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Results for "

alertness

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

4

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2364
    Arecoline
    5 Publications Verification

    		 mAChR nAChR Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Arecoline, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline also can induce oxidative stress .
    Arecoline
  • HY-B0489
    Arecoline hydrobromide
    5 Publications Verification

    methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide

    		 mAChR nAChR Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .
    Arecoline hydrobromide
  • HY-17549
    Adrafinil

    CRL 40028

    		 Adrenergic Receptor Neurological Disease
    Adrafinil (CRL 40028) is an orally active vigilance promoting agent. Adrafinil enhances central noradrenergic transmission, improves spontaneous activity, exploratory behavior, discriminative learning ability and response motivation, but impairs visuospatial working memory. Adrafinil antagonizes Prazosin (HY-B0193)-induced hypoactivity and hypothermia, exerts anticonvulsant effects, and induces sustained enhancement of high-frequency electrocortical activity. Adrafinil can be used for research on decreased alertness and specific cognitive deficits .
    Adrafinil
  • HY-B0489R
    Arecoline hydrobromide (Standard)

    methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide (Standard)

    		 Reference Standards mAChR nAChR Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Arecoline hydrobromide (Standard) is the analytical standard of Arecoline hydrobromide. This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .
    Arecoline hydrobromide (Standard)
  • HY-B0489A
    Arecoline hydrochloride

    		mAChR nAChR Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Arecoline hydrochloride, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrochloride exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrochloride also can induce oxidative stress .
    Arecoline hydrochloride
  • HY-19036
    SDZ NVI 085

    		Adrenergic Receptor Neurological Disease
    SDZ NVI 085 is a compound with CNS stimulatory effects, primarily through the α1-adrenoceptor subtype, with anti-cataplexy and anti-stroke activities. SDZ NVI 085 also has a significant alertness effect and can be used to study other types of excessive sleepiness .
    SDZ NVI 085
  • HY-W011235R
    Norfluoxetine hydrochloride (Standard)

    		Reference Standards 5-HT Receptor Calcium Channel Drug Metabolite Cardiovascular Disease Neurological Disease
    Arecoline (hydrobromide) (Standard) is the analytical standard of Arecoline (hydrobromide). This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .
    Norfluoxetine hydrochloride (Standard)
  • HY-W739837
    Arecoline-d5 hydrobromide

    		Isotope-Labeled Compounds mAChR nAChR Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Arecoline-d5 hydrobromide is the deuterium labeled Arecoline hydrobromide (HY-B0489). Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .
    Arecoline-d5 hydrobromide
  • HY-182763
    EGFR/BRAFV600E-IN-7

    		EGFR Raf Caspase Apoptosis Bcl-2 Family Cancer
    EGFR/BRAFV600E-IN-7 is a dual EGFR and BRAF V600E kinase inhibitor with human IC50 values of 0.12 μM, 0.80 μM, 1.20 μM for EGFR and 0.05 μM, 0.22 μM, 0.78 μM for BRAF V600E.EGFR/BRAFV600E-IN-7 interacts with key ATP-binding site residues of EGFR and BRAF V600E, including hydrogen bonding with EGFR Met769 and BRAF V600E Cys532.EGFR/BRAFV600E-IN-7 induces apoptosis via caspase-3/8/9 activation, modulates Bax and Bcl-2 expression, scavenges free radicals, and exhibits antiproliferative activity against human cancer cell lines.EGFR/BRAFV600E-IN-7 displays drug-likeness with no PAINS/Brenk structural alerts per in silico predictions.EGFR/BRAFV600E-IN-7 can be used for the research of colon cancer, pancreatic cancer, lung cancer, breast cancer .
    EGFR/BRAFV600E-IN-7

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