15 Results for "

anemia of chronic disease

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "anemia of chronic disease" in MCE Product Catalog:

20
20 Publications Verification
Cat. No.: HY-17608
CAS No.: 960539-70-2
Synonyms: GSK1278863
Research Areas:  

Cardiovascular Disease

Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor being developed for the treatment of anemia associated with chronic kidney disease.
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9
9 Cited Publications
Cat. No.: HY-101277
CAS No.: 1000025-07-9
Purity:  99.83%
Synonyms: PG-1016548; AKB-6548
Research Areas:  

Cardiovascular Disease

Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor . Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo .
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6
6 Cited Publications
Cat. No.: HY-N1428C
CAS No.: 3522-50-7
Synonyms: Iron(III) citrate; Zerenex
Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research .
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Cat. No.: HY-47030
CAS No.: 2338-05-8
Ferric citrate hydrate, an orally active iron supplement, is an efficacious phosphate binder. Ferric citrate hydrate can be used for iron deficiency anemia and chronic kidney disease (CKD) research .
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Cat. No.: HY-P3761
CAS No.: 147821-01-0
Target:  

Caspase

Research Areas:  

Inflammation/Immunology

Ac-Tyr-Val-Lys-Asp-aldehyde is a reversible caspase-1 inhibitor. Ac-Tyr-Val-Lys-Asp-aldehyde increases GATA1 levels by inhibiting caspase-1 and promotes erythroid differentiation. can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia .
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Cat. No.: HY-125288
CAS No.: 2247168-13-2
Target:  

Ferroportin

Research Areas:  

Metabolic Disease

DS42450411 is an orally active hepcidin production inhibitor with an IC50 of 32 nM. DS42450411 in an acute inflammatory mouse model induced by IL-6, DS42450411 significantly reduces serum hepcidin levels. DS42450411 can be used for studying iron homeostasis .
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Cat. No.: HY-17608R
CAS No.: 960539-70-2
Synonyms: GSK1278863 (Standard)
Daprodustat (Standard) is the analytical standard of Daprodustat. This product is intended for research and analytical applications. Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor being developed for the treatment of anemia associated with chronic kidney disease.
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Cat. No.: HY-101277S1
Synonyms: PG-1016548-13C6; AKB-6548-13C6
Vadadustat- 13C6 (PG-1016548- 13C6) is 13C labeled Vadadustat. Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor . Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo .
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Cat. No.: HY-P990965
CAS No.: 2761347-19-5

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Efparepoetin alfa is an EPO receptor agonist. Efparepoetin alfa can be used in the research of anemia caused by chronic kidney disease .
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Cat. No.: HY-170915
CAS No.: 1842340-93-5
Research Areas:  

Others

DDO-3055 is an orally active PHD2 inhibitor that can be used in the research of anemia associated with chronic kidney disease .
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Cat. No.: HY-163148
CAS No.: 2924181-77-9
Research Areas:  

Cardiovascular Disease

PHD-IN-3 (Compound 15) is an orally active PHD inhibitor. PHD-IN-3 can be used in the study of anemia associated with chronic kidney disease .
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Cat. No.: HY-124133
CAS No.: 1238689-36-5
Research Areas:  

Cardiovascular Disease

JNJ-42905343 is an orally active and highly selective prolyl hydroxylase (PHD1/2/3) inhibitor with pKI values of 8.07, 7.48 and 7.27 for PHD1, PHD2 and PHD3, respectively. JNJ-42905343 is promising for research of functional iron deficiency (FID) and anemia of chronic disease (ACD) .
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Cat. No.: HY-P991881
KY1070 is a fully human anti-BMP6 antibody with a Kd of 0.00014 μM against the human BMP6. It exhibits high specificity for BMP6, showing no cross-reactivity with other members of the BMP family, and effectively inhibits BMP6-induced BMP receptor heterodimerization and hepcidin expression. KY1070 modulates Ferroportin expression on erythroid progenitor cells and accelerates erythropoiesis. In rodent anemia models, KY1070 reduces the required dose of erythropoietin (EPO) when used in combination with EPO and enhances the responsiveness of mice with chronic kidney disease (CKD)-associated anemia to EPO treatment. KY1070 is applicable for research on anemia of chronic disease [1] [2].
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Cat. No.: HY-180560
CAS No.: 2924181-95-1
Research Areas:  

Inflammation/Immunology

PHD-IN-5 (ISM4808) is an orally active PHD inhibitor that can be used for studying anemia in chronic kidney disease .
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Cat. No.: HY-101277R
CAS No.: 1000025-07-9
Synonyms: PG-1016548 (Standard); AKB-6548 (Standard)
Vadadustat (Standard) is the analytical standard of Vadadustat (HY-101277). This product is intended for research and analytical applications. Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor . Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo .
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