9 Results for "

metabolite of Diclofenac

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "metabolite of Diclofenac" in MCE Product Catalog:

Cat. No.: HY-15550
CAS No.: 64118-84-9
Purity:  99.70%
4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties .
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Cat. No.: HY-15550S
CAS No.: 254762-27-1
Purity:  98.92%
4'-Hydroxy diclofenac-d4 is the deuterium labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties .
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Cat. No.: HY-126848
CAS No.: 64118-81-6
Purity:  95.6%
Synonyms: D-1-O-G
Diclofenac acyl glucuronide (D-1-O-G) is an orally active glucuronide metabolite of Diclofenac (HY-15036). Diclofenac acyl glucuronide exhibits SOD inhibitory activity, COX-1 inhibitory activity (IC50 = 0.620 μM), and COX-2 inhibitory activity (IC50 = 2.91 μM). Diclofenac acyl glucuronide induces reactive oxygen species (ROS) production and acts as a substrate of OATP2B1. Diclofenac acyl glucuronide induces small intestinal ulcers . Diclofenac acyl glucuronide can be used in research related to intestinal diseases and small intestinal ulcers .
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Cat. No.: HY-124542
CAS No.: 69002-84-2
Research Areas:  

Cancer

5-Hydroxydiclofenac is a major metabolite of Diclofenac (HY-15036). 5-Hydroxydiclofenac is formed by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C189, CYP2C19, and CYP2C8. 5-Hydroxydiclofenac shows apoptotic effects in hepatocytes .
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Cat. No.: HY-114689
CAS No.: 15307-78-5
Purity:  ≥97.0%
Target:  

Drug Metabolite

Research Areas:  

Inflammation/Immunology

Diclofenac methyl ester is a metabolite of Diclofenac (HY-15036), which exhibits acute cytotoxicity with a LC50 of 0.5 mg/L in H. azteca .
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Cat. No.: HY-15550R
CAS No.: 64118-84-9
4'-Hydroxy diclofenac (Standard) is the analytical standard of 4'-Hydroxy diclofenac. This product is intended for research and analytical applications. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties .
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Cat. No.: HY-138290
CAS No.: 698358-10-0
Target:  

Drug Intermediate

Research Areas:  

Inflammation/Immunology

Diclofenac acyl-β-D-glucuronide allyl ester is an intermediate in the synthesis of the COX inhibitor metabolite Diclofenac acyl glucuronide (HY-126848) .
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Cat. No.: HY-15550S1
CAS No.: 1189656-64-1
4'-Hydroxy diclofenac- 13C6 is the 13C labeled 4'-Hydroxy diclofenac . 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties .
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Cat. No.: HY-W739894S
Diclofenac metabolite- 13C6 is the 13C-labeled 1-(2,6-Dichloro-4-hydroxphenyl)-1,3-dihydroindol-2-one (HY-W739894).
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