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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
immunoglobulin G1 (IgG1)
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "immunoglobulin G1 (IgG1)" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P99033
CAS No.: 1905409-39-3
Synonyms: BTCT-4465A; RG-7828; RO7030816
Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs). The Fc region of Mosunetuzumab incorporates a "knob-into-hole" structural modification and an N297G point mutation to achieve heterodimerization and eliminate Fc glycosylation, thereby effectively silencing antibody effector functions .
1
1 Cited Publications
Cat. No.: HY-P73143
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P73901
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70796
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
Cat. No.: HY-P99955
CAS No.: 2431972-52-8
Synonyms: AMG 451; KHK4083
Target:
Research Areas:
Cat. No.: HY-P99036
CAS No.: 1296818-77-3
Synonyms: REGN910
Target:
Research Areas:
Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1. Nesvacumab can be used in vascular researches .
Cat. No.: HY-P99157
CAS No.: 1895083-75-6
Synonyms: Mab 8H9
Target:
Research Areas:
Omburtamab (Mab 8H9) is a mouse monoclonal immunoglobulin G1 (IgG1) antibody targeting B7-H3. Omburtamab specifically binds to the glycoprotein antigen B7-H3, which is widely expressed on the surface of tumor cells. As a targeting carrier for recombinant toxins, it delivers PE38 to inhibit cellular protein synthesis and induce cytotoxicity in antigen-expressing cancer cells. Omburtamab can be used in research related to glioma, breast cancer, osteosarcoma and neuroblastoma .
Cat. No.: HY-P99551
CAS No.: 1374419-41-6
Synonyms: KBSA301; AR-301
Target:
Research Areas:
Cat. No.: HY-P991678
CAS No.: 2996895-52-2
Synonyms: XENP-27564; XMAB-27564
Target:
Research Areas:
Cat. No.: HY-P991195
Synonyms: SIM1811-03
Target:
Research Areas:
SIM-0235 is humanized immunoglobulin G1 (IgG1) monoclonal antibody that targets and inhibits TNFR2, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) [1].
Cat. No.: HY-P991158
CAS No.: 2996105-98-5
Target:
Research Areas:
Cat. No.: HY-P72379
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
Cat. No.: HY-P73903
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
CHO
Cat. No.: HY-P704685
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
Cat. No.: HY-P704686
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
Cat. No.: HY-P705033
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
Cat. No.: HY-P77526
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
Cat. No.: HY-P78670
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
Cat. No.: HY-P78671
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
Cat. No.: HY-P70796A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
