Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
mouse L1210
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "mouse L1210" in MCE Product Catalog:
Cat. No.: HY-10939A
CAS No.: 84937-45-1
Target:
Domaines de recherche:
(-)-15-Deoxyspergualin trihydrochloride is a potent antitumor agent. (-)-15-Deoxyspergualin trihydrochloride shows strong inhibition against mouse leukemia L-1210 .
Cat. No.: HY-W007479
CAS No.: 24677-78-9
Cat. No.: HY-10939
CAS No.: 89149-10-0
Target:
Domaines de recherche:
(-)-15-Deoxyspergualin is a potent antitumor agent. (-)-15-Deoxyspergualin shows strong inhibition against mouse leukemia L-1210 .
Cat. No.: HY-19015
CAS No.: 95604-83-4
Synonyms: AT-2153
Target:
Domaines de recherche:
Probimane (AT-2153) is a potent anticancer agent. Probimane is effective against mouse tumors S37, S180, Lewis lung carcinoma, L1210 and human pulmonary adenocarcinoma heterotransplanted into nude mice .
Cat. No.: HY-118917
CAS No.: 297730-05-3
Target:
Domaines de recherche:
VX-148 is an orally active immunosuppressant, which is a non-competitive inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor with Ki values for IMPDH Ⅱ and IMPDH Ⅰ of 6 and 14 nM respectively. VX-148 can significantly inhibit the proliferation of human peripheral blood mononuclear cells (PBMC) stimulated by T-cell mitogen (PHA) or B-cell mitogen (SPAS). VX-148 has high selectivity for lymphocytes (such as L1210, Jurkat T cells, and Raji B cells), but has no significant toxicity to non-lymphoid cells. VX-148 can inhibit antibody responses in mouse models and significantly prolong the survival time of transplanted skin in allogeneic skin transplantation models. VX-148 can be used in the research of autoimmune diseases (such as rheumatoid arthritis, psoriasis) and organ transplantation anti-rejection .
Cat. No.: HY-N8519
CAS No.: 104542-46-3
Category:
Target:
Cat. No.: HY-N14787
CAS No.: 82501-56-2
Category:
Target:
Cat. No.: HY-N14499
CAS No.: 92569-01-2
Category:
Target:
Cat. No.: HY-N14515
CAS No.: 92569-02-3
Category:
Target:
Cat. No.: HY-N14516
CAS No.: 92569-03-4
Category:
Target:
Cat. No.: HY-126170
CAS No.: 101961-60-8
Category:
Target:
Cat. No.: HY-N14747
CAS No.: 97218-42-3
Category:
Target:
Cat. No.: HY-N14144
CAS No.: 182285-29-6
Category:
Target:
Category:
Target:
Cat. No.: HY-117285
CAS No.: 60227-09-0
Synonyms: Lactoquinomycin A; LQM-A
Category:
Target:
Cat. No.: HY-N14774
CAS No.: 101342-94-3
Category:
Target:
Cat. No.: HY-N14530
CAS No.: 11050-22-9
Category:
Target:
Cat. No.: HY-119143
CAS No.: 32093-09-7
Domaines de recherche:
CB 3703 is an inhibitor of thymidylate synthase (TS) and dihydrofolate reductase (DHFR). CB 3703 has an IC50 of 0.25 μM against rat TS, a Ki of 0.47 μM against mouse TS, an IC50 of 6.8 nM against rat DHFR, and a Ki of 0.6 pM against mouse DHFR. CB 3703 is transported via the reduced folate pathway, has a short plasma half-life, and can prolong the survival of tumor-bearing mice. CB 3703 can be used in the research of L1210 ascites tumors .
Cat. No.: HY-159803
CAS No.: 128201-92-3
Synonyms: 6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin
Target:
Domaines de recherche:
IST-622 (6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin) is an anti-tumor agent with significant growth inhibitory activity. IST-622 exhibits significant anti-tumor effects against a variety of mouse tumors such as P388 and L1210 leukemias, B16 melanoma, Lewis lung carcinoma, Colon 26 and Colon 38 adenocarcinomas, and M5076 reticulum cell sarcoma. IST-622 was orally administered and the results showed efficacy in different tumor types. In addition, IST-622 provided significant inhibitory effects against two human tumor xenograft models: large cell lung carcinoma (Lu-116) and gastric adenocarcinoma (St-4). IST-622 also exhibited significant growth inhibitory activity against P388 leukemia in vitro, with a half inhibitory concentration (IC50) more than 20 times lower than CT .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
