Search Result

Results for "

folate receptors

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Folate Receptor (FR) (21) ADC Antibody (5) Antibiotic (1) Antibody-Drug Conjugates (ADCs) (3) Antifolate (10) Biochemical Assay Reagents (76) CD3 (1) DNA Alkylator/Crosslinker (1) Drug Derivative (1) Drug Intermediate (3) Drug-Linker Conjugates for ADC (1) Fluorescent Dye (11) Liposome (4) Microtubule/Tubulin (2) NO Synthase (1) Peptide-Drug Conjugates (PDCs) (2) PROTACs (2) PSMA (1) Radionuclide-Drug Conjugates (RDCs) (2) Reference Standards (1) Thymidylate Synthase (3) Toll-like Receptor (TLR) (1) TRP Channel (1)
By Research Areas:	Cancer (50) Inflammation/Immunology (1) Metabolic Disease (1)
Click Chemistry:	DBCO (6) Alkynes (3)
Oligonucleotides:	Pegylated Lipids (4) Polymers (6)

131

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: Folate Receptor (FR)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-132258A

Mirvetuximab soravtansine (solution) 3 Publications Verification IMGN853 (solution)	Antibody-Drug Conjugates (ADCs) Antifolate	Cancer
Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage .

HY-P99225

Mirvetuximab 2 Publications Verification M9346A	Antifolate ADC Antibody	Cancer
Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .

HY-13728

Plevitrexed ZD 9331; BGC9331	Thymidylate Synthase	Cancer
Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a K_i of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical . Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-144009

DSPE-PEG-Folate, MW 3350	Liposome	Cancer
DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W440888

DSPE-PEG2000-Folate DSPE-PEG2000(2000) folate	Liposome Folate Receptor (FR)	Cancer
DSPE-PEG2000-Folate (DSPE-PEG2000 Folate) is a folate-containing PEG derivative. DSPE-PEG2000-Folate possesses targeting activity and binds to folate receptors in cancer cells. DSPE-PEG2000-Folate can be post-inserted into preformed liposomal bilayers to prepare folate-targeted liposomal formulations. DSPE-PEG2000-Folate forms micelles/lipid bilayers and can be used in studies of targeted drug delivery systems [2].

HY-13615A

EC-17 disodium salt 1 Publications Verification	Fluorescent Dye Folate Receptor (FR)	Cancer
EC-17 disodium salt is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The EC-17 maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively .

HY-P99153

Farletuzumab MORAb-003	Antibiotic	Cancer
Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer .

HY-P99612

Farletuzumab ecteribulin MORAb-202	Antibody-Drug Conjugates (ADCs)	Cancer
Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity.

HY-13615

Folate-FITC EC-17	Fluorescent Dye Folate Receptor (FR)	Cancer
Folate-FITC (EC-17) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The Folate-FITC maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively .

HY-P99225A

Mirvetuximab (powder) 2 Publications Verification M9346A (powder)	Antifolate ADC Antibody	Cancer
Mirvetuximab (M9346A) (powder) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab (powder) is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .

HY-P11024

NVP-EVS459	Folate Receptor (FR)	Cancer
NVP-EVS459 is a Folate Receptor (FR)-targeting radioconjugate. NVP-EVS459 labeled with 177Lu can be used for tumor diagnosis and research .

HY-W1123936B

DBCO-PEG1000-FA DBCO-PEG1000-folate	Folate Receptor (FR)	Cancer
DBCO-PEG1000-FA (DBCO-PEG1000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W440890

DSPE-PEG-Folate, MW 5000	Liposome	Cancer
DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-P10501A

FRα-targeting peptide C7 TFA	Antifolate	Cancer
FRα-targeting peptide C7 TFA is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 TFA can be used in the research of tumor diagnosis and treatment .

