15 Results for "

bacterial plasma membrane

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "bacterial plasma membrane" in MCE Product Catalog:

2
2 Cited Publications
製品番号: HY-P5712
CAS 番号: 113-73-5
別名: Gramicidin soviet
研究分野:  

Infection

Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic that selectively targets bacterial cell membranes and has anticancer activity. Gramicidin S also exerts antibacterial activity by destroying membrane integrity and interfering with membrane protein function. Gramicidin S inserts into the phospholipid bilayer through hydrophobic amino acid residues, specifically binds to negatively charged membrane lipids and disrupts membrane structure, thereby inhibiting cell division and cell wall synthesis, and ultimately causing bacterial death. Gramicidin S also inhibits ion channels, with IC50s of 41 μM, 24 μM, and 3 μM for Na +/K +-ATPase, tobacco leaf plasma membrane Mg 2+/K +-ATPase, and rat heart plasma membrane Ca 2+-ATPase, respectively .
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製品番号: HY-D0259
CAS 番号: 16423-68-0
別名: Erythrosin extra bluish; Tetraiodofluorescein disodium
研究分野:  

Infection

Erythrosine B (Erythrosin extra bluish; Tetraiodofluorescein) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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製品番号: HY-156004
CAS 番号: 2399497-60-8
純度:  99.62%
Target:  

Bacterial

研究分野:  

Others

Ziapin 2 is a membrane potential modulator and an intracellular membrane photoactuator. Ziapin 2 binds to the bacterial plasma membrane, and upon embedding into the lipid bilayer, undergoes trans-cis isomerization under 470 nm light irradiation, which triggers membrane potential hyperpolarization and induces the opening of ion channels on bacterial cell membranes. Through interactions with lipids, Ziapin 2 increases the overall flexibility of the lipid bilayer. Ziapin 2 can form photosensitive transmembrane dimers to trigger cellular signal transduction. Ziapin 2 is applicable to the research and regulation of bacterial electrical signal transduction and the regulation of membrane physical properties .
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製品番号: HY-107864
CAS 番号: 15905-32-5
純度:  99.07%
別名: Erythrosin extra bluish free acid; Tetraiodofluorescein
研究分野:  

Infection

Erythrosine B free acid​ (Erythrosin extra bluish free acid; Tetraiodofluorescein) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B free acid serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B free acid exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B free acid is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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製品番号: HY-P5640
CAS 番号: 179264-81-4
Target:  

Bacterial Parasite

研究分野:  

Infection

Tritrpticin is a porcine-derived antimicrobial peptide with properties such as membrane disruption and hemolysis. Tritrpticin disrupts the cell membranes of bacteria, fungi and Jurkat T cell leukemia cells and induces their death. Tritrpticin also enhances the efficacy of Metronidazole (HY-B0318) against *Trichomonas vaginalis*, reduces plasma endotoxin and inflammatory cytokine levels, restricts bacterial growth in blood and visceral tissues, decreases the mortality rate of septic shock in rats and enhances the therapeutic effect of ertapenem. Tritrpticin exhibits selective cytotoxicity against Jurkat T cell leukemia cells, while showing low toxicity to normal peripheral blood mononuclear cells and red blood cells, and can serve as a template for antimicrobial peptide design. Tritrpticin can be applied to research related to bacterial infections, fungal infections, trichomoniasis, septic shock and leukemia .
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製品番号: HY-178476
CAS 番号: 3096122-10-7
研究分野:  

Infection

Anti-MRSA agent 36 (Compound III13) is an antibacterial agent with strong anti MRSA activity (MIC = 1 μg/mL). Anti-MRSA agent 36 targets phosphatidylglycerol (PG) on bacterial membranes, disrupting membrane integrity, leading to DNA leakage and increased ROS. Anti-MRSA agent 36 has advantages such as low cytotoxicity, low hemolysis, difficulty in inducing drug resistance, and good plasma stability. Anti-MRSA agent 36 can be used for the study of skin abscess and systemic infection models .
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製品番号: HY-P11251
Target:  

Bacterial

研究分野:  

Infection

RI-18 is an antimicrobial peptide. RI-18 exhibits high affinity for bacterial plasma membranes, inducing rapid membrane permeabilization and rupture. RI-18 exhibits potent antimicrobial activity against bacteria in planktonic and biofilmforms .
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製品番号: HY-P5553
Target:  

