Tyrphostin 47
Tyrphostin 47 is a nonspecific inhibitor of WNK1. Tyrphostin 47 is a protein tyrosine kinase inhibitor. Tyrphostin 47 inhibits smooth-muscle cell proliferation
For research use only. We do not sell to patients.
- CAS No.: 118409-60-2
- Formula: C10H8N2O2S
- Molecular Weight:220.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
3 μM
Compound: 125, RG-50864 (AG-213)
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Inhibition of EGFR in human A431 cells
Inhibition of EGFR in human A431 cells
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[PMID: 1479375] |
Chemical Information
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CAS No. 118409-60-2
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Molecular Weight 220.25
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Formula C10H8N2O2S
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SMILES
S=C(N)/C(C#N)=C/C1=CC=C(O)C(O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Erfinanda L, et al. Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation. Sci Transl Med. 2022 Dec 7;14(674):eabg8577. [Content Brief]
[2]. Gottsauner-Wolf M, et al. Influence of local delivery of the protein tyrosine kinase receptor inhibitor tyrphostin-47 on smooth-muscle cell proliferation in a rat carotid balloon-injury model. Am Heart J. 1997 Mar;133(3):329-34. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tyrphostin 47 Related Classifications
HY-101959A Related Classifications
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