Search Result

Results for "

flavone inhibitor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (3) Amyloid-β (1) Apoptosis (6) Aurora Kinase (2) Bacterial (4) Bcl-2 Family (4) Caspase (5) CDK (1) Cryptochrome (2) Cytochrome P450 (2) Dengue Virus (1) DNA/RNA Synthesis (2) ERK (2) Flavivirus (1) Fungal (2) Glutathione Peroxidase (1) HBV (4) HIV (3) IFNAR (2) Interleukin Related (1) Keap1-Nrf2 (1) Microtubule/Tubulin (1) MMP (2) NF-κB (5) NO Synthase (2) p38 MAPK (2) PAI-1 (2) PARP (2) PI3K (1) Pim (2) Reactive Oxygen Species (ROS) (3) Reference Standards (6) Ribosomal S6 Kinase (RSK) (2) STAT (4) TNF Receptor (1) Tyrosinase (2)
By Research Areas:	Cancer (18) Cardiovascular Disease (2) Infection (12) Inflammation/Immunology (9) Metabolic Disease (3) Neurological Disease (1)

By Targets:

Akt (3)

Amyloid-β (1)

Apoptosis (6)

Aurora Kinase (2)

Bacterial (4)

Bcl-2 Family (4)

Caspase (5)

CDK (1)

Cryptochrome (2)

Cytochrome P450 (2)

Dengue Virus (1)

DNA/RNA Synthesis (2)

ERK (2)

Flavivirus (1)

Fungal (2)

Glutathione Peroxidase (1)

HBV (4)

HIV (3)

IFNAR (2)

Interleukin Related (1)

Keap1-Nrf2 (1)

Microtubule/Tubulin (1)

MMP (2)

NF-κB (5)

NO Synthase (2)

p38 MAPK (2)

PAI-1 (2)

PARP (2)

PI3K (1)

Pim (2)

Reactive Oxygen Species (ROS) (3)

Reference Standards (6)

Ribosomal S6 Kinase (RSK) (2)

STAT (4)

TNF Receptor (1)

Tyrosinase (2)

By Research Areas:

Cancer (18)

Cardiovascular Disease (2)

Infection (12)

Inflammation/Immunology (9)

Metabolic Disease (3)

Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0751

Scutellarin Maximum Cited Publications 23 Publications Verification	STAT Akt HIV	Infection Cancer
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC₅₀s of 26 μM, 253 μM and 136 μM, respectively.

HY-N1950

Hispidulin 5+ Cited Publications Dinatin	Pim	Cancer
Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC₅₀ of 2.71 μM.

HY-N7128

Flavanone 1 Publications Verification	Cytochrome P450 ERK p38 MAPK NF-κB MMP PAI-1	Cancer
Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase). Flavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy .

HY-N2424

Flavone 2-Phenyl-4-chromone	CDK Apoptosis Caspase	Cancer
Flavone is an anti-tumor compound that targets cell cycle regulatory proteins (such as cyclin B1) and apoptosis-related factors (such as p21_waf1, PIG3). Flavone selectively induces mitochondrial-mediated apoptosis pathways in tumor cells, inhibits cyclin B1 protein expression, upregulates p21_waf1, and activates p63/p73 proteins. Flavone has immunomodulatory functions that enhance natural killer cell (NK cell) activity and lymphocyte proliferation. Flavone is used in cancer research, especially for its inhibitory potential in solid tumor models such as esophageal cancer and liver cancer .

HY-N2300

Kuwanon A 1 Publications Verification	NO Synthase	Metabolic Disease Inflammation/Immunology
Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC₅₀ of 10.5 μM.

HY-125911

Gossypin	NF-κB Aurora Kinase Ribosomal S6 Kinase (RSK) Apoptosis Caspase Bcl-2 Family PARP Cryptochrome	Cardiovascular Disease Inflammation/Immunology Cancer
Gossypin is an orally active flavone isolated from Hibiscus vitifolius. Gossypin has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits AURKA and RSK2. Gossypin inhibits invasion and induces apoptosis. Gossypin can be used for gastric cancer study .

HY-119347

Cirsilineol 3 Publications Verification	IFNAR STAT	Inflammation/Immunology Cancer
Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4 ⁺ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .

