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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
bacterial metabolic activity
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "bacterial metabolic activity" in MCE Product Catalog:
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Omeprazole sulfide (Ufiprazole) is a metabolic degradation product of Omeprazole (HY-B0113). Omeprazole sulfide acts as a modulator of AhR. Omeprazole sulfide in cells with low CYP3A4 expression, functions as an AhR antagonist; however, in cells with high CYP3A4 expression, it is rapidly metabolized to Omeprazole, thereby acting as an AhR agonist. Omeprazole sulfide exhibits antibacterial activity when conjugated with silver nanoparticles (AgNPs). Omeprazole sulfide can be used in research on acid suppression and bacterial infections .
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Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections .
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Cat. No.: HY-W015954
CAS No.: 24347-58-8
Cat. No.: HY-D2919
CAS No.: 2177287-88-4
Cat. No.: HY-137006
CAS No.: 57360-69-7
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MTT Formazan is a purple water-insoluble product formed by the reduction of yellow soluble MTT by succinate dehydrogenase in the mitochondria of viable cells. The amount of MTT Formazan produced is proportional to cellular metabolic activity, and it can serve as an indicator for evaluating cell viability and proliferation. MTT Formazan exhibits solvent-dependent solubility properties, and its absorbance value can be measured by spectrophotometry to reflect cellular status. MTT Formazan also supports the assessment of cell viability in bacterial MTT assays. MTT Formazan can be used in photoacoustic microscopy to enhance the imaging effect of viable cells, especially in applications in the fields of three-dimensional cell culture and tissue engineering .
Cat. No.: HY-19487
CAS No.: 1381289-58-2
Ribocil is a selective inhibitor targeting the bacterial FMN riboswitch, regulating the bacterial riboflavin riboswitch. Ribocil competitively binds to the FMN binding site, mimicking the natural ligand FMN to induce conformational changes in the riboswitch, inhibiting ribB gene expression, reducing riboflavin synthesis, and thus inhibiting bacterial growth. Ribocil strongly inhibits GFP expression (EC50=0.3 μM). Ribocil exhibits in vivo antibacterial activity in a mouse model and can be used to study antibacterial drugs related to drug-resistant bacterial infections and bacterial riboflavin metabolic pathways[1][2].
Cat. No.: HY-W037825
CAS No.: 2236-60-4
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Infection Neurological Disease Inflammation/Immunology Cancer
Pterin is a pteridine with antibacterial activity. Pterin binds to the Fe 2+ active site via its carbonyl group, reducing the oxygen activation energy barrier in hydroxylases. Pterin participates in metabolic redox processes. Pterin can be used in research related to cancer, vitiligo, bacterial infections, phenylketonuria, Parkinson's disease, schizophrenia and depression .
Cat. No.: HY-N7921
CAS No.: 1006683-97-1
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Cat. No.: HY-W015954R
CAS No.: 24347-58-8
Cat. No.: HY-N8519
CAS No.: 104542-46-3
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Cat. No.: HY-173190
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Antibacterial agent 271 is an antibacterial agent with significant inhibition against Escherichia coli (MIC: 2.2 μM). Antibacterial agent 271 reduces metabolic activity by disrupting the integrity of bacterial membranes. Antibacterial agent 271 binds to DNA grooves to inhibit replication and induces accumulation of reactive oxygen species (ROS) , ultimately leading to bacterial death. Antibacterial agent 271 shows significant potential in combating bacterial infections .
Cat. No.: HY-173238
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Antibacterial Agent 273 (Compound 15e) is a membrane-targeting antimicrobial agent that disrupts bacterial cell membranes, exhibiting a MIC of 4 μg/mL against Staphylococcus aureus. By compromising membrane integrity, it induces leakage of intracellular nucleic acids and proteins, suppresses bacterial metabolic activity, and triggers the accumulation of reactive oxygen species (ROS). Antibacterial Agent 273 is suitable for research on infections caused by Staphylococcus aureus .
Cat. No.: HY-W158160
CAS No.: 144254-93-3
AGS1286 (sodium 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate) is an organosulfur compound that serves as a model for investigating the impact of sulfur-containing compounds on enzymatic activities and metabolic pathways. Additionally, it has been employed to explore the regulatory effects of these compounds on bacterial growth and gene expression.
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Dichlorophen (Standard) is the analytical standard of Dichlorophen (HY-12638). This product is intended for research and analytical applications. Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections .
Cat. No.: HY-161279
Research Areas:
Antibiofilm agent-5 (compound 6c) is a multitargeting antibacterial agent with potent antibiofilm activity. Antibiofilm agent-5 could induce metabolic dysfunction by deactivating lactate dehydrogenase and promote the accumulation of reactive oxygen species to decrease the reduced glutathione and ultimately cause oxidative damage in bacteria. Antibiofilm agent-5 can be used for the research of refractory biofilm-intensified bacterial infections .
Cat. No.: HY-184296
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CPO 4 is a DNA-targeting antibacterial agent. CPO 4 intercalates into DNA to form a CPO 4-DNA complex, thereby blocking DNA replication. CPO 4 disrupts the metabolic activity of bacteria. CPO 4 induces intracellular protein leakage in bacteria. CPO 4 can be used for the research of drug-resistant bacterial infections .
Cat. No.: HY-B0389F1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