HY-10822

Idetrexed BGC 945; ONX-0801; CB 300945	Thymidylate Synthase	Cancer
Idetrexed (ONX 0801) is a thymidylate synthase (TS) inhibitor with a K_i of 1.2 nM. Idetrexed can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .

HY-155884

mPEG4000-amine mPEG4000-NH2	Biochemical Assay Reagents	Cancer
mPEG4000-amine can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-155880

mPEG350-amine mPEG350-NH2	Biochemical Assay Reagents	Cancer
mPEG350-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-155883

mPEG3400-amine mPEG3400-NH2	Biochemical Assay Reagents	Cancer
mPEG3400-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W1123936C

DBCO-PEG2000-FA DBCO-PEG2000-folate	Folate Receptor (FR)	Others
DBCO-PEG2000-FA (DBCO-PEG2000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W591632

PEG-bis-amine (MW 1000) Poly(ethylene glycol)-bis-amine (MW 1000)	Biochemical Assay Reagents	Cancer
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W115607

PEG4000-bis-amine Poly(ethylene glycol)-bis-amine 4000	Biochemical Assay Reagents	Cancer
PEG4000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-10822A

Idetrexed trisodium BGC 945 trisodium; ONX 0801 trisodium; CB 300945 trisodium	Thymidylate Synthase	Cancer
Idetrexed (ONX 0801) trisodium is a thymidylate synthase (TS) inhibitor with a K_i of 1.2 nM. Idetrexed trisodium can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .

HY-16181

EC-0225	Folate Receptor (FR) Microtubule/Tubulin DNA Alkylator/Crosslinker	Cancer
EC-0225, a folate conjugate of two agents- one a potent microtubule inhibiting agent, and the second a DNA alkylating agent. EC-0225 inhibits the growth of folate receptor (FR)-positive KB cells with an IC₅₀ of ~1 nM. EC-0225 can be selectively delivered to advanced FR-positive tumors without causing overt toxicity, such as lung carcinoma .

HY-P10501

FRα-targeting peptide C7	Antifolate	Cancer
FRα-targeting peptide C7 is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 can be used in the research of tumor diagnosis and treatment .

HY-W1123936D

DBCO-PEG3400-FA DBCO-PEG3400-folate	Folate Receptor (FR)	Others
DBCO-PEG-FA (DBCO-PEG-Folate) (MW 3400) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123932A

mPEG2000-FA mPEG2000-folate	Biochemical Assay Reagents	Others
mPEG2000-FA (mPEG2000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-D2523

Cy3-PEG2000-FA	Folate Receptor (FR) Fluorescent Dye
Cy3-PEG2000-FA is a fluorescent folate-PEG derivative with excitation/emission wavelengths of ~550 nm/~570 nm. Cy3-PEG2000-FA can be readily traced by its intense red fluorescent signal. Cy3-PEG2000-FA can be used for cell imaging, folate receptor targeting and detection.

HY-147699

FRα-IN-1	Antifolate	Cancer
FRα-IN-1 (Compound 4) is a tumor-targeting agent. FRα-IN-1 shows selective anticancer activity towards folate receptors (FRα and FRβ) expression cells .

HY-W1123936H

DBCO-PEG10000-FA DBCO-PEG10000-folate	Folate Receptor (FR)	Others
DBCO-PEG10000-FA (DBCO-PEG10000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936E

DBCO-PEG5000-FA DBCO-PEG5000-folate	Folate Receptor (FR)	Others
DBCO-PEG5000-FA (DBCO-PEG5000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-172935

FR-β ligand 1	Antifolate	Cancer
FR-β ligand 1 (III), a **folate receptor**-targeting ligand, possesses antitumor activity, high selectivity, and stronger affinity for folate receptor .

