human ROR1

By Targets:	ROR (4) Akt (1) Antibiotic (1) Apoptosis (1) Bacterial (1) Caspase (1) ERK (1) GSK-3 (1) JNK (1) Ligands for Target Protein for PROTAC (1) NF-κB (1) PI3K (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (4) Infection (1) Inflammation/Immunology (1) Metabolic Disease (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Targets Recommended: ROR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-135319

Strictinin	Bacterial Antibiotic ERK JNK NF-κB ROR Apoptosis Caspase GSK-3 Akt PI3K	Infection Metabolic Disease Inflammation/Immunology Cancer
Strictinin is an orally active phenolic compound. Strictinin reduces xanthine oxidase activity, uric acid production, and the activation of ERK1/2, JNK, NF-κB, and NLRP3 inflammasome components in hepatocytes treated with Xanthine (HY-W017389). Strictinin decreases elevated serum uric acid levels and enhanced xanthine oxidase activity in mice treated with potassium oxonate. Strictinin acts as a *ROR1* inhibitor and exhibits anticancer activity against highly aggressive non-androgen-dependent prostate cancer. Strictinin induces cancer cell apoptosis (apoptosis), arrests cell cycle, and inhibits cancer cell migration, invasion, and epithelial-mesenchymal transition. Strictinin modulates gut microbiota, inhibits bacterial growth and biofilm formation, accelerates small intestinal transit, and blocks viral entry and replication. Strictinin can be used in research related to hyperuricemia, androgen receptor-negative non-androgen-dependent prostate cancer, triple-negative breast cancer, bacterial infections, constipation, coronavirus infections, dental caries, and infections caused by influenza A, influenza B, and human parainfluenza virus type 1 .

HY-RS12124

ROR1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ROR1 Human Pre-designed siRNA Set A contains three designed siRNAs for ROR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ROR1 Human Pre-designed siRNA Set A ROR1 Human Pre-designed siRNA Set A

HY-P992376

huXBR1-402 NBE-002 Antibody	ROR	Cancer
huXBR1-402 (NBE-002 Antibody) is a high-affinity (K_d=5.8 nM) humanized chimeric rabbit/human monoclonal antibody that targets *ROR1. huXBR1-402 specifically binds to the Ig/Fz domain epitope of human* ROR1, directly inhibits the proliferation of ROR1-positive tumor cells and induces apoptosis of leukemia cells (apoptosis) .

HY-P992337

CS5001 Antibody	ROR	Cancer
CS5001 Antibody is an IgG1 human monoclonal antibody targeting *ROR1. CS5001 Antibody can be used for the synthesis of the ADC CS5001. It is applicable to research related to advanced solid tumors and lymphomas. The recommended isotype control is human* IgG1 kappa (HY-P99001) .

HY-170996

ROR1 ligand-1	Ligands for Target Protein for PROTAC ROR	Cancer
ROR1 ligand-1 is a ROR1 ligand that can be used for synthesis of PROTACT ROR1 degrader-1 (HY-170995) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992376

huXBR1-402 NBE-002 Antibody	ROR	Cancer
huXBR1-402 (NBE-002 Antibody) is a high-affinity (K_d=5.8 nM) humanized chimeric rabbit/human monoclonal antibody that targets *ROR1. huXBR1-402 specifically binds to the Ig/Fz domain epitope of human* ROR1, directly inhibits the proliferation of ROR1-positive tumor cells and induces apoptosis of leukemia cells (apoptosis) .

