Search Result
Results for "
inert
" in MedChemExpress (MCE) Product Catalog:
11
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-D0227
-
THAM
1 Publications Verification
Tris; Tris(hydroxymethyl)aminomethane
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Biochemical Assay Reagents
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Metabolic Disease
|
|
THAM (Tris) is a low-toxicity amino alcohol buffer, a specific CO2-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM binds protons to form bicarbonate, reduces PaCO2, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM may cause PaCO2 rebound, hypoglycemia, and respiratory depression. THAM removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM can act as a CO2 carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications .
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- HY-111373
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RapaLink-1
Maximum Cited Publications
13 Publications Verification
|
mTOR
Autophagy
|
Cancer
|
|
RapaLink-1, the third-generation bivalent mTOR inhibitor, combines Rapamycin (HY-10219) with MLN0128 (HY-13328, a second-generation mTOR kinase inhibitor) by an inert chemical linker. RapaLink-1 shows better efficacy than Rapamycin or mTOR kinase inhibitors (TORKi), potently blocking cancer-derived, activating mutants of mTOR. RapaLink-1 can cross the blood-brain barrier. RapaLink-1 binding to FKBP12 results in targeted and durable inhibition of mTORC1. RapaLink-1 plays an antithrombotic role in antiphospholipid syndrome by improving autophagy. Anticancer activity .
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- HY-112624B
-
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Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
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Bacterial
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Others
|
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Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
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- HY-D0227A
-
|
Tris HCl; Tris(hydroxymethyl)aminomethane hydrochloride
|
Biochemical Assay Reagents
|
Metabolic Disease
Cancer
|
|
THAM hydrochloride (Tris HCl) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM hydrochloride is an effective amine compound for pH control in the physiological range .
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- HY-W096178B
-
|
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Biochemical Assay Reagents
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Others
|
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Silica sand, 1-2 mm is an inorganic, inert, and biocompatible (under certain conditions) solid matrix composed of high-purity silica particles. Silica sand, 1-2 mm is primarily used as a physical functional material in biochemical research .
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- HY-W127717
-
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Perfluoro-compound FC-40
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Biochemical Assay Reagents
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Others
|
|
Fluorinert FC-40 is a non-conductive liquid containing a mixture of fluorinated compounds. It is commonly used as a cooling and heat transfer fluid in electronics, especially in high-performance computer systems and electronic components that generate a lot of heat. Fluorinert FC-40 has various properties that make it ideal for these applications, including its low viscosity, high thermal stability and excellent dielectric strength. In addition, it can be used as an inert solvent in chemical reactions and a lubricant in mechanical systems.
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-
-
- HY-P99572
-
|
BNT-312; DuoBody-CD40x-4-1BB; GEN1042
|
TNF Receptor
|
Inflammation/Immunology
Cancer
|
|
Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity .
|
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- HY-Y1219H
-
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Biochemical Assay Reagents
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Others
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Silica gel, high-purity grade, 200-400 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
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- HY-104035E
-
|
Poly(dimethylsiloxane) (PDMS), viscosity 100 cSt (25 °C); Dimethylsilcone fluid, viscosity 100 cSt (25 °C)
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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Dimethyl silicone oil, viscosity 100 cSt (25 °C) (Poly(dimethylsiloxane) (PDMS), viscosity 100 cSt (25 °C); Dimethylsilcone fluid, viscosity 100 cSt (25 °C)) is a transparent, colorless, and inert polydimethylsiloxane liquid with stable properties. Dimethyl silicone oil, viscosity 100 cSt (25 °C) exhibits high dielectric strength and excellent lubrication, cushioning, and thermal conductivity. Dimethyl silicone oil, viscosity 100 cSt (25 °C) can be used in cosmetics, lubricants, and electronics.
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- HY-16215
-
|
G-202
|
Peptide-Drug Conjugates (PDCs)
PSMA
Calcium Channel
|
Cancer
|
|
Mipsagargin (G-202) is a novel thapsigargin-based targeted proagent consisting of a prostate-specific membrane antigen (PSMA)-specific peptide coupled to an analog of the potent sarcoplasmic/endoplasmic reticulum calcium adenosine triphosphatase (SERCA) pump inhibitor Thapsigargin (HY-13433). Mipsagargin is activated by PSMA-mediated cleavage of an inert masking peptide. Mipsagargin has the potential for refractory, advanced or metastatic solid tumours research .
