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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
cerebral infarct volume
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "cerebral infarct volume" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: Chuanxiongzine; Tetramethylpyrazine
11
11 Publications Verification
Cat. No.: HY-N0935
CAS No.: 76494-51-4
Synonyms: Chuanxiongzine hydrochloride; Tetramethylpyrazine hydrochloride
4
4 Cited Publications
Cat. No.: HY-N1910
CAS No.: 20784-60-5
3
3 Cited Publications
Target:
Research Areas:
NBI-31772 is a non-selective IGFBP inhibitor (Ki=47 nM). NBI-31772 has neuroprotective effects and reduces infarct volume during cerebral ischemia. NBI-31772 can also restore or enhance proteoglycan synthesis in osteoarticular chondrocytes. In addition, NBI-31772 also increases the effect of IGF3 on zebrafish oocyte maturation .
2
2 Cited Publications
Cat. No.: HY-N0745
CAS No.: 94596-28-8
Category:
Natural Products Dicerothamnus rhinocerotis Plants Umbelliferae Disease Research Fields Inflammation/Immunology
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2
Target:
Cat. No.: HY-P5883
CAS No.: 2126166-03-6
Synonyms: tatM2NX
Target:
Research Areas:
Cat. No.: HY-N2125
CAS No.: 174972-80-6
Category:
Synonyms: U 74006F free base
Research Areas:
Tirilazad (U 74006F free base) is a neuroprotective agent. Tirilazad can also bind tightly to the main protease of the COVID-19 virus and exert anti-SARS-CoV-2 activity. Tirilazad scavenges hydroxyl and lipid peroxyl free radicals and maintains the levels of endogenous antioxidants. Tirilazad reduces cerebral infarct volume and improves neurobehavioral scores in animal models of focal ischemia. Tirilazad can be used in research related to ischemic stroke and subarachnoid hemorrhage .
Synonyms: LOE-908
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Research Areas:
Pinokalant is a broad-spectrum and non-selectivecation channel inhibitor. Pinokalant significantly reduces cortical infarct volume. Pinokalant o improves the metabolic and electrophysiologic status of the ischemic penumbra. Pinokalant reduces lesion size on magnetic resonance images in the acute phase following middle cerebral artery occlusion in rats. Pinokalant has the potential for the research of stroke. Pinokalant also shows anti-SARS-CoV-2 activity .
Synonyms: Chuanxiongzine (Standard); Tetramethylpyrazine (Standard)
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Research Areas:
Sipasterol (5α-Androstane-3β,5,6β-triol) is a neuroprotectant. Sipasterol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. Sipasterol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo .
Cat. No.: HY-100458
CAS No.: 2185855-51-8
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Research Areas:
SCR-4026 is a neuroprotective agent with blood-brain barrier penetration ability. SCR-4026 exerts neuroprotective effects by disrupting the interaction between neuronal nNOS and PSD9, with an IC50 of 6.3 μM. SCR-4026 alleviates N-methyl-D-aspartate (NMDA)-induced excitotoxic damage in primary cortical neurons, and also protects neurons in the oxygen-glucose deprivation (OGD) model. SCR-4026 can reduce the cerebral infarct volume in the rat middle cerebral artery occlusion (MCAO) reperfusion model. SCR-4026 can be used for the study of stroke .
Cat. No.: HY-110135R
CAS No.: 374620-70-9
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Research Areas:
NBI-31772 (Standard) is the analytical standard of NBI-31772. This product is intended for research and analytical applications. NBI-31772 is a non-selective IGFBP inhibitor (Ki=47 nM). NBI-31772 has neuroprotective effects and reduces infarct volume during cerebral ischemia. NBI-31772 can also restore or enhance proteoglycan synthesis in osteoarticular chondrocytes. In addition, NBI-31772 also increases the effect of IGF3 on zebrafish oocyte maturation .
Cat. No.: HY-132280R
CAS No.: 110101-66-1
Synonyms: U 74006F free base (Standard)
Research Areas:
Tirilazad (U 74006F free base) Standard is the analytical standard of Tirilazad (HY-132280). This product is intended for research and analytical applications. Tirilazad (U 74006F free base) is a neuroprotective agent. Tirilazad can also bind tightly to the main protease of the COVID-19 virus and exert anti-SARS-CoV-2 activity. Tirilazad scavenges hydroxyl and lipid peroxyl free radicals and maintains the levels of endogenous antioxidants. Tirilazad reduces cerebral infarct volume and improves neurobehavioral scores in animal models of focal ischemia. Tirilazad can be used in research related to ischemic stroke and subarachnoid hemorrhage .
Synonyms: α-N-Acetyl-L-glutamine (Standard); N2-Acetylglutamine (Standard)
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Cat. No.: HY-N2125R
CAS No.: 174972-80-6
Category:
Cat. No.: HY-W269032
CAS No.: 3598-68-3
Research Areas:
Lig4-4 is an orally active and selective TREK-1 inhibitor, with an IC50 of 2.06 μM in rats. Lig4-4 improves neuronal viability, reduces cell apoptosis by upregulating cleaved-caspase-3 and downregulating Bcl-2, and decreases infarct volume. Lig4-4 exerts a neuroprotective effect against cerebral ischemia injury. Lig4-4 can be used in studies related to cerebral ischemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
