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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
doublecortin
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "doublecortin" in MCE Product Catalog:
6
6 Cited Publications
Synonyms: Purapuridine; Solancarpidine; Solasodin
Category:
Cardiovascular Disease Neurological Disease Plants Infection Alkaloids Piperidine Alkaloids Solanum nigrum Linn. Solanaceae Disease Research Fields Inflammation/Immunology
Target:
6
6 Cited Publications
Target:
Research Areas:
DCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases (IC50: DCLK1=9.5/57.2 nM and DCLK2=31/103 nM in binding and kinase assay, respectively). DCLK1-IN-1 shows low toxicity, and can investigate DCLK1 biology and establish its role in cancer, like DCLK1 + pancreatic ductal adenocarcinoma (PDAC) .
Synonyms: Purapuridine (Standard); Solancarpidine (Standard); Solasodin (Standard)
Cat. No.: HY-178776
Research Areas:
DCLK1-IN-6 (Compound 12n) is a Doublecortin-like kinase 1 (DCLK1) inhibitor with an IC50 of 58 nM. DCLK1-IN-6 significantly inhibits DCLK1 enzyme activity and its mediated inflammatory pathway. DCLK1-IN-6 has remarkable anti-inflammatory activity and significantly alleviates symptoms in acute lung injury (ALI) and sepsis mouse models. DCLK1-IN-6 can be used for acute inflammation diseases research .
Cat. No.: HY-163184
Target:
Research Areas:
DCLK1-IN-3 is a potent and selective doublecortin-like kinase 1 (DCLK1) inhibitor with an IC50 of 47 nM. DCLK1-IN-3 can be used for the research of cancer .
Cat. No.: HY-163185
Target:
Research Areas:
DCLK1-IN-4 (compound D2) is a potent and selective doublecortin-like kinase 1 (DCLK1) inhibitor with an IC50 of 70 nM. DCLK1-IN-4 can be used for the research of cancer .
Cat. No.: HY-P706034
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Serine/threonine-protein kinase DCLK1; doublecortin domain-containing protein 3A; doublecortin-like and CAM kinase-like 1; doublecortin-like kinase 1; DCAMKL1; DCDC3A; KIAA0369
Species:
Source:
Cat. No.: HY-P706031
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Serine/threonine-protein kinase DCLK2; CaMK-like CREB regulatory kinase 2; CL2; CLICK-II; CLICK2; doublecortin domain-containing protein 3B; doublecortin-like and CAM kinase-like 2; doublecortin-like kinase 2; DCAMKL2; DCDC3B; DCK2
Species:
Source:
Cat. No.: HY-P75308
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Serine/threonine-protein kinase DCLK1; doublecortin-like kinase 1; DCAMKL1; DCDC3A
Species:
Source:
Cat. No.: HY-P702660
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Serine/threonine-protein kinase DCLK1; doublecortin-like kinase 1; DCAMKL1; DCDC3A
Species:
Source:
Cat. No.: HY-P75307
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Serine/threonine-protein kinase DCLK1; doublecortin-like kinase 1; DCAMKL1; DCDC3A
Species:
Source:
Cat. No.: HY-P702661
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: DCLK2; doublecortin like kinase 2; CL2; DCK2; CLIK2; DCDC3; CLICK2; DCDC3B; DCAMKL2; CLICK-II
Species:
Source:
Cat. No.: HY-P705803
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DCLK2; doublecortin like kinase 2; CL2; DCK2; CLIK2; DCDC3; CLICK2; DCDC3B; DCAMKL2; CLICK-II
Species:
Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
