DCLK1-IN-6
DCLK1-IN-6 (Compound 12n) is a Doublecortin-like kinase 1 (DCLK1) inhibitor with an IC50 of 58 nM. DCLK1-IN-6 significantly inhibits DCLK1 enzyme activity and its mediated inflammatory pathway. DCLK1-IN-6 has remarkable anti-inflammatory activity and significantly alleviates symptoms in acute lung injury (ALI) and sepsis mouse models. DCLK1-IN-6 can be used for acute inflammation diseases research.
For research use only. We do not sell to patients.
- Formula: C30H35N7O3
- Molecular Weight:541.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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IL-6 |
IKK-β |
Chemical Information
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Molecular Weight 541.64
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Formula C30H35N7O3
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SMILES
CN(C1=NC(NC2=C(C=C(C=C2)C(N3CCC4(CC3)CCNCC4)=O)OC)=NC=C1N(C5=O)C)C6=C5C=CC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)