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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
circular RNA
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "circular RNA" in MCE Product Catalog:
3
Cat. No.: HY-153081
Purity: ≥90.0%
Target:
Research Areas:
The eGFP circRNA will express green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. The eGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence with an emission peak at 509 nm. The eGFP circRNA is therefore ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.
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trans-ccc_R08 (Compound 1-B) is a cccDNA inhibitor with anti-HBV activity, with an IC50 of 0.14 μM for HBeAg and an IC50 of 0.08 μM for HBsAg in in vitro assays. trans-ccc_R08 inhibits covalently closed circular DNA (cccDNA). trans-ccc_R08 is applicable to research related to hepatitis B virus infection .
LNP Lipid-3 is an ionizable lipid that can be used to synthesize lipid nanoparticles. LNP Lipid-3 is applicable for mRNA delivery .
Cat. No.: HY-153082
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Firefly Luciferase circRNA will express a luciferase protein, originally isolated from the Photinus pyralis (Firefly). Firefly Luciferase circRNA is ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.
Cat. No.: HY-16680
CAS No.: 840529-13-7
Synonyms: Helioxanthin analogue 8-1
Helioxanthin 8-1(Helioxanthin analogue 8-1) is an anti-HBV agent. Helioxanthin 8-1 exhibits anti-hepatitis B virus activity in both in vitro human hepatitis B virus models and animal models. Helioxanthin 8-1 inhibits the synthesis of duck hepatitis B virus (DHBV) DNA, covalently closed circular DNA, RNA and proteins, thereby blocking DHBV replication. Helioxanthin 8-1 shows higher cytotoxicity in virus-induced cells than in non-induced cells. Helioxanthin 8-1 can be used in studies related to hepatitis B virus infection .
Cat. No.: HY-148781
CAS No.: 2413192-92-2
HBV-IN-30 (ex44), a flavone derivative, is a potent covalently closed circular DNA (cccDNA) inhibitor. cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-30 has the potential for the research of HBV infection .
Cat. No.: HY-144045
CAS No.: 2712529-19-4
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HBV-IN-14 is a potent inhibitor of covalently closed circular DNA (cccDNA). cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-14 is a pyridinopyrimidinones compound. HBV-IN-14 has the potential for the research of HBV infection (extracted from patent WO2021190502A1, compound 5) .
Cat. No.: HY-144046
CAS No.: 2413192-50-2
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HBV-IN-15 is a potent inhibitor of covalently closed circular DNA (cccDNA). cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-15 is a flavone derivative. HBV-IN-16 has the potential for the research of HBV infection (extracted from patent WO2020052774A1, compound 2) .
Cat. No.: HY-144047
CAS No.: 2355225-38-4
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HBV-IN-16 is a potent inhibitor of covalently closed circular DNA (cccDNA). cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-16 is a quinoline derivative. HBV-IN-16 has the potential for the research of HBV infection (extracted from patent WO2019121357A1, compound 1) .
Cat. No.: HY-185975
Scarless CD19 CAR circular RNA (CVB3) is a circular RNA that uses CVB3 IRES to mediate scarless expression of the CD19 chimeric antigen receptor (CAR) for CAR-T cell research. This circular RNA features a scarless circularization design, eliminating the need for a linker or adapter sequence between the 5′ and 3′ ends, and achieving efficient circularization and expression without the need for optimized UTR elements.
Cat. No.: HY-148780
CAS No.: 2413192-59-1
HBV-IN-29 (ex8), a flavone derivative, is a potent covalently closed circular DNA (cccDNA) inhibitor. cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-29 has the potential for the research of HBV infection .
Cat. No.: HY-P3103
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Cat. No.: HY-172332
CAS No.: 3097638-09-7
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H1L1A1B3 is an ionizable cationic lipid used in the formation of lipid nanoparticles (LNPs) for the delivery of circular RNA (circRNA). H1L1A1B3-LNPs demonstrates a fourfold increase in circRNA transfection efficiency in lung cancer cells over ALC-0315 (HY-138170). H1L1A1B3 can activate the NF-κB/IRF immune pathways .
Cat. No.: HY-P3103A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
