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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
563 Results for "
and class D
" in MedChemExpress (MCE) Product Catalog:
Products (563)
563 Results for "and class D" in MCE Product Catalog:
54
54 Publications Verification
CB-5083 is a first-in-class, potent, selective, and orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC50 of 11 nM .
6
Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii .
5
5 Cited Publications
Target:
Research Areas:
O-304 is a first-in-class, orally available pan-AMPK activator, which increases AMPK activity by suppressing the dephosphorylation of pAMPK. O-304 exhibits a great potential as a agent to treat type 2 diabetes (T2D) and associated cardiovascular complications .
3
3 Cited Publications
Target:
Research Areas:
LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. LEI-401 modulates emotional behavior in mice .
1
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Levosulpiride (RV-12309) is the (S)-enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic agent of the benzamide class.
1
1 Cited Publications
Cat. No.: HY-B0150S
CAS No.: 347841-88-7
Synonyms: Niacinamide-d4; Nicotinic acid amide-d4
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1
1
1 Cited Publications
Cat. No.: HY-P70601
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCGRT; Major Histocompatibility Complex class I-Like Fc Receptor; Fc Gamma Receptor and Transporter; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 6; Neonatal Fc Receptor; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 5; FcRn; Neonatal Fragment Crystallizable Fc Receptor FcRn; IgG Fc Fragment Receptor Transporter Alpha Chain; Immunoglobulin Receptor, Intestinal, Heavy Chain; IgG Receptor FcRn Large Subunit P51; Neonatal Fc-Receptor For Ig; FcgammaRn; FCRN Alpha-Chain; Heavy Chain Of The Major Histocompatibility Complex class I-Like Fc Receptor; FcRn Alpha Chain; Transmembrane Alpha Chain Of The Neonatal Receptor; Alpha-Chain; Fc Fragment Of IgG, Receptor, Transporter, Alpha; FCRN; Fc Fragment Of IgG Receptor and Transporter; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr Beta Chain
Species:
Human
Source:
HEK293
Synonyms: 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C
Category:
Human Gut Microbiota Metabolites Metabolic Disease Endogenous metabolite Disease Research Fields Steroids
Target:
Target:
Cat. No.: HY-P4193
CAS No.: 181272-91-3
Target:
Research Areas:
Cat. No.: HY-13666S
CAS No.: 1246819-64-6
Synonyms: (-)-Tetramisole-d5 hydrochloride
Cat. No.: HY-W047710
CAS No.: 21193-75-9
Target:
Research Areas:
BLI-489 hydrate is a Beta-lactamase inhibitor. BLI-489 hydrate is an antibacterial adjuvant that significantly enhances the antibacterial efficacy of β-lactam antibiotics. BLI-489 hydrate blocks the hydrolytic activity of the enzyme by forming a stable intermediate in serine Beta-lactamase, or by coordinating with the binuclear Zn 2+ through an oxygen atom in metallo-Beta-lactamase. BLI-489 hydrate can be used for research on bacterial infections .
Cat. No.: HY-112251GL
CAS No.: 1224606-06-7
Cat. No.: HY-132824
CAS No.: 1842399-68-1
Synonyms: VNRX-7145
Target:
Research Areas:
Ledaborbactam etzadroxil (VNRX-7145) is an orally active Ambler class A, C, and D β-lactamase enzymes inhibitor .
Cat. No.: HY-W008216S
CAS No.: 1015855-78-3
Synonyms: Hydroxy Dimetridazole-d3
Cat. No.: HY-B0176AS
CAS No.: 1330180-66-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