HY-W1123932

mPEG1000-FA mPEG1000-folate	Biochemical Assay Reagents	Others
mPEG1000-FA (mPEG1000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-W440888B

DSPE-PEG3400-Folate	Biochemical Assay Reagents	Others
DSPE-PEG3400-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W440888A

DSPE-PEG1000-Folate	Biochemical Assay Reagents	Others
DSPE-PEG1000-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W440888C

DSPE-PEG5000-Folate	Biochemical Assay Reagents	Others
DSPE-PEG5000-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-115873

Folate-MS432	PROTACs	Cancer
Folate-MS432, a PROTAC, is capable of degrading MEKs in a folate receptor-dependent manner in cancer cells.

HY-174966B

BOC-NH-PEG1000-FA BOC-NH-PEG1000-folate	Biochemical Assay Reagents	Others
BOC-NH-PEG1000-FA (BOC-NH-PEG1000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966

BOC-NH-PEG400-FA BOC-NH-PEG400-folate	Biochemical Assay Reagents	Others
BOC-NH-PEG400-FA (BOC-NH-PEG400-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-W1123945

8-Arm-PEG400-FA 8-Arm-PEG400-folate	Biochemical Assay Reagents	Others
8-Arm-PEG400-FA (8-Arm-PEG400-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-128937

EC1454	Liposome Folate Receptor (FR)	Cancer
EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy .

HY-128939

EC0488	Antifolate	Cancer
EC0488 is used to synthesize EC0531 with folate receptor (FR)-specific and anti-tumor activities .

HY-129880

Desacetylvinblastine hydrazide Deacetylvinblastine hydrazide; DAVLBH	Microtubule/Tubulin	Cancer
Desacetylvinblastine hydrazide (Deacetylvinblastine hydrazide; DAVLBH) is an active component of EC145, a folate-targeted drug conjugate. Desacetylvinblastine hydrazide interferes with the formation of the mitotic spindle, and thus inhibits cell division and leads to cell death. Desacetylvinblastine hydrazide exhibits antitumor activity against folate receptor (FR)-positive tumor .

HY-W888710D

FA-PEG2000-COOH folate-PEG2000-COOH	Biochemical Assay Reagents	Others
FA-PEG2000-COOH (Folate-PEG2000-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .

HY-W888710E

FA-PEG3400-COOH folate-PEG3400-COOH	Biochemical Assay Reagents	Others
FA-PEG3400-COOH (Folate-PEG3400-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .

HY-172936

L-Serine-S2-PEG-Formic acid	Drug Intermediate	Cancer
L-Serine-S2-PEG-Formic acid is a linker for FGT-4 (HY-172934). FGT-4, a TLR7 agonist, is a folate receptor β (FR-β) targeting chimeric molecule .

HY-180461

EET analog 7	Drug Derivative	Cancer
EET analog 7 is an epoxyeicosatrienoic acid (EET) analog that can be conjugated with folate receptor ligands to target kidney cells expressing high levels of folate receptors. EET analog 7 can be used for constructing kidney-targeted drug conjugates .

HY-167412

PLLA5000-PEG2000-FOL	Biochemical Assay Reagents	Others
PLLA5000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG2000-FOL can be used in drug delivery research .

HY-167415

PLLA10000-PEG5000-FOL	Biochemical Assay Reagents	Others
PLLA10000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG5000-FOL can be used in drug delivery research .

HY-167413

PLLA20000-PEG5000-FOL	Biochemical Assay Reagents	Others
PLLA20000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG5000-FOL can be used in drug delivery research .

HY-167411

PLLA5000-PEG5000-FOL	Biochemical Assay Reagents	Others
PLLA5000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG5000-FOL can be used in drug delivery research .

Cat. No.	Product Name	Type

HY-D1716

S0456	Fluorescent Dyes
S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents .

HY-D2523

Cy3-PEG2000-FA	Fluorescent Dyes
Cy3-PEG2000-FA is a fluorescent folate-PEG derivative with excitation/emission wavelengths of ~550 nm/~570 nm. Cy3-PEG2000-FA can be readily traced by its intense red fluorescent signal. Cy3-PEG2000-FA can be used for cell imaging, folate receptor targeting and detection.