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- HY-W393372
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-
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- HY-107520
-
|
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Drug Derivative
|
Neurological Disease
|
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MNI-caged-L-glutamate is an inert photolabile glutamate precursor. MNI-caged-L-glutamate does not modulate NMDA and AMPA receptor function in cultured neurones. MNI-caged-L-glutamate can be used for research on neurotransmitters .
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- HY-Y1219E
-
|
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Biochemical Assay Reagents
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Others
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Silica gel, high-purity grade, 130-270 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
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- HY-W096178C
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Biochemical Assay Reagents
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Others
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Silica sand, 2-7 mm is an inorganic, inert, and biocompatible (under certain conditions) solid matrix composed of high-purity silica particles. Silica sand, 2-7 mm is primarily used as a physical functional material in biochemical research .
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- HY-Y1219I
-
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Biochemical Assay Reagents
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Others
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Silica gel, high-purity grade, 70-230 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
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- HY-Y1219D
-
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Biochemical Assay Reagents
|
Others
|
|
Silica gel, high-purity grade, 35-70 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
|
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- HY-Y1219C
-
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Biochemical Assay Reagents
|
Others
|
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Silica gel, high-purity grade, 220-440 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
|
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- HY-131039
-
|
MDNI-glu
|
Amino Acid Derivatives
|
Others
|
|
MDNI-caged-L-glutamate (MDNI-glu) is a biologically inert, photosensitive derivative of the major excitatory amino acid, L-glutamate. MDNI-caged-L-glutamate makes more efficient use of incident light .
|
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- HY-D0227R
-
|
Tris (Standard); Tris(hydroxymethyl)aminomethane (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Metabolic Disease
Cancer
|
|
THAM (Standard) is the analytical standard of THAM. This product is intended for research and analytical applications. THAM (Tris) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM is an effective amine compound for pH control in the physiological range .
|
-
-
- HY-133105
-
|
Oxothiazolidinecarboxylic acid
|
Drug Intermediate
|
Inflammation/Immunology
|
|
Procysteine, an antioxidant, is a proagent of cysteine that is inert until metabolized to cysteine intracellulary, thus stimulating glutathione synthesis .
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-
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- HY-D0227AR
-
|
Tris HCl (Standard); Tris(hydroxymethyl)aminomethane hydrochloride (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Metabolic Disease
Cancer
|
|
THAM (hydrochloride) (Standard) is the analytical standard of THAM (hydrochloride). This product is intended for research and analytical applications. THAM hydrochloride (Tris HCl) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM hydrochloride is an effective amine compound for pH control in the physiological range .
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- HY-107520A
-
|
|
Drug Derivative
|
Neurological Disease
|
|
MNI-caged-L-glutamate TFA is an inert photolabile glutamate precursor. MNI-caged-L-glutamate TFA does not modulate NMDA and AMPA receptor function in cultured neurones. MNI-caged-L-glutamate TFA can be used for research on neurotransmitters .
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- HY-158918
-
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4-CF3-Triphenylphosphonium-DC
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Biochemical Assay Reagents
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Others
|
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4-CF3-TPP-DC (4-CF3-Triphenylphosphonium-DC) is an inert mitochondrial targeting carrier, that delivers target drugs and probes to mitochondria without causing mitochondrial depolarization and cytotoxicity in cell C2C12 .
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- HY-W591314
-
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Biochemical Assay Reagents
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Others
|
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m-PEG11-Ms is a PEG linker featuring a methoxy cap and a mesylate group. The methoxy cap is inert while the mesylate is a good leaving group which is easily displaced by nucleophiles such as alcohols and amines.
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- HY-E71182
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Biochemical Assay Reagents
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Others
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11β-Hydroxysteroid dehydrogenase (EC 1.1.1.146) catalyze the conversion of inert 11 keto-products (cortisone) to active cortisol, or vice versa, thus regulating the access of glucocorticoids to the steroid receptors.
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- HY-P992370
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Interleukin Related
IFNAR
|
Cancer
|
|
HPN601 is a protease-activated EpCAM-targeting T-cell engager that binds EpCAM competitively and induces T-cell mediated tumor cell killing. HPN601 binds to EpCAM, CD3e and albumin; albumin binding extends its half-life, while masking groups keep the molecule inert outside the tumor microenvironment. HPN601 significantly reduces the release levels of IFN-γ, IL-2, IL-6 and IL-10. HPN601 can be used in research related to cancers such as breast cancer and gastric cancer .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-112624B
-
|
Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
|
Biochemical Assay Reagents
|
|
Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
|
-
- HY-W096178B
-
|
|
Biochemical Assay Reagents
|
|
Silica sand, 1-2 mm is an inorganic, inert, and biocompatible (under certain conditions) solid matrix composed of high-purity silica particles. Silica sand, 1-2 mm is primarily used as a physical functional material in biochemical research .
