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functional unit

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By Targets:	ADC Linker (2) Biochemical Assay Reagents (9) Fluorescent Dye (1) Poly(ADP-ribose) Glycohydrolase (PARG) (2) Reference Standards (1)
By Research Areas:	Cancer (2)
Click Chemistry:	DBCO (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-159529

DBCO-PEG4-Eosin 5-isothiocyanate DBCO-PEG4-Eosin Y	Fluorescent Dye	Others
DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.

HY-135782

iso-ADP ribose	Poly(ADP-ribose) Glycohydrolase (PARG)	Cancer
iso-ADP ribose is the small-molecule ligand for protein nucleic acid modification, comprising parts of two consecutive ADP-ribosyl units within the PAR chain. iso-ADP ribose specifically binds WWE, FHA and OB-fold domains, enabling PAR-dependent functional responses like ubiquitylation and supporting DNA damage signaling and repair. iso-ADP ribose can be used for cancer research .

HY-N16321

C18:0 DG-PEG2K-triGalNAc	Biochemical Assay Reagents	Others
C18:0 DG-PEG2K-triGalNAc is a functionalized PEG lipid that consists of a C18:0 DG unit conjugated to a triGalNAc. C18:0 DG-PEG2K-triGalNAc can be used to prepare lipid nanoparticles for drug delivery.

HY-135782A

iso-ADP ribose TEA	Poly(ADP-ribose) Glycohydrolase (PARG)	Cancer
iso-ADP ribose TEA is the small-molecule ligand for protein nucleic acid modification, comprising parts of two consecutive ADP-ribosyl units within the PAR chain. iso-ADP ribose TEA specifically binds WWE, FHA and OB-fold domains, enabling PAR-dependent functional responses like ubiquitylation and supporting DNA damage signaling and repair. iso-ADP ribose TEA can be used for cancer research .

HY-151766

DACN(Tos,Suc-OH)	ADC Linker	Others
DACN(Tos,Suc-OH) is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. DACNs possess high thermal and chemical stability along with comparable click reactivity .

HY-151754

DACN(Tos2,6-OH)	ADC Linker	Others
DACN(Tos2,6-OH) is a click chemistry reagent containing an Azide. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. The reactivity of an alkyne heavily depends on the electronic and steric characteristics of the substituents as well as structural strain. In comparison to nonbent acyclic alkynes, cyclononyne alkynes show remarkably high reactivity. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. In comparison to cyclooctynes, DACNs possess high thermal and chemical stability along with comparable click reactivity . DACN(Tos2,6-OH) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-121939

6-Hydroxy-L-DOPA	Biochemical Assay Reagents	Others
6-Hydroxy-L-DOPA is a nucleic acid functionalized with electron-donating units .

HY-121939R

6-Hydroxy-L-DOPA (Standard)	Reference Standards Biochemical Assay Reagents	Others
6-Hydroxy-L-DOPA (Standard) is the analytical standard of 6-Hydroxy-L-DOPA. This product is intended for research and analytical applications. 6-Hydroxy-L-DOPA is a nucleic acid functionalized with electron-donating units .

HY-N16323

DSPE-PEG2K-triGalNAc (II) ammonium	Biochemical Assay Reagents	Others
DSPE-PEG2K-triGalNAc (II) ammonium is a functionalized PEG lipid that consists of a DSPE unit conjugated to a triGalNAc. DSPE-PEG2K-triGalNAc (II) ammonium can be used to prepare lipid nanoparticles for drug delivery.

HY-W190743

Br-PEG8-OH	Biochemical Assay Reagents	Others
Br-PEG8-OH is a PEG derivative that consists of a bromine atom (Br), eight PEG units, and a hydroxyl group (-OH). The bromine group is a common functional group in chemical reactions and can be used for alkylation reactions, coupling reactions, or the introduction of other functional groups. Br-PEG8-OH can be used as a polymer-based material or as a modifier for biomolecules .

HY-174948

NHS-PEG1000-CHO NHS-PEG1000-Aldehyde	Biochemical Assay Reagents	Others
NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-174948C

NHS-PEG5000-CHO NHS-PEG5000-Aldehyde	Biochemical Assay Reagents	Others
NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-174948B

NHS-PEG3400-CHO NHS-PEG3400-Aldehyde	Biochemical Assay Reagents	Others
NHS-PEG3400-CHO (NHS-PEG3400-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-174948A

NHS-PEG2000-CHO NHS-PEG2000-Aldehyde	Biochemical Assay Reagents	Others
NHS-PEG2000-CHO (NHS-PEG2000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

DBCO-PEG4-Eosin 5-isothiocyanate DBCO-PEG4-Eosin Y	Fluorescent Dye
DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.

Cat. No.	Product Name	Type

HY-W190743

Br-PEG8-OH	Biochemical Assay Reagents
Br-PEG8-OH is a PEG derivative that consists of a bromine atom (Br), eight PEG units, and a hydroxyl group (-OH). The bromine group is a common functional group in chemical reactions and can be used for alkylation reactions, coupling reactions, or the introduction of other functional groups. Br-PEG8-OH can be used as a polymer-based material or as a modifier for biomolecules .

HY-174948

NHS-PEG1000-CHO NHS-PEG1000-Aldehyde	Biochemical Assay Reagents
NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-174948C

NHS-PEG5000-CHO NHS-PEG5000-Aldehyde	Biochemical Assay Reagents
NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-174948B

NHS-PEG3400-CHO NHS-PEG3400-Aldehyde	Biochemical Assay Reagents
NHS-PEG3400-CHO (NHS-PEG3400-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-174948A

NHS-PEG2000-CHO NHS-PEG2000-Aldehyde	Biochemical Assay Reagents
NHS-PEG2000-CHO (NHS-PEG2000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16321

C18:0 DG-PEG2K-triGalNAc	Lipid	Biochemical Assay Reagents
C18:0 DG-PEG2K-triGalNAc is a functionalized PEG lipid that consists of a C18:0 DG unit conjugated to a triGalNAc. C18:0 DG-PEG2K-triGalNAc can be used to prepare lipid nanoparticles for drug delivery.

HY-N16323

DSPE-PEG2K-triGalNAc (II) ammonium	Lipid	Biochemical Assay Reagents
DSPE-PEG2K-triGalNAc (II) ammonium is a functionalized PEG lipid that consists of a DSPE unit conjugated to a triGalNAc. DSPE-PEG2K-triGalNAc (II) ammonium can be used to prepare lipid nanoparticles for drug delivery.

Cat. No.	Product Name		Classification

HY-159529

DBCO-PEG4-Eosin 5-isothiocyanate DBCO-PEG4-Eosin Y		DBCO
DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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