HY-D2888A

RB-PEG600-FA Rhodamine B-PEG600-FA	Fluorescent Dyes
RB-PEG600-FA (Rhodamine B-PEG600-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG600-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888

RB-PEG400-FA Rhodamine B-PEG400-FA	Fluorescent Dyes
RB-PEG400-FA (Rhodamine B-PEG400-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG400-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888D

RB-PEG3400-FA Rhodamine B-PEG3400-FA	Fluorescent Dyes
RB-PEG3400-FA (Rhodamine B-PEG3400-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG3400-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888C

RB-PEG2000-FA Rhodamine B-PEG2000-FA	Fluorescent Dyes
RB-PEG2000-FA (Rhodamine B-PEG2000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG2000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888H

RB-PEG10000-FA Rhodamine B-PEG10000-FA	Fluorescent Dyes
RB-PEG10000-FA (Rhodamine B-PEG10000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG10000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888E

RB-PEG5000-FA Rhodamine B-PEG5000-FA	Fluorescent Dyes
RB-PEG5000-FA (Rhodamine B-PEG5000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG5000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

HY-D2888B

RB-PEG1000-FA Rhodamine B-PEG1000-FA	Fluorescent Dyes
RB-PEG1000-FA (Rhodamine B-PEG1000-FA) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Folic acid (FA) (HY-16637). RB-PEG1000-FA can be used for cell imaging, folate receptor targeting and detection (Ex/Em=546/610 nm) .

Cat. No.	Product Name	Type

HY-144009

DSPE-PEG-Folate, MW 3350	Biochemical Assay Reagents
DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W053583

Tetraxetan

1 Publications Verification

DOTA

Biochemical Assay Reagents

Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., ⁶⁸Ga, ¹¹¹In, ¹⁷⁷Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) .

HY-W440888

DSPE-PEG2000-Folate

DSPE-PEG2000(2000) folate

Biochemical Assay Reagents

DSPE-PEG2000-Folate (DSPE-PEG2000 Folate) is a folate-containing PEG derivative. DSPE-PEG2000-Folate possesses targeting activity and binds to folate receptors in cancer cells. DSPE-PEG2000-Folate can be post-inserted into preformed liposomal bilayers to prepare folate-targeted liposomal formulations. DSPE-PEG2000-Folate forms micelles/lipid bilayers and can be used in studies of targeted drug delivery systems [2].

HY-155882

mPEG750-amine

mPEG750-NH2

Biochemical Assay Reagents

mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells .

HY-W1123936B

DBCO-PEG1000-FA

DBCO-PEG1000-folate

Biochemical Assay Reagents

DBCO-PEG1000-FA (DBCO-PEG1000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W440890

DSPE-PEG-Folate, MW 5000	Biochemical Assay Reagents
DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-155884

mPEG4000-amine mPEG4000-NH2	Biochemical Assay Reagents
mPEG4000-amine can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-155880

mPEG350-amine mPEG350-NH2	Biochemical Assay Reagents
mPEG350-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-155883

mPEG3400-amine mPEG3400-NH2	Biochemical Assay Reagents
mPEG3400-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W053583R

Tetraxetan (Standard)

DOTA (Standard)

Biochemical Assay Reagents

Tetraxetan (Standard) is the analytical standard of Tetraxetan (HY-W053583). This product is intended for research and analytical applications. Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., ⁶⁸Ga, ¹¹¹In, ¹⁷⁷Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) .

