2. Metabolic Enzyme/Protease
  3. HIF/HIF Prolyl-Hydroxylase
  4. DDO-3055

DDO-3055 is an orally active PHD2 inhibitor that can be used in the research of anemia associated with chronic kidney disease.

For research use only. We do not sell to patients.

DDO-3055

DDO-3055 Chemical Structure

CAS No. : 1842340-93-5

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
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Based on 1 publication(s) in Google Scholar

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Description

DDO-3055 is an orally active PHD2 inhibitor that can be used in the research of anemia associated with chronic kidney disease[1].

Clinical Trial
Molecular Weight

360.75

Formula

C17H13ClN2O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(OCC#CC2=CC(O)=C(C(NCC(O)=O)=O)N=C2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (277.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7720 mL 13.8600 mL 27.7200 mL
5 mM 0.5544 mL 2.7720 mL 5.5440 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.64%

SDS (252 KB)

COA (244 KB) HNMR (272 KB) LCMS (325 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7720 mL 13.8600 mL 27.7200 mL 69.3001 mL
5 mM 0.5544 mL 2.7720 mL 5.5440 mL 13.8600 mL
10 mM 0.2772 mL 1.3860 mL 2.7720 mL 6.9300 mL
15 mM 0.1848 mL 0.9240 mL 1.8480 mL 4.6200 mL
20 mM 0.1386 mL 0.6930 mL 1.3860 mL 3.4650 mL
25 mM 0.1109 mL 0.5544 mL 1.1088 mL 2.7720 mL
30 mM 0.0924 mL 0.4620 mL 0.9240 mL 2.3100 mL
40 mM 0.0693 mL 0.3465 mL 0.6930 mL 1.7325 mL
50 mM 0.0554 mL 0.2772 mL 0.5544 mL 1.3860 mL
60 mM 0.0462 mL 0.2310 mL 0.4620 mL 1.1550 mL
80 mM 0.0347 mL 0.1733 mL 0.3465 mL 0.8663 mL
100 mM 0.0277 mL 0.1386 mL 0.2772 mL 0.6930 mL
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DDO-3055 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DDO-30551842340-93-5DDO3055DDO 3055HIF/HIF Prolyl-HydroxylaseHypoxia-inducible factorsHIFsHIF-PHInhibitorinhibitorinhibit

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