Diclofenac methyl ester
Based on 1 Customer Validation
Diclofenac methyl ester is a metabolite of Diclofenac (HY-15036), which exhibits acute cytotoxicity with a LC50 of 0.5 mg/L in H. azteca.
For research use only. We do not sell to patients.
- Purity: 98.04%
- CAS No.: 15307-78-5
- Formula: C15H13Cl2NO2
- Molecular Weight:310.18
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-15037
Diclofenac Sodium
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HY-134521
Diclofenac amide
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HY-15037R
Diclofenac Sodium (Standard)
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HY-15036
Diclofenac
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HY-B0261
Meloxicam
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HY-Z6135
Aceclofenac impurity 3
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HY-119469
Aceclofenac ethyl ester
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HY-B0253
Piroxicam
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HY-14398
Celecoxib
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HY-15036R
Diclofenac (Standard)
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HY-78131A
(S)-(+)-Ibuprofen
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HY-B0261R
Meloxicam (Standard)
Biological Activity
Chemical Information
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CAS No. 15307-78-5
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Appearance Solid
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Molecular Weight 310.18
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Formula C15H13Cl2NO2
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Color Off-white to light yellow
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SMILES
O=C(CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 12.5 mg/mL (40.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2239 mL | 16.1197 mL | 32.2393 mL | 80.5984 mL |
| 5 mM | 0.6448 mL | 3.2239 mL | 6.4479 mL | 16.1197 mL | |
| 10 mM | 0.3224 mL | 1.6120 mL | 3.2239 mL | 8.0598 mL | |
| 15 mM | 0.2149 mL | 1.0746 mL | 2.1493 mL | 5.3732 mL | |
| 20 mM | 0.1612 mL | 0.8060 mL | 1.6120 mL | 4.0299 mL | |
| 25 mM | 0.1290 mL | 0.6448 mL | 1.2896 mL | 3.2239 mL | |
| 30 mM | 0.1075 mL | 0.5373 mL | 1.0746 mL | 2.6866 mL | |
| 40 mM | 0.0806 mL | 0.4030 mL | 0.8060 mL | 2.0150 mL |
Diclofenac methyl ester Related Classifications
HY-114689 Related Classifications
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