HY-N4285

Negletein 5,6-Dihydroxy-7-methoxyflavone	TNF Receptor Interleukin Related Reactive Oxygen Species (ROS) Keap1-Nrf2 Amyloid-β	Infection Neurological Disease Inflammation/Immunology Cancer
Negletein (5,6-Dihydroxy-7-methoxyflavone) is a flavone found in Scutellaria. Negletein shows anti-inflammatory activity via inhibiting TNF-α and IL-1β with IC₅₀ values of 16.4 and 6.4 μM, respectively. Negletein can activate Nrf2 and inhibit ROS production. Negletein can enhance the neuroprotective effect of nerve growth factor. Negletein can inhibit amyloid beta-peptide release and accumulation. Negletein can inhibit pathogens biofilms formation. Negletein can be used for the researches of cancer, infection, inflammation and neurological disease, such as colon cancer and Alzheimer's disease .

HY-N11552

Sorbifolin	Glutathione Peroxidase	Inflammation/Immunology
Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC₅₀ value of 19.2 nM .

HY-N2135

Puerarin 6''-O-Xyloside	Apoptosis Caspase Bcl-2 Family Tyrosinase	Metabolic Disease Cancer
Puerarin 6''-O-Xyloside is one of the major iso-flavones found in P. lobata. Puerarin 6''-O-Xyloside inhibits cancer cells proliferation, induces apoptosis by upregulating cleaved caspase-3, 7, 9, Bax and downregulating Bcl-2 levles and inhibits tumor growth in mice. Puerarin 6''-O-Xyloside has anti-osteoporotic activity in ovariectomized mice. Puerarin 6''-O-Xyloside inhibits mushroom tyrosinase with an IC₅₀ of 513.8 μM. Puerarin 6''-O-Xyloside can be used for the research of human lung carcinoma, osteoporosis, melanosis and melanomar .

HY-N6583

Licoflavonol 2 Publications Verification	Bacterial	Infection
Licoflavonol, a minor flavone from the roots of Glycyrrhiza uralensis, is an inhibitor of the Salmonella type III secretion system (T3SS) .

HY-152081

DENV-IN-7	Flavivirus Dengue Virus HIV DNA/RNA Synthesis	Infection
DENV-IN-7, a flavone analog, is a dengue virus (DENV) inhibitor with an EC₅₀ value of 70 nM. DENV-IN-7 has low toxicity against normal cell and anti-dengue activity .

HY-N12394

Norwogonin-8-O-glucuronide	Reactive Oxygen Species (ROS) NO Synthase	Inflammation/Immunology
Norwogonin-8-O-glucuronide is a glucuronide that can be isolated from Scutellaria indica. Norwogonin-8-O-glucuronide has anti-inflammatory activity. Norwogonin-8-O-glucuronide is a flavone glycoside. Norwogonin-8-O-glucuronide inhibits NO production in macrophage RAW264.7 cells with an IC₅₀ above 30 μM .

HY-148781

HBV-IN-30	HBV	Infection
HBV-IN-30 (ex44), a flavone derivative, is a potent covalently closed circular DNA (cccDNA) inhibitor. cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-30 has the potential for the research of HBV infection .

HY-N8788

Baicalein 7-O-β-D-ethylglucuronide	Others	Inflammation/Immunology Cancer
Baicalein 7-O-β-D-ethylglucuronide is a natural flavone glycoside that can be extracted from Scutellaria baicalensis Georgi. Baicalein 7-O-β-D-ethylglucuronide has antioxidant activity. Baicalein 7-O-β-D-ethylglucuronide inhibits FeSO₄-Cys-induced lipid peroxidation of liver homogenate. Baicalein 7-O-β-D-ethylglucuronide also shows strong cytoprotective effect on H₂O₂-induced oxidative damage of human umbilical vein endothelial cells .

HY-N12959

5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone DDR	PI3K Akt NF-κB	Cancer
5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone (DDR) is an anticancer agent that can be extracted from Indigofera ovata. 5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone can inhibit the PI3K/AKT and NF-кB pathways, inhibit the invasion and migration of cancer cells, and has anticancer activity .