|
-
- HY-W127717
-
|
Perfluoro-compound FC-40
|
Biochemical Assay Reagents
|
|
Fluorinert FC-40 is a non-conductive liquid containing a mixture of fluorinated compounds. It is commonly used as a cooling and heat transfer fluid in electronics, especially in high-performance computer systems and electronic components that generate a lot of heat. Fluorinert FC-40 has various properties that make it ideal for these applications, including its low viscosity, high thermal stability and excellent dielectric strength. In addition, it can be used as an inert solvent in chemical reactions and a lubricant in mechanical systems.
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-
- HY-Y1219H
-
|
|
Biochemical Assay Reagents
|
|
Silica gel, high-purity grade, 200-400 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
|
-
- HY-104035E
-
|
Poly(dimethylsiloxane) (PDMS), viscosity 100 cSt (25 °C); Dimethylsilcone fluid, viscosity 100 cSt (25 °C)
|
Biochemical Assay Reagents
|
|
Dimethyl silicone oil, viscosity 100 cSt (25 °C) (Poly(dimethylsiloxane) (PDMS), viscosity 100 cSt (25 °C); Dimethylsilcone fluid, viscosity 100 cSt (25 °C)) is a transparent, colorless, and inert polydimethylsiloxane liquid with stable properties. Dimethyl silicone oil, viscosity 100 cSt (25 °C) exhibits high dielectric strength and excellent lubrication, cushioning, and thermal conductivity. Dimethyl silicone oil, viscosity 100 cSt (25 °C) can be used in cosmetics, lubricants, and electronics.
|
-
- HY-W393372
-
|
Tris maleate; Tris(hydroxymethyl)aminomethane maleate
|
Biochemical Assay Reagents
|
|
THAM (Tris) maleate is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM maleate is an effective amine compound for pH control in the physiological range .
|
-
- HY-Y1219E
-
|
|
Biochemical Assay Reagents
|
|
Silica gel, high-purity grade, 130-270 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
|
-
- HY-W096178C
-
|
|
Biochemical Assay Reagents
|
|
Silica sand, 2-7 mm is an inorganic, inert, and biocompatible (under certain conditions) solid matrix composed of high-purity silica particles. Silica sand, 2-7 mm is primarily used as a physical functional material in biochemical research .
|
-
- HY-Y1219I
-
|
|
Biochemical Assay Reagents
|
|
Silica gel, high-purity grade, 70-230 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
|
-
- HY-Y1219D
-
|
|
Biochemical Assay Reagents
|
|
Silica gel, high-purity grade, 35-70 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
|
-
- HY-Y1219C
-
|
|
Biochemical Assay Reagents
|
|
Silica gel, high-purity grade, 220-440 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-16215
-
|
G-202
|
Peptide-Drug Conjugates (PDCs)
PSMA
Calcium Channel
|
Cancer
|
|
Mipsagargin (G-202) is a novel thapsigargin-based targeted proagent consisting of a prostate-specific membrane antigen (PSMA)-specific peptide coupled to an analog of the potent sarcoplasmic/endoplasmic reticulum calcium adenosine triphosphatase (SERCA) pump inhibitor Thapsigargin (HY-13433). Mipsagargin is activated by PSMA-mediated cleavage of an inert masking peptide. Mipsagargin has the potential for refractory, advanced or metastatic solid tumours research .
|
| Cat. No. |
Product Name |
Target |
Research Area |
Image |
-
- HY-P99572
-
|
BNT-312; DuoBody-CD40x-4-1BB; GEN1042
|
TNF Receptor
|
Inflammation/Immunology
Cancer
|
|
Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity .
|
-
(5)
-
- HY-P992370
-
|
|
Interleukin Related
IFNAR
|
Cancer
|
|
HPN601 is a protease-activated EpCAM-targeting T-cell engager that binds EpCAM competitively and induces T-cell mediated tumor cell killing. HPN601 binds to EpCAM, CD3e and albumin; albumin binding extends its half-life, while masking groups keep the molecule inert outside the tumor microenvironment. HPN601 significantly reduces the release levels of IFN-γ, IL-2, IL-6 and IL-10. HPN601 can be used in research related to cancers such as breast cancer and gastric cancer .
|
-
(5)
| Cat. No. |
Product Name |
|
Classification |
-
- HY-112624B
-
|
Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
|
|
Polymers
|
|
Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by α-(1→6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance.
|
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