9 Results for "

micronuclei

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "micronuclei" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N6739
CAS No.: 26048-05-5
Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages .
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Cat. No.: HY-W683760
CAS No.: 16543-55-8
Synonyms: (2S)-N'-Nitrosonornicotine
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .
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Cat. No.: HY-N6739S
Beauvericin- 13C45 is 13C labeled Beauvericin (HY-N6739). Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages .
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Cat. No.: HY-W726392
CAS No.: 138768-62-4
Target:  

Adrenergic Receptor

Research Areas:  

Endocrinology

N-Nitrosometoprolol is an N-nitroso derivative formed by the in vitro reaction of β-adrenergic blockers with sodium nitrite. N-Nitrosometoprolol can induce micronuclei in rat liver, bone marrow and spleen .
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Cat. No.: HY-119983
CAS No.: 194-59-2
Purity:  99.98%
Synonyms: DBC
Research Areas:  

Cancer

7H-Dibenzo[c,g]carbazole (DBC) is an azaarene with high lipophilicity. 7H-Dibenzo[c,g]carbazole has carcinogenic activity and induce DNA adducts in fish, DNA adducts, mutations in diploid human fibroblasts and micronuclei in human blood lymphocytes. 7H-Dibenzo[c,g]carbazole is activated by cytochrome P450 enzymes resulting mainly in the generation of phenolic metabolites .
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Cat. No.: HY-118379
CAS No.: 156074-08-7
Target:  

Topoisomerase

Research Areas:  

Inflammation/Immunology

NU/ICRF 500 is a topo II catalytic inhibitor which increases CREST negative micronuclei in human lymphocytes .
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Cat. No.: HY-W743781
CAS No.: 1426174-36-8
Synonyms: (2S)-N'-Nitrosonornicotine-d4
N-Nitrosonornicotine-d4 ((2S)-N'-Nitrosonornicotine-d4) is deuterium labeled N-Nitrosonornicotine. N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .
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Cat. No.: HY-P5834A
Target:  

Caspase Apoptosis

Research Areas:  

Inflammation/Immunology

Boc-AEVD-CHO TFA is a Caspase 8 inhibitor. Boc-AEVD-CHO TFA significantly increases the frequencies of Nocodazole (HY-13520) or methyl methane sulfonate (MMS) induced micronuclei (MN) and micronucleated binucleates (MNCB) in PBMC by inhibiting cell apoptosis. Boc-AEVD-CHO TFA can be used for immune and inflammatory diseases research .
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Cat. No.: HY-N21728
CAS No.: 15887-38-4
4-Hydroxybenzyl-β-D-glucopyranoside is a phenolic glucoside found in the halophyte Atriplex littoralis. 4-Hydroxybenzyl-β-D-glucopyranoside is one of the components of Rhodiola injection. 4-Hydroxybenzyl-β-D-glucopyranoside exhibits radiation-mitigating activity by reducing the frequency of radiation-induced micronuclei in human lymphocytes. 4-Hydroxybenzyl-β-D-glucopyranoside can be used in research related to radiation injury and oxidative stress .
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