HY-157165

Tubulin/PARP-IN-1	Microtubule/Tubulin PARP	Cancer
Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with activity against endometrial cancer. Tubulin/PARP-IN-1 inhibits PARP and tubulin with IC₅₀s of 74 nM (PARP1), 109 nM (PARP2), and 1.4 μM (Microtubule/Tubulin), respectively. Tubulin/PARP-IN-1 can induce apoptosis and autophagy and cause cell cycle arrest in the G2/M phase .

HY-N1950R

Hispidulin (Standard) Dinatin (Standard)	Reference Standards Pim	Cancer
Hispidulin (Standard) is the analytical standard of Hispidulin. This product is intended for research and analytical applications. Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC₅₀ of 2.71 μM.

HY-N1306

Sideroxylin	Bacterial Reactive Oxygen Species (ROS) Apoptosis	Infection Cancer
Sideroxylin is a C-methylated flavone isolated from Callistemon lanceolatus and exerts antimicrobial activity against *Staphylococcus aureus. Sideroxylin inhibits* ovarian cancer cell proliferation and induces apoptosis, causing DNA fragmentation, depolarization of the mitochondrial membrane, the generation of reactive oxygen species (ROS) .

HY-125911R

Gossypin (Standard)	Reference Standards NF-κB Aurora Kinase Ribosomal S6 Kinase (RSK) Apoptosis Bcl-2 Family Caspase Cryptochrome	Cardiovascular Disease Inflammation/Immunology Cancer
Gossypin (Standard) is the analytical standard of Gossypin. This product is intended for research and analytical applications. Gossypin is an orally active flavone isolated from Hibiscus vitifolius. Gossypin has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits AURKA and RSK2. Gossypin inhibits invasion and induces apoptosis. Gossypin can be used for gastric cancer study.

HY-N0751R

Scutellarin (Standard)	Reference Standards STAT Akt HIV	Infection Cancer
Scutellarin (Standard) is the analytical standard of Scutellarin. This product is intended for research and analytical applications. Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC₅₀s of 26 μM, 253 μM and 136 μM, respectively.

HY-N2882

Apigenin-4'-α-L-rhamnoside	HBV	Infection
Apigenin-4'-α-L-rhamnoside is a potent inhibitor of HBV. Apigenin-4'-α-L-rhamnoside inhibits the secretory level of HBV surface antigen (HBsAg) in HepG2.2.15 cells .

HY-148780

HBV-IN-29	HBV	Infection
HBV-IN-29 (ex8), a flavone derivative, is a potent covalently closed circular DNA (cccDNA) inhibitor. cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-29 has the potential for the research of HBV infection .

HY-N7128R

Flavanone (Standard)	Cytochrome P450 Reference Standards ERK p38 MAPK NF-κB MMP PAI-1	Cancer
Flavanone (Standard) is the analytical standard of Flavanone. This product is intended for research and analytical applications. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase). lavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy .

HY-144046

HBV-IN-15	HBV DNA/RNA Synthesis	Infection
HBV-IN-15 is a potent inhibitor of covalently closed circular DNA (cccDNA). cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-15 is a flavone derivative. HBV-IN-16 has the potential for the research of HBV infection (extracted from patent WO2020052774A1, compound 2) .

HY-N16051

Bromoflavone CJ-19784	Bacterial Fungal	Infection
Bromoflavone (CJ-19784) is a flavone that can be isolated from Aspergillus candidus. Bromoflavone shows anti-Mtb activity with an MIC90 value of 1.2 μM. Bromoflavone is also an antifungal agent. Bromoflavone inhibits the growth of pathogenic fungi, Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus with IC₅₀ values of 0.11, 20 and 0.54 μg/mL, respectively. .

HY-119347R

Cirsilineol (Standard)	Reference Standards IFNAR STAT	Inflammation/Immunology Cancer
Cirsilineol (Standard) is the analytical standard of Cirsilineol. This product is intended for research and analytical applications. Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .

HY-N2135R

Puerarin 6''-O-Xyloside (Standard)	Reference Standards Apoptosis Caspase Bcl-2 Family Tyrosinase	Metabolic Disease Cancer
Puerarin 6''-O-Xyloside (Standard) is the analytical standard of Puerarin 6''-O-Xyloside (HY-N2135). This product is intended for research and analytical applications. Puerarin 6''-O-Xyloside is one of the major iso-flavones found in P. lobata. Puerarin 6''-O-Xyloside inhibits cancer cells proliferation, induces apoptosis by upregulating cleaved caspase-3, 7, 9, Bax and downregulating Bcl-2 levles and inhibits tumor growth in mice. Puerarin 6''-O-Xyloside has anti-osteoporotic activity in ovariectomized mice. Puerarin 6''-O-Xyloside inhibits mushroom tyrosinase with an IC₅₀ of 513.8 μM. Puerarin 6''-O-Xyloside can be used for the research of human lung carcinoma, osteoporosis, melanosis and melanomar .

