Antihyperglycaemic activity of alpha-amyrin acetate in rats and db/db mice

  • Nat Prod Res. 2009;23(9):876-82. doi: 10.1080/14786410802420416.
A B Singh  1 ,  D K Yadav ,  R Maurya ,  A K Srivastava
Affiliations
  • 1. Division of Biochemistry, Central Drug Research Institute, Lucknow, India.
PMID: 19488928 DOI: 10.1080/14786410802420416
Abstract

The article reveals the antihyperglycaemic activity of the alpha-amyrin acetate (alpha-AA) isolated from the aerial roots of the Ficus bengalensis in normal and diabetic rats and model of type-2 diabetes, i.e. db/db mice. The oral administration of alpha-AA significantly improved the diabetic condition in streptozotocin-induced diabetic rats and in diabetic db/db mice at 50 mg kg(-1) dose level.

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