HY-W1123936C

DBCO-PEG2000-FA

DBCO-PEG2000-folate

Biochemical Assay Reagents

DBCO-PEG2000-FA (DBCO-PEG2000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W591632

PEG-bis-amine (MW 1000) Poly(ethylene glycol)-bis-amine (MW 1000)	Biochemical Assay Reagents
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W115607

PEG4000-bis-amine Poly(ethylene glycol)-bis-amine 4000	Biochemical Assay Reagents
PEG4000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W1123936D

DBCO-PEG3400-FA

DBCO-PEG3400-folate

Biochemical Assay Reagents

DBCO-PEG-FA (DBCO-PEG-Folate) (MW 3400) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123932A

mPEG2000-FA mPEG2000-folate	Biochemical Assay Reagents
mPEG2000-FA (mPEG2000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-W1123936H

DBCO-PEG10000-FA

DBCO-PEG10000-folate

Biochemical Assay Reagents

DBCO-PEG10000-FA (DBCO-PEG10000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936E

DBCO-PEG5000-FA

DBCO-PEG5000-folate

Biochemical Assay Reagents

DBCO-PEG5000-FA (DBCO-PEG5000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123932

mPEG1000-FA mPEG1000-folate	Biochemical Assay Reagents
mPEG1000-FA (mPEG1000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-W440888B

DSPE-PEG3400-Folate	Biochemical Assay Reagents
DSPE-PEG3400-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W440888A

DSPE-PEG1000-Folate	Biochemical Assay Reagents
DSPE-PEG1000-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W440888C

DSPE-PEG5000-Folate	Biochemical Assay Reagents
DSPE-PEG5000-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-174966B

BOC-NH-PEG1000-FA BOC-NH-PEG1000-folate	Biochemical Assay Reagents
BOC-NH-PEG1000-FA (BOC-NH-PEG1000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966

BOC-NH-PEG400-FA BOC-NH-PEG400-folate	Biochemical Assay Reagents
BOC-NH-PEG400-FA (BOC-NH-PEG400-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-W1123945

8-Arm-PEG400-FA 8-Arm-PEG400-folate	Biochemical Assay Reagents
8-Arm-PEG400-FA (8-Arm-PEG400-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W888710D

FA-PEG2000-COOH folate-PEG2000-COOH	Biochemical Assay Reagents
FA-PEG2000-COOH (Folate-PEG2000-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .

HY-W888710E

FA-PEG3400-COOH folate-PEG3400-COOH	Biochemical Assay Reagents
FA-PEG3400-COOH (Folate-PEG3400-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .

HY-167412

PLLA5000-PEG2000-FOL	Biochemical Assay Reagents
PLLA5000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG2000-FOL can be used in drug delivery research .

HY-167415

PLLA10000-PEG5000-FOL	Biochemical Assay Reagents
PLLA10000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG5000-FOL can be used in drug delivery research .

HY-167413

PLLA20000-PEG5000-FOL	Biochemical Assay Reagents
PLLA20000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG5000-FOL can be used in drug delivery research .

HY-167411

PLLA5000-PEG5000-FOL	Biochemical Assay Reagents
PLLA5000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG5000-FOL can be used in drug delivery research .

HY-167416

PLLA10000-PEG2000-FOL	Biochemical Assay Reagents
PLLA10000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG2000-FOL can be used in drug delivery research .

HY-167414

PLLA20000-PEG2000-FOL	Biochemical Assay Reagents
PLLA20000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG2000-FOL can be used in drug delivery research .

HY-W1123932B

mPEG5000-FA mPEG5000-folate	Biochemical Assay Reagents
mPEG5000-FA (mPEG5000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966D

BOC-NH-PEG3400-FA BOC-NH-PEG3400-folate	Biochemical Assay Reagents
BOC-NH-PEG3400-FA (BOC-NH-PEG3400-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966E

BOC-NH-PEG5000-FA BOC-NH-PEG5000-folate	Biochemical Assay Reagents
BOC-NH-PEG5000-FA (BOC-NH-PEG5000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966C

BOC-NH-PEG2000-FA BOC-NH-PEG2000-folate	Biochemical Assay Reagents
BOC-NH-PEG2000-FA (BOC-NH-PEG2000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966H

