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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
human myeloperoxidase
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "human myeloperoxidase" in MCE Product Catalog:
14
14 Publications Verification
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AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat.
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Sodium 2-mercaptoethanesulfonate (Mesnum) is a thiol-containing urinary tract protective agent and aldehyde scavenger that detoxifies acrolein via its thiol group to form an inert thioether excreted in urine, and competitively inhibits human myeloperoxidase, thereby mitigating Cyclophosphamide (HY-17420)-induced cytogenetic damage. Sodium 2-mercaptoethanesulfonate can be used for research on hemorrhagic cystitis .
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Myeloperoxidase, human white blood cells (MPO) is a peroxidase. In Myeloperoxidase, human white blood cells mediate oxidative stress by promoting the production of reactive oxygen species (ROS) and active nitrogen (RNS), regulating the polarization and inflammation-related signaling pathways of microglia and neutrophils. Myeloperoxidase, human white blood cells has antibacterial activity .
Cat. No.: HY-125859E
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Myeloperoxidase, Human Neutrophil is a peroxidase. Myeloperoxidase, Human Neutrophil is a potent antibacterial agent by catalyzing the H2O2-dependent oxidation of chloride anion to generate hypochlorous acid. Myeloperoxidase, Human Neutrophil catalyzes the degradation of N-retinyl-idene-N-retinylethanolamine, a toxic form of retinal lipofuscin. Myeloperoxidase, Human Neutrophil also triggers lysosomal stress and cell death. Myeloperoxidase, Human Neutrophil can be used for the researches of inflammation and infection .
Cat. No.: HY-107665
CAS No.: 62645-28-7
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Ro 106-9920 is an orally active NF-κB inhibitor. Ro 106-9920 prevents ubiquitination of IκBα, blocks nuclear translocation of NF-κB, and inhibits NF-κB activation. Ro 106-9920 suppresses TNF-α-induced tissue factor expression and procoagulant activity, enhances TNF-α-mediated cytotoxicity against cancer cells, and eliminates the formation of neutrophil extracellular traps. Ro 106-9920 inhibits NLRP3 inflammasome activation, reduces inflammatory cytokine secretion, decreases myeloperoxidase activity, attenuates renal cell apoptosis, and improves renal function. Ro 106-9920 blocks ANG II (Angiotensin II human) (HY-13948)-induced nuclear localization of p65, internalization of AT1A receptor, colocalization of β-arrestin-2, and expression of COX-2, and alters the formation of β-arrestin endosomes. Ro 106-9920 can be used in research related to non-small cell lung cancer, acute kidney injury, diabetes mellitus, and osteoporosis .
Cat. No.: HY-W041171S
CAS No.: 857665-72-6
Cat. No.: HY-E71006
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Myeloperoxidase Isoform A, Human (EC 1.11.1.7) is a peroxidase. Myeloperoxidase is most abundantly expressed in neutrophils (a subtype of leukocytes) and produces hypohalous acid to exert its antibacterial activity.
Cat. No.: HY-E71007
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Myeloperoxidase Isoform B, Human (EC 1.11.1.7) is a peroxidase. Myeloperoxidase is most abundantly expressed in neutrophils (a subtype of leukocytes) and produces hypohalous acid to exert its antibacterial activity.
Cat. No.: HY-E71008
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Myeloperoxidase Isoform C, Human (EC 1.11.1.7) is a peroxidase. Myeloperoxidase is most abundantly expressed in neutrophils (a subtype of leukocytes) and produces hypohalous acid to exert its antibacterial activity.
Synonyms: β-Mercaptoethanesulfonic acid (ampule, 3.0 M±0.1 M in H2O)
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2-Mercaptoethanesulfonic acid (ampule, 3.0 M±0.1 M in H2O) (β-Mercaptoethanesulfonic acid (ampule, 3.0 M±0.1 M in H2O)) is a thiol-containing urinary tract protective agent and aldehyde scavenger that detoxifies acrolein via its thiol group to form an inert thioether excreted in urine, and competitively inhibits human myeloperoxidase, thereby mitigating Cyclophosphamide (HY-17420)-induced cytogenetic damage. 2-Mercaptoethanesulfonic acid can be used for research on hemorrhagic cystitis .
Cat. No.: HY-P85882
Synonyms: 84 kDa myeloperoxidase antibody; 89 kDa myeloperoxidase antibody; EC1.11.2.2 antibody; fj80f04 antibody; MPO antibody; mpx antibody; myeloid-specific peroxidase antibody; myeloperoxidase antibody; myeloperoxidase heavy chain antibody; myeloperoxidase light chain antibody; PERM_human antibody; wu:fj80f04 antibody
Cat. No.: HY-126017
CAS No.: 2411643-58-6
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Aminopyridine 2 is an irreversible, selective, and orally active myeloperoxidase (MPO) inhibitor, with an IC50 of 0.16 μM and a Ki of 24 μM against human MPO. Aminopyridine 2 is applicable to research on chronic inflammatory diseases .
Cat. No.: HY-111341R
CAS No.: 618913-30-7
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AZD5904 (Standard) is the analytical standard of AZD5904 (HY-111341). This product is intended for research and analytical applications. AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat.
Cat. No.: HY-186046
CAS No.: 2922402-01-3
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MPO-IN-10 is an orally active, selective, and irreversible inhibitor of myeloperoxidase (MPO), with an IC50 of 0.080 μM against human MPO. MPO-IN-10 exhibits higher selectivity for extracellular MPO over intracellular (neutrophil) MPO. MPO-IN-10 can be used in the study of inflammatory diseases such as vascular disorders .
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Alkaline phosphatase (Apase), Human (HEK293) is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase improves survival rate of mice infected with E. coli. Alkaline phosphatase improves TNBS-induced colon inflammation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
