64118-84-9
64118-84-9
Chemical Structure
4'-Hydroxy diclofenac
- CAS No.: 64118-84-9
- Formula:C14H11Cl2NO3
- Molecular Weight:312.15
IUPAC Name: 2-(2-((2,6-dichloro-4-hydroxyphenyl)amino)phenyl)acetic acid
InChIKey: KGVXVPRLBMWZLG-UHFFFAOYSA-N
SMILES: O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=C(O)C=C2Cl
Biological Activity: 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
4'-Hydroxy diclofenac | 99.70% | 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4'-Hydroxy diclofenac (Standard) | ≥98% | 4'-Hydroxy diclofenac (Standard) is the analytical standard of 4'-Hydroxy diclofenac. This product is intended for research and analytical applications. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4'-Hydroxy diclofenac-d4 | 98.92% | 4'-Hydroxy diclofenac-d4 is the deuterium labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4'-Hydroxy diclofenac-13C6 | 4'-Hydroxy diclofenac-13C6 is the 13C labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. J Shimamoto, et al. Lack of Differences in Diclofenac (A Substrate for CYP2C9) Pharmacokinetics in Healthy Volunteers With Respect to the Single CYP2C9*3 Allele. Eur J Clin Pharmacol. 2000 Apr;56(1):65-8. [Content Brief]
- [2]. Hidetaka Kamimura, et al. Formation of the Accumulative Human Metabolite and Human-Specific Glutathione Conjugate of Diclofenac in TK-NOG Chimeric Mice With Humanized Livers. Drug Metab Dispos. 2015 Mar;43(3):309-16. [Content Brief]
