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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
160 Results for "
human lung carcinoma
" in MedChemExpress (MCE) Product Catalog:
Products (160)
160 Results for "human lung carcinoma" in MCE Product Catalog:
17
Ralimetinib is an ATP-competitive p38α and p38β MAPK inhibitor with an IC50 of 5.3 nmol/L against human p38α and an IC50 of 3.2 nmol/L against human p38β. Ralimetinib slows tumor growth in preclinical in vivo cancer models, exhibits oral bioavailability in mice, and achieves sustained target inhibition for 4 to 8 h. Ralimetinib is applicable for research on melanoma, non-small cell lung cancer, ovarian cancer, glioma, multiple myeloma, breast cancer, renal cancer, and head and neck squamous cell carcinoma .
16
Target:
Research Areas:
Indisulam (E 7070) is a carbonic anhydrase inhibitor and RBM39 molecular glue degrader, with Ki values of 31, 15, and 24 nM against human carbonic anhydrase I, II, and IX, respectively, and a Ki value of 65 nM against bovine carbonic anhydrase IV. Indisulam promotes the recruitment of RBM39 to the CUL4-DCAF15 E3 ubiquitin ligase complex, triggering polyubiquitination and proteasomal degradation of RBM39. Indisulam induces aberrant pre-mRNA splicing, G1 cell cycle arrest, and cell death in cancer cells. As an anticancer agent, Indisulam drives tumor regression and growth inhibition in xenograft models. Indisulam can be used in research related to solid tumors, hematologic and lymphoid malignancies, colorectal cancer, and non-small cell lung cancer .
7
7 Cited Publications
Cat. No.: HY-P7224
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; lung Giant Cell carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; Neutrophil-Activating Peptide 1; MONAP; T-Cell Chemotactic Factor; GCP-1; Interleukin 8; Monocyte-Derived Neutrophil Chemotactic Factor; Interleukin-8; Monocyte-Derived Neutrophil-Activating Peptide; Emoctakin; Granulocyte Chemotactic Protein 1; AMCF-I; Chemokine (C-X-C Motif) Ligand 8; B-ENAP; SCYB8; TSG-1; LYNAP; 3-10C; LUCT; K60; LECT; Small Inducible Cytokine Subfamily B, Member 8; IL-8; Beta-Thromboglobulin-Like Protein; GCP1; Neutrophil-Activating Protein 1; NAP1; C-X-C Motif Chemokine 8; NAF; C-X-C Motif Chemokine; Beta Endothelial Cell-Derived Neutrophil Activating Peptide; Protein 3-10C; C-X-C Motif Chemokine Ligand 8; Lymphocyte Derived Neutrophil Activating Peptide
Species:
Human
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P70569
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; lung Giant Cell carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; Neutrophil-Activating Peptide 1; MONAP; T-Cell Chemotactic Factor; GCP-1; Interleukin 8
Species:
Human
Source:
HEK293
4
4 Cited Publications
Cat. No.: HY-P1408
CAS No.: 404882-00-4
3
3 Cited Publications
Cat. No.: HY-P7379
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; lung Giant Cell carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; Neutrophil-Activating Peptide 1; MONAP; T-Cell Chemotactic Factor; GCP-1; Interleukin 8
Species:
Human
Source:
CHO
2
2 Cited Publications
Synonyms: Anti-dynamin II
Target:
Research Areas:
DYn-2 (Anti-dynamin II) is a chemoselective sulfenylated protein probe. DYn-2 binds to sulfenylated proteins with chemoselectivity, enabling the detection of such proteins. DYn-2 can detect differences in intracellular sulfenylation rates. DYn-2 can be used in human cancer research, including studies on breast cancer and lung cancer .
1
Research Areas:
Tubulysin A (TubA) is an anticancer and antiangiogenic agent with anti-microtubule, anti-mitosis and anti-proliferative activity against a variety of cancer cells with IC50 values in the pmol range. It can induce apoptosis of cancer cells and has no effect on normal cells. Tubulysins are a group of potent cytotoxins consisting of nine members (A-I). Tubulysin A can synthesize ADC as ADC Cytotoxin .
1
1
1 Cited Publications
Cat. No.: HY-P70809
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD24; Signal Transducer CD24; CD24 Molecule; Small Cell lung carcinoma Cluster 4 Antigen; CD24A; CD24 Antigen; CD24 Antigen (Small Cell lung carcinoma Cluster 4 Antigen)
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70411
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HYAL1; Hyaluronoglucosaminidase-1; Hyaluronidase 1; Tumor Suppressor LUCA-1; LUCA1; Plasma Hyaluronidase; HYAL-1; Hyaluronidase; Hyaluronoglucosaminidase 1; Hyal-1; lung carcinoma Protein 1; MPS9; Hyaluronidase-1; NAT6; LuCa-1
Species:
Human
Source:
HEK293
1
Target:
Research Areas:
Sialyl Lewis A (SLeA) sodium is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A sodium promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A sodium shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A sodium can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
Cat. No.: HY-177439
Research Areas:
HLX43 is an antibody-drug conjugate (ADC) targeting PD-L1. HLX43 consists of a human monoclonal antibody anti-PD-L1 antibody Opucolimab (HY-P99785) with the drug-linker conjugate being DL-01 (HY-155870A). HLX43 exerts superior anticancer efficacy with safety profile in vivo. HLX43 can be used for non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), esophageal squamous cell carcinoma (ESCC), melanoma (MEL), ovarian cancer (Ovc) research .
Cat. No.: HY-P10375
CAS No.: 1629665-96-8
Target:
Research Areas:
Category:
Target:
Synonyms: H-Glu-Trp-OH; L-Glutamyl-L-tryptophan
Category:
Cardiovascular Disease Animals Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-P99296
CAS No.: 725735-28-4
Synonyms: CNTO 95; Anti-human CD51 Recombinant Antibody
Cat. No.: HY-N2135
CAS No.: 114240-18-5
Category:
other families Flavonoids Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Isoflavones
Target:
MS934 is a novel improved VHL-recruiting MEK 1/2 PROTAC degrader. MS934 also degrades CRAF. MS934 can be used for the research of variety of human cancers, such as melanoma, nonsmall cell lung cancer (NSCLC), colorectal cancer, primary brain tumors, and hepatocellular carcinoma .
Cat. No.: HY-116038
CAS No.: 21688-61-9
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
