2 Results for "

levator

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "levator" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-112257
CAS No.: 1010396-29-8
Purity:  99.93%
Target:  

Androgen Receptor

Research Areas:  

Metabolic Disease

S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 induces androgen receptor (AR)-mediated transcriptional activation in CV-1 cells. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats .
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Cat. No.: HY-106391
CAS No.: 33765-68-3
Synonyms: TSAA-291
Target:  

Androgen Receptor

Research Areas:  

Endocrinology

Oxendolone (TSAA-291) is a steroidal antiandrogen with partial agonist properties, exhibiting a Ki value of 1.4 nM for the androgen receptor. Oxendolone exerts tissue-specific androgen receptor activity, induces unique androgen receptor conformational changes, and drives differential cofactor recruitment. Oxendolone is recruited to the androgen receptor in a PIAS1-dependent manner. Oxendolone increases levator ani muscle weight in castrated mice. Oxendolone can be used for research on benign prostatic hyperplasia .
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