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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
murine B16F10 melanoma cells
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "murine B16F10 melanoma cells" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-10615
CAS No.: 272769-49-0
A-620223 is a PARP-1 inhibitor with a Ki of 8 nM against PARP-1 and EC50 of 3 nM in a whole cell assay. A-620223 demonstrates good in vivo efficacy in a B16F10 subcutaneous murine melanoma model in combination with Temozolomide (TMZ) (HY-17364) and in an MX-1 breast xenograph model in combination with Cisplatin (HY-17394). A-620223 can be used for the studies of melanoma and breast cancer .
Cat. No.: HY-W272217S
CAS No.: 16416-33-4
Synonyms: n-Octacosane-d58; NSC 5549-d58
Cat. No.: HY-174830
CAS No.: 3099808-68-8
Target:
Research Areas:
GJ19 is a PD-L1 inhibitor with an IC50 of 32.06 nM. GJ19 can effectively bind to human/murine PD-L1 protein with Kd values of 171 and 290 nM, respectively. GJ19 concentration-dependently promotes HepG2 cell mortality in a co-culture model of HepG2/hPD-L1 and Jurkat T/hPD-1 cells. GJ19 effectively suppresses tumor growth in a B16-F10 melanoma mouse model. GJ19 can be used for the study of tumor immunotherapy .
Cat. No.: HY-W272217
CAS No.: 630-02-4
Synonyms: n-Octacosane; NSC 5549
Category:
Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology Cancer
Target:
Cat. No.: HY-W001939
CAS No.: 586-89-0
Cat. No.: HY-N14435
CAS No.: 141869-53-6
Category:
Target:
Cat. No.: HY-W272217R
CAS No.: 630-02-4
Synonyms: n-Octacosane (Standard); NSC 5549 (Standard)
Category:
Cat. No.: HY-120241
CAS No.: 26246-41-3
Synonyms: K 251-1
Category:
Target:
Cat. No.: HY-149523
Target:
Research Areas:
Anticancer agent 157 (compound 15) is a NO inhibitor (IC50=0.62 μg/mL) with anti-inflammatory and anticancer activities. Anticancer agent 157 can bind to iNOS (inducible NO synthase) and caspase 8, causing nuclear fragmentation and chromatin condensation, inducing apoptosis. Anticancer agent 157 inhibits HT29 colon cancer cells (IC50=2.45 μg/mL), Hep-G2 liver cancer cells (IC50=3.25 μg/mL), and B16-F10 murine melanoma cells (IC50=3.84 μg/mL) .
Cat. No.: HY-W001939R
CAS No.: 586-89-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
