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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
91 Results for "
antihyperglycemic
" in MedChemExpress (MCE) Product Catalog:
Products (91)
91 Results for "antihyperglycemic" in MCE Product Catalog:
197
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Rosiglitazone (BRL 49653) is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM), with blood-brain barrier permeability. Rosiglitazone is an TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone can be used in the research of obesity and diabetes, senescence, ovarian cancer .
197
197 Publications Verification
Cat. No.: HY-17386A
CAS No.: 302543-62-0
Synonyms: BRL 49653 hydrochloride
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Rosiglitazone (BRL 49653) hydrochloride is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone hydrochloride is a TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone hydrochloride can be used in the research of obesity and diabetes, senescence, ovarian cancer .
194
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Rosiglitazone (BRL 49653) potassium is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone potassium is a TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone potassium can be used in the research of obesity and diabetes, senescence, ovarian cancer .
15
Category:
Polysaccharides Microorganisms Anti-aging Metabolic Disease Disease Research Fields Saccharides
Target:
7
Category:
Alkaloids Piperidine Alkaloids Metabolic Disease Plants Moraceae Disease Research Fields Morus alba Linn.
Target:
7
7 Cited Publications
Synonyms: Duvoglustat hydrochloride
Category:
Commelinaceae Commelina communis L. Metabolic Disease Plants Disease Research Fields Saccharides Monosaccharides
Target:
5
5 Cited Publications
Cat. No.: HY-N0669
CAS No.: 57817-89-7
Category:
Trifolium hybridum L. Terpenoids Diterpenoids Plants Compositae Disease Research Fields Sweeteners Cancer Food Research
Target:
5
5 Cited Publications
Synonyms: LAF237; NVP-LAF 237
Target:
Research Areas:
Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
5
Category:
Microorganisms Monophenols Ketones, Aldehydes, Acids Manihot esculenta Crantz Phenols Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology
Target:
4
4 Cited Publications
Target:
Research Areas:
GSK-3β inhibitor 1 (compound 3a) inhibits GSK-3β with an IC50 of 4.19 nM. GSK-3β inhibitor 1 demonstrates high antidiabetic efficacy in obese Streptozotocin (HY-13753)-treated rats .
3
Target:
3
3 Cited Publications
Cat. No.: HY-N0472
CAS No.: 60976-49-0
Category:
Phyllanthus urinaria Linn. Metabolic Disease Other Phenylpropanoids Plants Phenols Polyphenols Euphorbiaceae Phenylpropanoids Disease Research Fields Inflammation/Immunology
Target:
3
3 Cited Publications
Cat. No.: HY-16482
CAS No.: 250694-07-6
1
1 Cited Publications
Cat. No.: HY-N2168
CAS No.: 69251-96-3
Synonyms: (+)-Pinoresinol 4-O-β-D-glucopyranoside
Synonyms: meso-Nordihydroguaiaretic acid; meso-NDGA
Target:
Target:
Target:
Research Areas:
AZD1656 is a potent, selective and orally active glucokinase activator with an EC50 of 60 nM. AZD1656 has the potential for type 2 diabetes research .
Cat. No.: HY-P10271
Synonyms: NNC0090-2746; MAR709; RO6811135
Target:
Research Areas:
Research Areas:
Biguanide is an orally active antihyperglycemic agent. Biguanide inhibits mitochondrial ATP production, activates the LKB1-AMPK signaling pathway, and damages the energy homeostasis. Biguanide enhances insulin-receptor activation and downstream signaling. Biguanide exhibits potential in ameliorating the type 2 diabetes and the insulin-associated cancers.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