BOC-NH-PEG10000-FA BOC-NH-PEG10000-folate	Biochemical Assay Reagents
BOC-NH-PEG10000-FA (BOC-NH-PEG10000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174966A

BOC-NH-PEG600-FA BOC-NH-PEG600-folate	Biochemical Assay Reagents
BOC-NH-PEG600-FA (BOC-NH-PEG600-Folate) is a PEG derivative modified with Folic acid (HY-16637). Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-W1123921E

4-Arm-PEG5000-FA 4-Arm-PEG5000-folate	Biochemical Assay Reagents
4-Arm-PEG5000-FA (4-Arm-PEG5000-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W1123921H

4-Arm-PEG10000-FA 4-Arm-PEG10000-folate	Biochemical Assay Reagents
4-Arm-PEG10000-FA (4-Arm-PEG10000-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W1123921

4-Arm-PEG400-FA 4-Arm-PEG400-folate	Biochemical Assay Reagents
4-Arm-PEG400-FA (4-Arm-PEG400-folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W1123921A

4-Arm-PEG600-FA 4-Arm-PEG600-folate	Biochemical Assay Reagents
4-Arm-PEG600-FA (4-Arm-PEG600-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W1123945E

8-Arm-PEG5000-FA 8-Arm-PEG5000-folate	Biochemical Assay Reagents
8-Arm-PEG5000-FA (8-Arm-PEG5000-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W1123921C

4-Arm-PEG2000-FA 4-Arm-PEG2000-folate	Biochemical Assay Reagents
4-Arm-PEG2000-FA (4-Arm-PEG2000-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W1123945H

8-Arm-PEG10000-FA 8-Arm-PEG10000-folate	Biochemical Assay Reagents
8-Arm-PEG10000-FA (8-Arm-PEG10000-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W1123921B

4-Arm-PEG1000-FA 4-Arm-PEG1000-folate	Biochemical Assay Reagents
4-Arm-PEG1000-FA (4-Arm-PEG1000-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-W1123921D

4-Arm-PEG3400-FA 4-Arm-PEG3400-folate	Biochemical Assay Reagents
4-Arm-PEG3400-FA (4-Arm-PEG3400-Folate) is a PEG derivative with one Folic acid (HY-16637) molecule attached to each end of the PEG chain. Folic acid has a high affinity for folate receptors and can be used for targeted drug delivery to cell membrane receptors .

HY-174960E

6-Arm-PEG5000-FA

6-Arm-PEG5000-folate

Biochemical Assay Reagents

6-Arm-PEG5000-FA (6-Arm-PEG5000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174960B

6-Arm-PEG1000-FA

6-Arm-PEG1000-folate

Biochemical Assay Reagents

6-Arm-PEG1000-FA (6-Arm-PEG1000-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

HY-174960D

6-Arm-PEG3400-FA

6-Arm-PEG3400-folate

Biochemical Assay Reagents

6-Arm-PEG3400-FA (6-Arm-PEG3400-Folate) is a PEG derivative modified with Folic acid (HY-16637). Polyethylene glycol can increase solubility and stability and reduce the immunogenicity of peptides and proteins. It can also inhibit the nonspecific binding of charged molecules to modified surfaces. Folic acid (-FA) has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .

Cat. No.	Product Name	Target	Research Area

HY-P10762

Ricorfotide vedotin CBP-1008; LDC 10B	Peptide-Drug Conjugates (PDCs) Folate Receptor (FR) TRP Channel	Cancer
Ricorfotide vedotin (CBP-1008) is a dual-ligand peptide-drug conjugate (PDC) conjugated to MMAE (HY-15162), targeting Folate receptor α (FRα) and TRPV6. Ricorfotide vedotin binds to FRα with high affinity and TRPV6 with low affinity. Ricorfotide vedotin has antitumor activity, and can be used in advanced solid tumor research (eg: colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma and follicular dendritic cell sarcoma) .

