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Results for "

anti-neuropathic

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

4

Natural
Products

1

Isotope-Labeled Compounds

Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-N0021
    Verbascoside
    10+ Cited Publications

    Acteoside; Kusaginin; TJC160

    		 PKC Apoptosis Bacterial HSV Neurological Disease Inflammation/Immunology Cancer
    Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.
    Verbascoside
  • HY-N5142
    α-Terpineol
    2 Publications Verification

    		 Environmental Pollutants Antibiotic Bacterial Fungal AMPK NF-κB Infection Neurological Disease Metabolic Disease Inflammation/Immunology
    α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .
    α-Terpineol
  • HY-106856
    Dimiracetam

    NT-11624

    		 iGluR Cancer
    Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201)-induced neuropathy in cold stimulation rat models .
    Dimiracetam
  • HY-125821
    Sigma-1 receptor antagonist 1

    		Sigma Receptor Neurological Disease
    Sigma‑1 receptor antagonist 1 (compound 137) is a potent and selective sigma-1 receptor (σ1R) antagonist, with a high binding affinity to σ1R receptor (Ki = 1.06 nM). Sigma‑1 receptor antagonist 1 exhibits antineuropathic pain activity and acts as a promising agent for the treatment of neuropathic pain .
    Sigma-1 receptor antagonist 1
  • HY-N0021R
    Verbascoside (Standard)

    Acteoside (Standard); Kusaginin (Standard); TJC160 (Standard)

    		 Reference Standards PKC Apoptosis Bacterial HSV Neurological Disease Inflammation/Immunology Cancer
    Verbascoside (Standard) is the analytical standard of Verbascoside. This product is intended for research and analytical applications. Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.
    Verbascoside (Standard)
  • HY-W028263
    6-Hydroxyflavanone

    		COX Opioid Receptor GABA Receptor Lipoxygenase Metabolic Disease Inflammation/Immunology
    6-Hydroxyflavanone is a compound that can be isolated from the Muntingia calabura leaves. 6-Hydroxyflavanone targets cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors that has anti-inflammatory and anti-neuropathic pain potential. 6-Hydroxyflavanone can be used for the research of diabetes .
    6-Hydroxyflavanone
  • HY-146383
    H3R antagonist 2

    		Histamine Receptor Cholinesterase (ChE) Monoamine Oxidase Neurological Disease
    H3R antagonist 2 (Compound 23) is a multitarget histamine H3 receptor (H3R) antagonist with a Ki of 170 nM for hH3R . H3R antagonist 2 shows inhibitory effects with IC50 values of 180, 880 and 775 nM for acetylcholinesterase, butyrylcholinesterase and human monoamine oxidase B (hMAO B), respectively. H3R antagonist 2 shows favorable anti-neuropathic pain and memory-enhancing effects. H3R can across BBB .
    H3R antagonist 2
  • HY-163207
    sEH/HDAC6-IN-1

    		Epoxide Hydrolase HDAC Neurological Disease
    sEH/HDAC6-IN-1 (compound M9) is a selective, orally active dual inhibitor for sEH and HDAC6, with IC50s of 2 nM, 0.72 nM and 5 nM, for human sEH, murine sEH and HDAC6, respectively. sEH/HDAC6-IN-1 reveals analgesic and anti-inflammatory effects .
    sEH/HDAC6-IN-1
  • HY-N5142S1
    α-Terpineol-d6

    		Bacterial Isotope-Labeled Compounds Infection
    α-Terpineol-d6 is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .
    α-Terpineol-d6
  • HY-106856R
    Dimiracetam (Standard)

    NT-11624 (Standard)

    		 iGluR Reference Standards Cancer
    Dimiracetam (Standard) (NT-11624 (Standard)) is the analytical standard of Dimiracetam (HY-106856). This product is intended for research and analytical applications. Dimiracetam is an orally active compound, with anti-neuropathic activity. Dimiracetam inhibits hypersensitivity and neurological alterations, and inhibits Sorafenib (HY-10201)-induced neuropathy in cold stimulation rat models .
    Dimiracetam (Standard)

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