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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
costimulation
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "costimulation" in MCE Product Catalog:
2
2 Cited Publications
Synonyms: CTLA4lg; BMS-188667
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2
2 Cited Publications
Synonyms: CTLA4lg (powder); BMS-188667 (powder); Orencia
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Synonyms: BMS 224818; LEA 29Y
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Cat. No.: HY-P99605
CAS No.: 2218515-90-1
Synonyms: PRS 343
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Cat. No.: HY-179648
CAS No.: 1240857-57-1
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CD28-IN-2 is a selective CD28-B7 interaction (IC50: 22.4 μM) inhibitor that binds directly to CD28, with a Kd value of 24.1 μM. CD28-IN-2 inhibits CD28-driven immune activation and blocks T cell costimulation. CD28-IN-2 can be used for the study of antitumor immunity and immune-related disorders .
Cat. No.: HY-181507
CAS No.: 850550-70-8
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CD28-IN-3 is a CD28 inhibitor with an IC50 of 7.80 μM and a Kd of 52.45 μM. CD28-IN-3 selectively blocks the CD28-B7 interaction, thereby inhibiting CD28-mediated costimulation. CD28-IN-3 suppresses the production of proinflammatory cytokines IFN-γ, IL-2 and TNF-α. CD28-IN-3 can be used in the research of checkpoint-resistant cancers .
Cat. No.: HY-P991827
Cat. No.: HY-P992062
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Cat. No.: HY-P991921
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