Bacterial

研究分野:  

Infection

cPcAMP1/26 is an antimicrobial peptide. cPcAMP1/26 effectively kills A.hydrophila and S. aureus. cPcAMP1/26 induces depolarization of the bacterial plasma membrane, and increases intracellular ROS levels .
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製品番号: HY-161988
CAS 番号: 3055131-42-2
Target:  

Bacterial

Antimicrobial agent-34 (compound 4h) is an antibacterial agent (MIC = 1–4 μg/mL), with a clogP value of 9.14. Antimicrobial agent-34 has good plasma stability (HC50 of 131.1 μg/mL) and good membrane selectivity (HC50/MIC is 65.6), with rapid sterilization capability. Antimicrobial agent-34 destroys the integrity of bacterial cell membranes, induces an increase in intracellular reactive oxygen species, and leaks protein and DNA, ultimately leading to bacterial death. Antimicrobial agent-34 demonstrates significant in vivo antibacterial potency in a mouse sepsis model infected with Staphylococcus aureus ATCC43300 .
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製品番号: HY-D0259R
CAS 番号: 16423-68-0
別名: Erythrosin extra bluish (Standard); Tetraiodofluorescein disodium (Standard)
研究分野:  

Infection

Erythrosine B (Standard) (Erythrosin extra bluish (Standard); Tetraiodofluorescein disodium (Standard)) is the analytical standard of Erythrosine B (HY-D0259). This product is intended for research and analytical applications. Erythrosine B (Erythrosin extra bluish; Tetraiodofluorescein) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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製品番号: HY-P11897
Target:  

Bacterial

研究分野:  

Infection

RBWH11 is a synthetic antimicrobial peptide. RBWH11 disrupts the integrity of bacterial plasma membranes, induces changes in membrane permeability and causes bacterial death. RBWH11 can eliminate established bacterial biofilms. RBWH11 exhibits broad-spectrum antimicrobial activity against Gram-negative and Gram-positive ESKAPE pathogens, including multidrug-resistant strains. RBWH11 can be used for the research of multidrug-resistant bacterial infections .
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製品番号: HY-180125
研究分野:  

Infection

Antibacterial agent 307 is an antibacterial agent. Antibacterial agent 307 shows MICs of 1-4 μg/mL against Gram-positive bacteria, moderate activity against Gram-negative bacteria, low hemolytic toxicity, and excellent plasma stability. Antibacterial agent 307 compromises bacterial membrane integrity via increased permeability and depolarization, induces endogenous ROS accumulation, causes cytoplasmic protein and nucleic acid leakage, and drives rapid bacterial cell death. Antibacterial agent 307 can be used for the research of bacterial infection .
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製品番号: HY-180125A
研究分野:  

Infection

Antibacterial agent 307 hydrochloride is an antibacterial agent. Antibacterial agent 307 hydrochloride shows MICs of 1-4 μg/mL against Gram-positive bacteria, moderate activity against Gram-negative bacteria, low hemolytic toxicity, and excellent plasma stability. Antibacterial agent 307 hydrochloride compromises bacterial membrane integrity via increased permeability and depolarization, induces endogenous ROS accumulation, causes cytoplasmic protein and nucleic acid leakage, and drives rapid bacterial cell death. Antibacterial agent 307 hydrochloride can be used for the research of bacterial infection .
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製品番号: HY-107864A
CAS 番号: 12227-78-0
別名: Erythrosin extra bluish aluminum; Tetraiodofluorescein aluminum
研究分野:  

Infection

Erythrosine B aluminum​ (Erythrosin extra bluish aluminum; Tetraiodofluorescein aluminum) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B aluminum serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B aluminum exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B aluminum is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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製品番号: HY-107864R
CAS 番号: 15905-32-5
別名: Erythrosin extra bluish free acid (Standard); Tetraiodofluorescein (Standard)
研究分野:  

Infection

Erythrosine B free acid (Standard) (Erythrosin extra bluish free acid (Standard); Tetraiodofluorescein (Standard)) is the analytical standard of Erythrosine B free acid (HY-107864). This product is intended for research and analytical applications. Erythrosine B free acid​ (Erythrosin extra bluish free acid; Tetraiodofluorescein) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B free acid serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B free acid exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B free acid is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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