1 Result for "

XP-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "XP-5" in MCE Product Catalog:

Cat. No.: HY-115885
CAS No.: 2760511-91-7
Target:  

HDAC

Research Areas:  

Inflammation/Immunology Cancer

XP5 is a potent, orally active HDAC6 inhibitor with an IC50 of 31 nM. XP5 displays high antiproliferative activity against various cancer cell lines including the HDACi-resistant YCC3/7 gastric cancer cells (IC50=0.16-2.31 μM). XP5 enhances antitumor immunity when combined with a PD-L1 inhibitor in melanoma .
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