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Results for "

dilactone

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

4

Peptides

10

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17411
    Limonin
    10+ Cited Publications

    Limonoic acid 3,19:16,17 dilactone

    		 HIV Apoptosis Endogenous Metabolite Cytochrome P450 P-glycoprotein Infection Cancer
    Limonin inhibits HIV-1 with an EC50 of 60.0 μM. Limonin induces human colon adenocarcinoma cells apoptosis with an IC50 of 54.74 μM. Limonin has antiviral and antitumor activities .
    Limonin
  • HY-W000800
    cis,cis-Muconic acid

    		Bacterial Infection
    cis,cis-Muconic acid is a dicarboxylic acid produced by Saccharomyces cerevisiae. cis,cis-Muconic acid shows pH-dependent toxicity against Saccharomyces cerevisiae CEN.PK113-7D. cis,cis-Muconic acid can be used as intermediate for the production of various plastics and polymers .
    cis,cis-Muconic acid
  • HY-119906
    Conglobatin

    FW-04-806

    		 HSP Apoptosis Cancer
    Conglobatin (FW-04-806), a macrolide dilactone, is isolated from the culture of Streptomyces conglobatus. Conglobatin is an orally active Hsp90 inhibitor. Conglobatin can bind to the N-terminal domain of Hsp90 and disrupt Hsp90-Cdc37 complex formation. Conglobatin induces apoptosis in human breast cancer cells and esophageal squamous cell carcinoma cells, and exhibits antitumor activity in vivo .
    Conglobatin
  • HY-P3990
    Coibamide A

    		VEGFR Autophagy Apoptosis Cancer
    Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, shows potent antiproliferative activity. Coibamide A induces autophagosome accumulation via an mTOR-independent mechanism. Coibamide A induces apoptosis. Coibamide A inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts .
    Coibamide A
  • HY-17411R
    Limonin (Standard)

    Limonoic acid 3,19:16,17 dilactone (Standard)

    		 Reference Standards HIV Apoptosis Endogenous Metabolite Cytochrome P450 P-glycoprotein Infection Cancer
    Limonin (Standard) is the analytical standard of Limonin. This product is intended for research and analytical applications. Limonin inhibits HIV-1 with an EC50 of 60.0 μM. Limonin induces human colon adenocarcinoma cells apoptosis with an IC50 of 54.74 μM. Limonin has antiviral and antitumor activities .
    Limonin (Standard)
  • HY-N8280
    IKD-8344

    		Fungal Infection
    IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species and has diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties. It is cytotoxic to L5178Y murine leukemia cells (IC50=0.54 ng/ml).1 IKD-8344 inhibits growth of the mycelial form of C. albicans (MIC=6.25 μg/mL) and potentiates the activity of polymyxin B against the multidrug-resistant pathogenic bacterium B. cenocepacia.
    IKD-8344
  • HY-P1720
    Telomycin

    		Antibiotic Bacterial Infection
    Telomycin is a calcium-dependent antibiotic, which can be produced by Streptomyces. Telomycin inhibits gram-positive bacteria, including multidrug-resistant (MDR) pathogens .
    Telomycin
  • HY-N3215
    Nagilactone C

    		Others Others
    Nagilactone C is a diterpene dilactone compound isolated from Podocarpus neriifolius. Nagilactone C has potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines .
    Nagilactone C
  • HY-N19224
    Pulvinic acid dilactone

    		Drug Derivative Bacterial Infection Neurological Disease Cancer
    Pulvinic acid dilactone (Compound 1) is a pulvinic acid derivative and Antibacterial agent. Pulvinic acid dilactone can be isolated from the lichen Candelaria concolor. Pulvinic acid dilactone moderately inhibits the growth of Bacillus subtilis. Pulvinic acid dilactone exerts positive inotropic effects. Pulvinic acid dilactone can be used in studies related to Bacillus subtilis infections and leukemia .
    Pulvinic acid dilactone
  • HY-N14729
    De-N-methylpamamycin-593A

    		Fungal Infection
    De-N-methylpamamycin-593A is a 16-membered ring macrocyclic dilactone. De-N-methylpamamycin-593A has Aerial Mycelium-inducing activity .
    De-N-methylpamamycin-593A
  • HY-N14730
    De-N-methylpamamycin-593B

    		Fungal Infection
    De-N-methylpamamycin-593B is a 16-membered ring macrocyclic dilactone. De-N-methylpamamycin-593B has Aerial Mycelium-inducing activity .
    De-N-methylpamamycin-593B
  • HY-135765
    Micordilin

    		Others Cancer
    Micordilin is a complex Elemanolide-like compound isolated from the medicinal plant Mikania cordifolia. Micordilin is an endogenous hemiacetal of C-14-acetylated dialdehyde elemanolide. Micordilin has antitumor dilactone properties and can be used in the study of antitumor activity .
    Micordilin
  • HY-P1709
    Protactin

    		Bacterial Infection
    Protactin is a pentapeptide lactone produced by Streptomyces cucumeris strain L703-4 (ATCC 53784) with significant antioxidant properties. Protactin can be converted to actinomycin Zp by ferrocyanide oxidation. Actinomycin Zp exhibits potent antibacterial activity in vitro and has significant antitumor effects against P-388 leukemia in a mouse model .
    Protactin
  • HY-P11022
    TL-119

    A-3302-B

    		 Endogenous Metabolite HSV TRP Channel Infection Cancer
    TL-119 (A-3302-B) is a polypeptide. TL-119 can be isolated from the bacteria Micromonospora sp. MAG 9-7 and Saccharomonospora sp. CNQ-490. TL-119 inhibits TRPV-1. TL-119 exhibits antiviral activity against HSV-2. TL-119 possesses anticancer activity against gastric cancer and colorectal cancer .
    TL-119

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