14 Results for "

fidelity checking

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "fidelity checking" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-K0533

MCE 2× High-Fidelity PCR Master Mix is provided as a simple-to-use, stabilized 2× formulation that includes all components for PCR except sample DNA, primers and water. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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5
5 Cited Publications
Cat. No.: HY-I0960
CAS No.: 66-22-8
Uracil is a pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA base damage that results from the spontaneous or chemically induced deamination of cytosine and is mutagenic at the level of replication. Uracil could potentially alter transcriptional fidelity, resulting in production of mutant proteins .
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1
1 Cited Publications
Cat. No.: HY-K0533A

MCE 2× High-Fidelity PCR Master Mix (with Dye) is a new type of ready-to-use high-fidelity PCR amplification master mix.During the reaction, only template and primers need to be added to quickly and efficiently complete the PCR process, reducing the risk of contamination during operation. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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Cat. No.: HY-147054
CAS No.: 2243882-74-6
Purity:  99.46%
Synonyms: Debio 0123; WEE1-IN-5
Target:  

Wee1 CDK

Research Areas:  

Cancer

Zedoresertib (Debio 0123) is a potent WEE1 inhibitor with an IC50 value of 0.8 nM. Zedoresertib inhibits phospho-CDC2. Zedoresertib abrogates the G2 check point, increasing sensitivity to DNA damaging agents in cancer cells. Zedoresertib can be used for researching anticancer .
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Cat. No.: HY-111648
CAS No.: 7803-88-5
Purity:  99.65%
Research Areas:  

Others

6-O-Methyl Guanosine is a Ribonucleoside. Replacement of the conserved G5, G8 or G12 residues in hammerhead ribozymes with 6-O-Methyl Guanosine reduces kcat without altering Km. 6-O-Methyl Guanosine exerts position-dependent regulatory effects on ribosomal velocity and fidelity. When 6-O-Methyl Guanosine is located at the first or third position of a codon, it decreases the accuracy of tRNA selection. When 6-O-Methyl Guanosine is located at the second position of a codon, it slows down the peptide bond formation rate of cognate aminoacyl-tRNA but does not change the reaction rate of near-cognate aminoacyl-tRNA .
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Cat. No.: HY-E70376
CAS No.: 2304873-45-6
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Pfu DNA Polymerase is an important enzyme in PCR-related experiments, which is initially found in Pyrococcus furiosus. Pfu DNA Polymerase exhibits thermostability and high fidelity .
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Cat. No.: HY-N11857
CAS No.: 25876-11-3
Gentamicin C2 is an aminoglycoside antibiotic with broad-spectrum bactericidal activity, selectively binding to the bacterial 16S rRNA A-site. Gentamicin C2 interferes with protein synthesis initiation and translation fidelity to exert bactericidal effects. Gentamicin C2 can be used for the research of bacterial infections .
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Cat. No.: HY-P2632A
CAS No.: 2100275-49-6
Synonyms: RADA16 hydrochloride
Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

RAD16-I hydrochloride, a soft nanofibrous self-assembling peptide, is a suitable microenvironment for human mesenchymal stem cells’ (hMSC) proliferation and differentiation into chondrocytes . RAD16-I is a well-studied ionic complementary peptide was used as a model to check potential amyloid-like staining properties of SAPNFs .
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Cat. No.: HY-W777859
CAS No.: 1246815-59-7
Synonyms: 5-Methylcytosine hydrochloride-13C,15N2
5-Methyl cytosine- 13C, 15N2 hydrochloride (5-Methylcytosine hydrochloride- 13C, 15N2) is the 13C- and 15N-labeled 5-Methylcytosine hydrochloride (HY-W008091A). 5-Methylcytosine hydrochloride plays a crucial role in regulating gene expression, facilitating genomic imprinting, and suppressing transposable elements, while also being intricately linked to translational fidelity and tRNA recognition.
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Cat. No.: HY-P2937
CAS No.: 9012-90-2
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

DNA polymerase is a polymerase agent targeting DNA templates. DNA polymerase catalyzes the polymerization of deoxyribonucleotides (dNTPs) to extend DNA strands with high fidelity and processivity. DNA polymerase is promising for research of cancers .
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Cat. No.: HY-158038
CAS No.: 3035323-39-5
Target:  

Aurora Kinase Mitosis

Research Areas:  

Cancer

AurkA allosteric-IN-1 (compound 6h) is an Aurora A (AurkA) inhibitor (IC50: 6.50 μM) that inhibits the catalytic activity and non-catalytic functions of Aurora A. Aurora A regulates the assembly of the bipolar mitotic spindle and the fidelity of chromosome segregation during mitosis and has non-catalytic functions. AurkA allosteric-IN-1 blocks the interaction of AurkA with the activator TPX2 by binding to the Y pocket of AurkA .
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Cat. No.: HY-185956
Target:  

mRNA

Research Areas:  

Others

eSpCas9 mRNA (N1-methyl-pseudouridine) is a high-fidelity version of SpCas9 with lower off-target rates while maintaining high targeted genome editing efficiency.
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Cat. No.: HY-P701614
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDHD1; WD Repeat And HMG-Box DNA Binding Protein 1; AND-1; CHTF4; CTF4; WD Repeat And HMG-Box DNA-Binding Protein 1; Acidic Nucleoplasmic DNA-Binding Protein 1; AND1; CTF4, Chromosome Transmission fidelity Factor 4 Homolog (S. Cerevisiae); CTF4, Chromosom
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P701615
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDHD1; WD Repeat And HMG-Box DNA Binding Protein 1; AND-1; CHTF4; CTF4; WD Repeat And HMG-Box DNA-Binding Protein 1; Acidic Nucleoplasmic DNA-Binding Protein 1; AND1; CTF4, Chromosome Transmission fidelity Factor 4 Homolog (S. Cerevisiae); CTF4, Chromosom
Species:  
Human
Source:  
HEK293
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