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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
abnormal cell proliferation diseases
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "abnormal cell proliferation diseases" in MCE Product Catalog:
6
6 Cited Publications
Cat. No.: HY-N0430A
CAS No.: 1198398-71-8
Cat. No.: HY-P990552A
Target:
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BRD4 Inhibitor-10 (Compound II-25) is a potent BRD4-BD1 inhibitor with an IC50 of 8 nM. BRD4 Inhibitor-10 can be used to study diseases caused by abnormal or excessive cell proliferation, such as cancer .
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CGP 53716 is a potent protein tyrosine kinase inhibitor. CGP 53716 has selective activity of platelet-derived growth factor (PDGF) receptor. CGP 53716 can be used in the study of disease induced by abnormal cell proliferation induced by PDGF receptor activation .
Cat. No.: HY-162534
CAS No.: 3034764-38-7
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GSPT1 degrader-5 is a GSPT1 molecular glue degrader that recruits cereblon (CRBN), with a DC50 of 20 nM. GSPT1 degrader-5 induces GSPT1 protein degradation via the ubiquitin-proteasome pathway. GSPT1 degrader-5 can be used in breast cancer-related research .
Cat. No.: HY-162533
CAS No.: 3034764-32-1
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GSPT1 degrader-4 is a GSPT1 molecular glue degrader that recruits cereblon (CRBN), with a DC50 of 25.4 nM. GSPT1 degrader-4 inhibits the proliferation of cancer cells. GSPT1 degrader-4 is applicable to breast cancer-related research .
Cat. No.: HY-162535
CAS No.: 3034764-41-2
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GSPT1 degrader-6 is a GSPT1 molecular glue degrader that recruits cereblon (CRBN), with a DC50 of 13 nM. GSPT1 degrader-6 induces GSPT1 protein degradation via the ubiquitin-proteasome pathway. GSPT1 degrader-6 can be used in breast cancer-related research .
Cat. No.: HY-146033
CAS No.: 331851-78-6
HPV18-IN-1 (Compound H1) is a potent inhibitor of HPV18. HPV18-IN-1 prevents cervical cancer cells from premature cell procession and abnormal proliferation. HPV18-IN-1 supresses E7-Rb-E2F cellular pathway and DNA methylation. HPV18-IN-1 has the potential for the research of cancer diseases .
Cat. No.: HY-117051
CAS No.: 1046490-67-8
STA-2842 is an inhibitor of heat shock protein HSP90 with potential to inhibit autosomal dominant polycystic kidney disease (ADPKD). ADPKD is caused by inherited mutations in the PKD1 or PKD2 genes that abnormally activate multiple signaling proteins and pathways that regulate cell proliferation. STA-2842 can significantly reduce initial renal cyst formation and kidney growth in mice, and slow disease progression in mice with existing cysts.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
