638-95-9
638-95-9
Chemical Structure
α-Amyrin
- CAS. Nr.: 638-95-9
- Formula:C30H50O
- Molecular Weight:426.72
IUPAC Name: (3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a,6b,8a,11,12,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-ol
InChIKey: FSLPMRQHCOLESF-SFMCKYFRSA-N
SMILES: C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CC[C@H]([C@@H]4C)C)C)=CC[C@]1([H])[C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])CC2)C)C
Biological Activity: α-Amyrin is a pentacyclic triterpenoid compound with oral activity. α-Amyrin activates the ERK and GSK-3β signaling pathways. α-Amyrin can inhibit cancer cells proliferation and induce apoptosis. α-Amyrin shows anti-bacterial and anti-inflammation activity. α-Amyrin can reduce blood glucose level. α-Amyrin can be used for the researches of cancer, infection, inflammation, metabolic disease and neurological disease, such as breast cancer, Streptococcus oralis infection, skin inflammation and diabetes[1][2][3][4][5][6][7].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
α-Amyrin | 99.99% | α-Amyrin is a pentacyclic triterpenoid compound with oral activity. α-Amyrin activates the ERK and GSK-3β signaling pathways. α-Amyrin can inhibit cancer cells proliferation and induce apoptosis. α-Amyrin shows anti-bacterial and anti-inflammation activity. α-Amyrin can reduce blood glucose level. α-Amyrin can be used for the researches of cancer, infection, inflammation, metabolic disease and neurological disease, such as breast cancer, Streptococcus oralis infection, skin inflammation and diabetes. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
α-Amyrin (Standard) | ≥98% | α-Amyrin (Standard) is a pentacyclic triterpenoid compound with oral activity. α-Amyrin (Standard) activates the ERK and GSK-3β signaling pathways. α-Amyrin (Standard) can inhibit cancer cells proliferation and induce apoptosis. α-Amyrin (Standard) shows anti-bacterial and anti-inflammation activity. α-Amyrin (Standard) can reduce blood glucose level. α-Amyrin (Standard) can be used for the researches of cancer, infection, inflammation, metabolic disease and neurological disease, such as breast cancer, Streptococcus oralis infection, skin inflammation and diabetes. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ursolic acid | 99.02% | Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Uvaol | 99.20% | Uvaol, a triterpene present in olives and virgin olive oil, possesses anti-inflammatory properties and antioxidant effects. Uvaol is an orally active inducer of apoptosis in astroglioma cells. Uvaol also has anti-cancer activities. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Sophoradiol | Sophoradiol is a triterpenoid compound that can be extracted from Abrus Precatorius. Sophoradiol is an orally effective anti-tuberculosis agent. Sophoradiol has inhibitory activity against various strains of Mycobacterium tuberculosis. Sophoradiol has good biocompatibility. Sophoradiol can be used in the research of tuberculosis. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Epi-β-amyrin | Epi-β-amyrin is a chemical component that can be extracted from Euphorbia pulcherrima. Epi-β-amyrin is a steroid compound. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Triptohypol E | Triptohypol E is a triterpenoid compound and nitric oxide production inhibitor that can be isolated from the leaves of Rhododendron dauricum L. Triptohypol E inhibits nitric oxide production in LPS-stimulated macrophages in a dose-dependent manner. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
β-Amyrin (Standard) | ≥98% | β-Amyrin shows effectively counteract amyloid β (Aβ)-induced impairment of long-term potentiation (LTP). β-Amyrin is a promising candidate for Alzheimer's disease (AD) research. β-Amyrin exhibits anti-inflammatory effects, protective activity against pulmonary fibrosis, and notable antibacterial capabilities. β-Amyrin is an orally active natural triterpenoid compound. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Dulcioic acid | Dulcioic acid (compound 19) is a product isolated from Tripterygium wilfordii Hook f. Dulcioic acid shows a significant inhibitory effect on cytokine production. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3-Epiursolic Acid | 99.86% | 3-Epiursolic Acid is a natural triterpenoid and a competitive inhibitor of Cathepsin L, with an IC50 of 6.5 μM and a Ki of 19.5 μM. 3-Epiursolic Acid acts through competitive inhibition of Cathepsin L. 3-Epiursolic Acid can be used in research on Cathepsin L inhibitors and tumor-associated proteases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Multiflorenol | Multiflorenol is a triterpene alcohol that can be obtained from the bark of Gelonium multiflorum A. Juss.. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ursolic aldehyde | Ursolic aldehyde is a triterpenoid isolated from plants. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Giacoman-Martínez A, et al. α-Amyrin induces GLUT4 translocation mediated by AMPK and PPARδ/γ in C2C12 myoblasts. Can J Physiol Pharmacol. 2021 Sep;99(9):935-942. [Content Brief]
- [2]. Prabhakar P, et al. α-Amyrin attenuates high fructose diet-induced metabolic syndrome in rats. Appl Physiol Nutr Metab. 2017 Jan;42(1):23-32. [Content Brief]
- [3]. Park SJ, et al. Amyrin attenuates scopolamine-induced cognitive impairment in mice. Biol Pharm Bull. 2014;37(7):1207-13. [Content Brief]
- [4]. Singh AB, et al. Antihyperglycaemic activity of alpha-amyrin acetate in rats and db/db mice. Nat Prod Res. 2009;23(9):876-82. [Content Brief]
- [5]. Medeiros R, et al. Mechanisms underlying the inhibitory actions of the pentacyclic triterpene alpha-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate. Eur J Pharmacol. 2007 Mar 22;559(2-3):227-35. [Content Brief]
- [6]. Kevine Kamga Silihe, Purification of α-amyrin-acetate and phenylpropanoïd compounds from Ficus umbellata Vahl (Moraceae) stem bark and evaluation of their anti-breast cancer potential, South African Journal of Botany, 177 (2025) 445-456.
- [7]. Díaz-Ruiz G, et al. Growth inhibition of Streptococcus from the oral cavity by α-amyrin esters. Molecules. 2012 Oct 25;17(11):12603-11. [Content Brief]