HY-P11024

NVP-EVS459	Folate Receptor (FR)	Cancer
NVP-EVS459 is a Folate Receptor (FR)-targeting radioconjugate. NVP-EVS459 labeled with 177Lu can be used for tumor diagnosis and research .

HY-P10501A

FRα-targeting peptide C7 TFA	Antifolate	Cancer
FRα-targeting peptide C7 TFA is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 TFA can be used in the research of tumor diagnosis and treatment .

HY-P10740

CBP-1018	Peptide-Drug Conjugates (PDCs) PSMA Folate Receptor (FR)	Cancer
CBP-1018 is a PDC (peptide-drug conjugate) formed by conjugating Monomethyl auristatin E (HY-15162) to a dual-targeting ligand of FLOR1/PSMA (prostate-specific membrane antigen) via a linker (HY-78738). CBP-1018 binds to FLOR1 and prostate-specific membrane antigen (PSMA). CBP-1018 is applicable to the research of solid tumors and metastatic castration-resistant prostate cancer .

HY-P10501

FRα-targeting peptide C7	Antifolate	Cancer
FRα-targeting peptide C7 is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 can be used in the research of tumor diagnosis and treatment .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99225

Mirvetuximab 2 Publications Verification M9346A	Antifolate ADC Antibody	Cancer
Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .

HY-P99153

Farletuzumab MORAb-003	Antibiotic	Cancer
Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer .

HY-P99225A

Mirvetuximab (powder) 2 Publications Verification M9346A (powder)	Antifolate ADC Antibody	Cancer
Mirvetuximab (M9346A) (powder) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab (powder) is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research .

HY-P992124

Onvontatug BAT8006 Antibody; BAT-6028	Folate Receptor (FR)	Cancer
Onvontatug (BAT8006 Antibody) is a humanized monoclonal antibody targeting folate receptor α (FRα). Onvontatug can be used to construct antibody-drug conjugates (ADCs), such as BAT8006. It is applicable to research related to platinum-resistant ovarian cancer .

HY-P992002

AMT-151 Antibody	ADC Antibody	Cancer
AMT-151 Antibody is a monoclonal antibody inhibitor targeting folate receptor α. AMT-151 Antibody can be used to synthesize the antibody-drug conjugate (ADC) AMT-151. AMT-151 Antibody can be used to research related to cancer .

HY-P992003

IKS012 Antibody IKS01 Antibody	ADC Antibody	Cancer
IKS012 (IKS01) Antibody is a monoclonal antibody inhibitor targeting folate receptor α (FRA). IKS012 Antibody can be used to synthesize the antibody-drug conjugate (ADC) IKS012. IKS012 Antibody can be used to research related to platinum-resistant ovarian cancer .

HY-P992112

Eliroptamig	Folate Receptor (FR) CD3	Cancer
Eliroptamig is a multispecific antibody targeting albumin, folate receptor α (FOLR1) and cluster of differentiation 3 (CD3). Eliroptamig extends its half-life by binding to albumin, while targeting FOLR1 on tumor cells and activating T cells to achieve precise tumor killing .

HY-P992004

KHK2805 RA15-7, HuRA15-7Acc	Folate Receptor (FR)	Cancer
KHK2805 (RA15-7) is a humanized antibody against folate receptor α (FOLR1), with a K_d of 0.647 nM for human FOLR1. KHK2805 binds to a unique epitope of FOLR1 and mediates antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity against FOLR1-expressing cells. KHK2805 exhibits cytotoxicity against both ovarian cancer cells and Platinum (HY-W096169D)-resistant ovarian cancer cells. KHK2805 can be used for the research of tumors such as ovarian cancer .

HY-P992510

Sofetabart LY-4170156 Antibody; MBK-103 Antibody	ADC Antibody Folate Receptor (FR)	Cancer
Sofetabart (LY-4170156 Antibody) is an Fc-silenced, humanized IgG1 antibody targeting FRα, a composition of antibody drug conjugate (ADC) LY-4170156. Sofetabart can be used for the research of Platinum-resistant ovarian cancer and platinum-sensitive ovarian cancer .