HY-N17348

5,6,7,8-Tetramethoxyflavone	Bacterial Fungal	Infection
5,6,7,8-Tetramethoxyflavone is a flavonoid with antifungal and antibacterial activities, capable of inhibiting the growth of Staphylococcus aureus and Candida albicans. 5,6,7,8-Tetramethoxyflavone can be utilized in research related to infections ^[1].

Scutellarin Maximum Cited Publications 23 Publications Verification	Infection Flavonoids Classification of Application Fields Flavones Labiatae Phenols Polyphenols Plants Medicago truncatula Gaertn. Disease Research Fields Source Classification	STAT Akt HIV
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC₅₀s of 26 μM, 253 μM and 136 μM, respectively.

Hispidulin 5+ Cited Publications Dinatin	Flavonoids Classification of Application Fields Flavones Labiatae Cassia Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	Pim
Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC₅₀ of 2.71 μM.

Flavanone 1 Publications Verification	Flavonoids Classification of Application Fields Leguminosae Flavonones Sophora flavescens Aiton Plants Disease Research Fields Source Classification Cancer	Cytochrome P450 ERK p38 MAPK NF-κB MMP PAI-1
Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase). Flavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy .

Flavone 2-Phenyl-4-chromone	Flavonoids Classification of Application Fields Flavones Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	CDK Apoptosis Caspase
Flavone is an anti-tumor compound that targets cell cycle regulatory proteins (such as cyclin B1) and apoptosis-related factors (such as p21_waf1, PIG3). Flavone selectively induces mitochondrial-mediated apoptosis pathways in tumor cells, inhibits cyclin B1 protein expression, upregulates p21_waf1, and activates p63/p73 proteins. Flavone has immunomodulatory functions that enhance natural killer cell (NK cell) activity and lymphocyte proliferation. Flavone is used in cancer research, especially for its inhibitory potential in solid tumor models such as esophageal cancer and liver cancer .

Kuwanon A 1 Publications Verification	Classification of Application Fields Flavones Metabolic Disease Plants Moraceae Flavonoids other families Phenols Polyphenols Morus alba L. Inflammation/Immunology Disease Research Fields Source Classification	NO Synthase
Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC₅₀ of 10.5 μM.

Gossypin	Malvaceae Cardiovascular Disease Flavonols Flavonoids Classification of Application Fields Phenols Polyphenols Abelmoschus manihot (Linn.) Medicus Plants Inflammation/Immunology Disease Research Fields Source Classification	NF-κB Aurora Kinase Ribosomal S6 Kinase (RSK) Apoptosis Caspase Bcl-2 Family PARP Cryptochrome
Gossypin is an orally active flavone isolated from Hibiscus vitifolius. Gossypin has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits AURKA and RSK2. Gossypin inhibits invasion and induces apoptosis. Gossypin can be used for gastric cancer study .

Cirsilineol 3 Publications Verification	Laburnum anagyroides Medic. Monophenols Flavonoids Classification of Application Fields Flavones Phenols Plants Compositae Inflammation/Immunology Disease Research Fields Source Classification	IFNAR STAT
Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4 ⁺ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .

Negletein 5,6-Dihydroxy-7-methoxyflavone	Flavonoids Flavones Labiatae Phenols Polyphenols Plants Medicago truncatula Gaertn. Source Classification	TNF Receptor Interleukin Related Reactive Oxygen Species (ROS) Keap1-Nrf2 Amyloid-β
Negletein (5,6-Dihydroxy-7-methoxyflavone) is a flavone found in Scutellaria. Negletein shows anti-inflammatory activity via inhibiting TNF-α and IL-1β with IC₅₀ values of 16.4 and 6.4 μM, respectively. Negletein can activate Nrf2 and inhibit ROS production. Negletein can enhance the neuroprotective effect of nerve growth factor. Negletein can inhibit amyloid beta-peptide release and accumulation. Negletein can inhibit pathogens biofilms formation. Negletein can be used for the researches of cancer, infection, inflammation and neurological disease, such as colon cancer and Alzheimer's disease .

