4-Acetylbenzoic acid
Based on 1 Customer Validation
4-Acetylbenzoic acid is a Zn(II) complex. 4-Acetylbenzoic acid is a derivative of benzoic acid that is commonly used in chemical synthesis. 4-Acetylbenzoic acid has an IC50 of 331.3 μM in murine L929 fibroblasts and an IC50 of 176 μM in metastatic melanoma B16 F10 cell lines.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.76%
- CAS. Nr.: 586-89-0
- Formel: C9H8O3
- Molecular Weight:164.16
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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HY-Y0264
4-Hydroxybenzoic acid -
HY-Y0264R
4-Hydroxybenzoic acid (Standard) -
HY-B1008
4-Aminobenzoic acidFolate Synthesis Intermediate -
HY-W001939R
4-Acetylbenzoic acid (Standard)Derivative of Benzoic Acid -
HY-N2009
3-O-Methylgallic acidApoptosis Inducer -
HY-W002751
6-Methylsalicylic acidBuilding Block -
HY-B1008R
4-Aminobenzoic acid (Standard)Folate Synthesis Intermediate -
HY-75102
4-Boronobenzoic acidBiochemical Reagent -
HY-W013396
4-Iodobenzoic acidDimeric Crystal -
HY-W002751R
6-Methylsalicylic acid (Standard)Building Block
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16-F10 | IC50 |
176 μM
Compound: 4AcBH
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Cytotoxicity against mouse B16F10 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against mouse B16F10 cells assessed as cell viability after 72 hrs by MTT assay
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[PMID: 26774931] |
| K562 | IC50 |
<1000 μM
Compound: 4AcBH
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Cytotoxicity against human K562 cells assessed as cell viability after 72 hrs by tryphan blue assay
Cytotoxicity against human K562 cells assessed as cell viability after 72 hrs by tryphan blue assay
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[PMID: 26774931] |
| L929 | IC50 |
331.3 μM
Compound: 4AcBH
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Cytotoxicity against mouse L929 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against mouse L929 cells assessed as cell viability after 72 hrs by MTT assay
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[PMID: 26774931] |
Chemical Information
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CAS. Nr. 586-89-0
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Appearance Solid
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Molecular Weight 164.16
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Formel C9H8O3
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Color White to off-white
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SMILES
O=C(O)C1=CC=C(C(C)=O)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 200 mg/mL (1218.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 6.0916 mL | 30.4581 mL | 60.9162 mL | 152.2904 mL |
| 5 mM | 1.2183 mL | 6.0916 mL | 12.1832 mL | 30.4581 mL | |
| 10 mM | 0.6092 mL | 3.0458 mL | 6.0916 mL | 15.2290 mL | |
| 15 mM | 0.4061 mL | 2.0305 mL | 4.0611 mL | 10.1527 mL | |
| 20 mM | 0.3046 mL | 1.5229 mL | 3.0458 mL | 7.6145 mL | |
| 25 mM | 0.2437 mL | 1.2183 mL | 2.4366 mL | 6.0916 mL | |
| 30 mM | 0.2031 mL | 1.0153 mL | 2.0305 mL | 5.0763 mL | |
| 40 mM | 0.1523 mL | 0.7615 mL | 1.5229 mL | 3.8073 mL | |
| 50 mM | 0.1218 mL | 0.6092 mL | 1.2183 mL | 3.0458 mL | |
| 60 mM | 0.1015 mL | 0.5076 mL | 1.0153 mL | 2.5382 mL | |
| 80 mM | 0.0761 mL | 0.3807 mL | 0.7615 mL | 1.9036 mL | |
| 100 mM | 0.0609 mL | 0.3046 mL | 0.6092 mL | 1.5229 mL |
4-Acetylbenzoic acid Related Classifications
HY-W001939 Related Classifications
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