Cat. No.	Product Name		Classification

HY-13728

Plevitrexed ZD 9331; BGC9331		Alkynes
Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a K_i of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical . Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-148194

SC239		DBCO
SC239 is a cleavable 2-aminophenyl hemiasterlin agent-linker. SC239 can be as the agent-linker for ADC . SC239 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W1123936B

DBCO-PEG1000-FA DBCO-PEG1000-folate		DBCO
DBCO-PEG1000-FA (DBCO-PEG1000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-10822

Idetrexed BGC 945; ONX-0801; CB 300945		Alkynes
Idetrexed (ONX 0801) is a thymidylate synthase (TS) inhibitor with a K_i of 1.2 nM. Idetrexed can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .

HY-W1123936C

DBCO-PEG2000-FA DBCO-PEG2000-folate		DBCO
DBCO-PEG2000-FA (DBCO-PEG2000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-10822A

Idetrexed trisodium BGC 945 trisodium; ONX 0801 trisodium; CB 300945 trisodium		Alkynes
Idetrexed (ONX 0801) trisodium is a thymidylate synthase (TS) inhibitor with a K_i of 1.2 nM. Idetrexed trisodium can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .

HY-W1123936D

DBCO-PEG3400-FA DBCO-PEG3400-folate		DBCO
DBCO-PEG-FA (DBCO-PEG-Folate) (MW 3400) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936H

DBCO-PEG10000-FA DBCO-PEG10000-folate		DBCO
DBCO-PEG10000-FA (DBCO-PEG10000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

HY-W1123936E

DBCO-PEG5000-FA DBCO-PEG5000-folate		DBCO
DBCO-PEG5000-FA (DBCO-PEG5000-Folate) is a multifunctional bioconjugation reagent, which is a copolymer of DBCO and Folic acid (FA) (HY-16637) and can target folate receptors (FR). Folate receptors are highly overexpressed on the surface of many cancer cells (such as lung cancer, nasopharyngeal cancer, ovarian cancer, etc.), but exhibit extremely low expression levels in normal tissues. DBCO-PEG-FA can be used for click chemistry conjugation via its DBCO terminal, and thus applies to various bioconjugation and drug delivery applications .

Cat. No.	Product Name		Classification

HY-144009

DSPE-PEG-Folate, MW 3350		Pegylated Lipids
DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-W440888

DSPE-PEG2000-Folate DSPE-PEG2000(2000) folate		Pegylated Lipids
DSPE-PEG2000-Folate (DSPE-PEG2000 Folate) is a folate-containing PEG derivative. DSPE-PEG2000-Folate possesses targeting activity and binds to folate receptors in cancer cells. DSPE-PEG2000-Folate can be post-inserted into preformed liposomal bilayers to prepare folate-targeted liposomal formulations. DSPE-PEG2000-Folate forms micelles/lipid bilayers and can be used in studies of targeted drug delivery systems [2].

HY-155882

mPEG750-amine mPEG750-NH2		Polymers
mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells .

HY-W440890

DSPE-PEG-Folate, MW 5000		Pegylated Lipids
DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .

HY-155884

mPEG4000-amine mPEG4000-NH2		Polymers
mPEG4000-amine can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-155880

mPEG350-amine mPEG350-NH2		Polymers
mPEG350-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-155883

mPEG3400-amine mPEG3400-NH2		Polymers
mPEG3400-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W591632

PEG-bis-amine (MW 1000) Poly(ethylene glycol)-bis-amine (MW 1000)		Polymers
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W115607

PEG4000-bis-amine Poly(ethylene glycol)-bis-amine 4000		Polymers
PEG4000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-W440888C

DSPE-PEG5000-Folate		Pegylated Lipids
DSPE-PEG5000-Folate is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .

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