Sorbifolin	Pterogyne nitens Tul. Leguminosae Plants Source Classification	Glutathione Peroxidase
Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC₅₀ value of 19.2 nM .

Puerarin 6''-O-Xyloside	Structural Classification Flavonoids other families Classification of Application Fields Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Isoflavones Source Classification	Apoptosis Caspase Bcl-2 Family Tyrosinase
Puerarin 6''-O-Xyloside is one of the major iso-flavones found in P. lobata. Puerarin 6''-O-Xyloside inhibits cancer cells proliferation, induces apoptosis by upregulating cleaved caspase-3, 7, 9, Bax and downregulating Bcl-2 levles and inhibits tumor growth in mice. Puerarin 6''-O-Xyloside has anti-osteoporotic activity in ovariectomized mice. Puerarin 6''-O-Xyloside inhibits mushroom tyrosinase with an IC₅₀ of 513.8 μM. Puerarin 6''-O-Xyloside can be used for the research of human lung carcinoma, osteoporosis, melanosis and melanomar .

Licoflavonol 2 Publications Verification	Infection Flavonols Flavonoids Classification of Application Fields Leguminosae Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Source Classification	Bacterial
Licoflavonol, a minor flavone from the roots of Glycyrrhiza uralensis, is an inhibitor of the Salmonella type III secretion system (T3SS) .

Norwogonin-8-O-glucuronide	Flavonoids Flavones Labiatae Amberboa moschata (L.) DC. Plants Source Classification	Reactive Oxygen Species (ROS) NO Synthase
Norwogonin-8-O-glucuronide is a glucuronide that can be isolated from Scutellaria indica. Norwogonin-8-O-glucuronide has anti-inflammatory activity. Norwogonin-8-O-glucuronide is a flavone glycoside. Norwogonin-8-O-glucuronide inhibits NO production in macrophage RAW264.7 cells with an IC₅₀ above 30 μM .

Baicalein 7-O-β-D-ethylglucuronide	Flavonoids Flavones Labiatae Plants Medicago truncatula Gaertn. Source Classification	Others
Baicalein 7-O-β-D-ethylglucuronide is a natural flavone glycoside that can be extracted from Scutellaria baicalensis Georgi. Baicalein 7-O-β-D-ethylglucuronide has antioxidant activity. Baicalein 7-O-β-D-ethylglucuronide inhibits FeSO₄-Cys-induced lipid peroxidation of liver homogenate. Baicalein 7-O-β-D-ethylglucuronide also shows strong cytoprotective effect on H₂O₂-induced oxidative damage of human umbilical vein endothelial cells .

5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone DDR	Monophenols Flavonoids Flavones Phenols Plants Indigofera aspalathoides Vahl ex DC. Fabaceae Source Classification	PI3K Akt NF-κB
5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone (DDR) is an anticancer agent that can be extracted from Indigofera ovata. 5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone can inhibit the PI3K/AKT and NF-кB pathways, inhibit the invasion and migration of cancer cells, and has anticancer activity .

Hispidulin (Standard) Dinatin (Standard)	Flavonoids Classification of Application Fields Labiatae Cassia Phenols Plants Disease Research Fields Source Classification Cancer	Reference Standards Pim
Hispidulin (Standard) is the analytical standard of Hispidulin. This product is intended for research and analytical applications. Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC₅₀ of 2.71 μM.

Sideroxylin	Infection Eucalyptus saligna Flavonoids Classification of Application Fields Flavones Phenols Polyphenols Myrtaceae Plants Disease Research Fields Source Classification	Bacterial Reactive Oxygen Species (ROS) Apoptosis
Sideroxylin is a C-methylated flavone isolated from Callistemon lanceolatus and exerts antimicrobial activity against *Staphylococcus aureus. Sideroxylin inhibits* ovarian cancer cell proliferation and induces apoptosis, causing DNA fragmentation, depolarization of the mitochondrial membrane, the generation of reactive oxygen species (ROS) .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

flavone inhibitor

Inhibitors & Agonists

NaturalProducts

Natural
Products