Ro 106-9920
Based on 2 publication(s) in Google Scholar
Ro 106-9920 is a potent inhibitor of NF-kappaB. Ro 106-9920 has the potential for the research of tumor and cancer diseases.
For research use only. We do not sell to patients.
- CAS No.: 62645-28-7
- Formula: C10H7N5OS
- Molecular Weight:245.26
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Ro 106-9920
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Biological Activity
NF-kappaB[1]
Chemical Information
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CAS No. 62645-28-7
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Appearance Solid
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Molecular Weight 245.26
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Formula C10H7N5OS
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Color White to off-white
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SMILES
O=S(C1=CC=CC=C1)C2=NN3N=NN=C3C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Front Biosci (Landmark Ed)
Neutrophil Extracellular Trap Formation Suppressed by Ro 106-9920 Enhances Diabetic Wound Healing by Blocking NLRP3 Inflammasome Activation. [Abstract]2025 May 19;30(5):37393. PMID: 40464514 -
Ren Fail
Suppression of nF-κB by ro 106-9920 alleviates ischemia/reperfusion-induced renal dysfunction and inflammation via modulation of neutrophil extracellular trap formation in acute kidney injury mice. [Abstract]2025 Dec;47(1):2545983. PMID: 40796802
Solvent & Solubility
DMSO : 20 mg/mL (81.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.0773 mL | 20.3865 mL | 40.7731 mL | 101.9326 mL |
| 5 mM | 0.8155 mL | 4.0773 mL | 8.1546 mL | 20.3865 mL | |
| 10 mM | 0.4077 mL | 2.0387 mL | 4.0773 mL | 10.1933 mL | |
| 15 mM | 0.2718 mL | 1.3591 mL | 2.7182 mL | 6.7955 mL | |
| 20 mM | 0.2039 mL | 1.0193 mL | 2.0387 mL | 5.0966 mL | |
| 25 mM | 0.1631 mL | 0.8155 mL | 1.6309 mL | 4.0773 mL | |
| 30 mM | 0.1359 mL | 0.6796 mL | 1.3591 mL | 3.3978 mL | |
| 40 mM | 0.1019 mL | 0.5097 mL | 1.0193 mL | 2.5483 mL | |
| 50 mM | 0.0815 mL | 0.4077 mL | 0.8155 mL | 2.0387 mL | |
| 60 mM | 0.0680 mL | 0.3398 mL | 0.6796 mL | 1.6989 mL | |
| 80 mM | 0.0510 mL | 0.2548 mL | 0.5097 mL | 1.2742 mL |
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