HY-P992337

CS5001 Antibody	ROR	Cancer
CS5001 Antibody is an IgG1 human monoclonal antibody targeting *ROR1. CS5001 Antibody can be used for the synthesis of the ADC CS5001. It is applicable to research related to advanced solid tumors and lymphomas. The recommended isotype control is human* IgG1 kappa (HY-P99001) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-135319

Strictinin	Structural Classification Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Source Classification Theaceae	Bacterial Antibiotic ERK JNK NF-κB ROR Apoptosis Caspase GSK-3 Akt PI3K
Strictinin is an orally active phenolic compound. Strictinin reduces xanthine oxidase activity, uric acid production, and the activation of ERK1/2, JNK, NF-κB, and NLRP3 inflammasome components in hepatocytes treated with Xanthine (HY-W017389). Strictinin decreases elevated serum uric acid levels and enhanced xanthine oxidase activity in mice treated with potassium oxonate. Strictinin acts as a *ROR1* inhibitor and exhibits anticancer activity against highly aggressive non-androgen-dependent prostate cancer. Strictinin induces cancer cell apoptosis (apoptosis), arrests cell cycle, and inhibits cancer cell migration, invasion, and epithelial-mesenchymal transition. Strictinin modulates gut microbiota, inhibits bacterial growth and biofilm formation, accelerates small intestinal transit, and blocks viral entry and replication. Strictinin can be used in research related to hyperuricemia, androgen receptor-negative non-androgen-dependent prostate cancer, triple-negative breast cancer, bacterial infections, constipation, coronavirus infections, dental caries, and infections caused by influenza A, influenza B, and human parainfluenza virus type 1 .

Species:	Human (16)
Tag:	His (10) Tag Free (1) Avi (4) GST (2) Fc (4)
Source:	HEK293 (12) sf9 insect cells (2) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73390

	ROR1 Protein, Human (sf9, His) Inactive tyrosine-protein kinase transmembrane receptor ROR1; ROR1; NTRKR1	Human	Sf9 insect cells
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (sf9, His) is the recombinant human-derived ROR1 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P78816

	ROR1 Protein, Human (Biotinylated, HEK293, Avi) ROR1; NTRKR1	Human	HEK293
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (Biotinylated, HEK293, Avi) is the recombinant human-derived ROR1 protein, expressed by HEK293 , with C-Avi labeled tag.

HY-P78815

	ROR1 Protein, Human (Biotinylated, HEK293, Fc-Avi) ROR1; NTRKR1	Human	HEK293
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived ROR1 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag.

HY-P78510

	ROR1 Protein, Human (HEK293, His-Avi) ROR1; NTRKR1; dJ537F10.1	Human	HEK293
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived ROR1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P70732

	ROR1 Protein, Human (HEK293, His) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	HEK293
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (HEK293, His) is the recombinant human-derived ROR1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P704862

	ROR1 Protein, Human (HEK293, mFc) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	HEK293

HY-P704871

	ROR1 Protein, Human (HEK293, Fc) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	HEK293

HY-P704863

	*FITC-Labeled ROR1* Protein, Human (HEK293, His)** Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	HEK293

HY-P704864

	*FITC-Labeled ROR1* Protein, Human (HEK293, Fc)** Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	HEK293

HY-P705877

	ROR1 Protein, Human (sf9) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Ig-like domain; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	sf9 insect cells

HY-P706015

	ROR1 Protein, Human (Active, sf9, His-GST) ROR1; NTRKR1; Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1	Human	Sf9 insect cells

HY-P704868

	ROR1 Protein, Human (141a.a, HEK293, His) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Frizzled domain; Neurotrophic tyrosine kinase; receptor-related 1; ROR1; NTRKR1	Human	HEK293

HY-P704869

	ROR1 Protein, Human (88a.a, HEK293, His) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Kringle domain; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	HEK293

HY-P705878

	ROR1 Protein, Human (Inactive, sf9, His-GST) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Ig-like domain; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	sf9 insect cells

HY-P704870

	ROR1 Protein, Human (113a.a, HEK293, His) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Ig-like domain; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1	Human	HEK293

HY-P72410

	ROR1 Protein, Human (Biotinylated, HEK293, His-Avi) Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophictyrosine kinase, receptor-related 1; NTRKR1	Human	HEK293
	ROR1 protein's minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived ROR1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.

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Cat. No.	Product Name		Classification

HY-RS12124

ROR1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ROR1 Human Pre-designed siRNA Set A contains three designed siRNAs for ROR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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human ROR1

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