lysine (WNK) kinase inhibitor. WNK-IN-11-d3 is effective at regulating cardiovascular homeostasis. | ||||||||||||||||||||
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Keywords
