19 Results for "

nucleoside transport

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "nucleoside transport" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-17564
CAS No.: 3992-42-5
Synonyms: 2'-Deoxycytidine monohydrochloride; Deoxycytidine hydrochloride; NSC 83251
2'-Deoxycytidine hydrochloride (2'-Deoxycytidine monohydrochloride; NSC 83251) is an orally active nucleic acid biosynthesis enzyme inhibitor. 2'-Deoxycytidine hydrochloride competes with nucleic acid biosynthesis enzymes and nucleoside transporters, thereby reducing the toxicity of cytarabine. 2'-Deoxycytidine hydrochloride can be used in the research of L1210 lymphoblastic leukemia .
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2
2 Cited Publications
Cat. No.: HY-100957
CAS No.: 20153-98-4
Purity:  99.64%
Research Areas:  

Cardiovascular Disease

Dilazep dihydrochloride is an inhibitor of adenosine uptake. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep dihydrochloride also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides .
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2
2 Cited Publications
Cat. No.: HY-113291
CAS No.: 4754-39-6
Purity:  99.92%
5'-Deoxyadenosine is a 5'-methylthioadenosine phosphorylase substrate and deoxyadenosine. 5'-Deoxyadenosine serves as a non-metabolizable substrate for nucleoside transport assays only in cells lacking 5'-methylthioadenosine phosphorylase .
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Cat. No.: HY-159650
CAS No.: 2724937-55-5
Target:  

Adenosine Receptor

Research Areas:  

Cancer

EOS-984 is a macrocyclic diamine equilibrative nucleoside transporter 1 (ENT1) inhibitor. EOS984 inhibits ENT1 and ENT1-mediated nucleoside transport, restricting adenosine entry into cells via ENT1, thereby attenuating ATP-derived adenosine-mediated T cell immunosuppression and restoring primary human T cell proliferation. EOS984 can be used in research related to ENT1-mediated nucleoside transport, adenosine-related immunosuppression, and tumor immunity .
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Cat. No.: HY-115366
CAS No.: 112415-83-5
Purity:  98.86%
Research Areas:  

Neurological Disease

Soluflazine is a nucleoside transport inhibitor with anticonvulsant action. Soluflazine can be used as an antiepileptic agent .
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Cat. No.: HY-108322
CAS No.: 13153-27-0
Purity:  99.13%
Research Areas:  

Cardiovascular Disease

NBTGR (p-Nitrobenzylthioguanosine) is a potent inhibitor of nucleoside transport; inhibits adenosine uptake with a Ki of 70 nM.
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Cat. No.: HY-100957R
CAS No.: 20153-98-4
Dilazep (dihydrochloride) (Standard) is the analytical standard of Dilazep (dihydrochloride). This product is intended for research and analytical applications. Dilazep dihydrochloride is an inhibitor of adenosine uptake. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep dihydrochloride also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides .
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Cat. No.: HY-177059
CAS No.: 65199-10-2
Synonyms: NBMPR-P
Research Areas:  

Cancer

Nitrobenzylthioinosine 5'-monophosphate (NBMPR-P), a nucleoside analog, is a prodrug of the potent nucleoside transport inhibitor Nitro-benzylthioinosine (NBMPR) (HY-W010936). Nitrobenzylthioinosine 5'-monophosphate blocks nucleoside transport in vivo and prevents host toxicity in tumor-bearing mice administered with highdoses of Tubercidin (HY-100126) .
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Cat. No.: HY-W077242
CAS No.: 635-12-1
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

1,4-Anthraquinone is a potent anticancer agent. 1,4-Anthraquinone blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of cancer cells. 1,4-Anthraquinone can be used to research anti-leukemia .
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Cat. No.: HY-123360
CAS No.: 137694-16-7
Synonyms: BIBW22BS
Target:  

Drug Derivative

Research Areas:  

Cancer

BIBW 22 (BIBW22BS) is a dipyridamole analogue. BIBW 22 is a potent bifunctional modulator that affects p-glycoprotein and nucleoside transport in tumor cells .
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Cat. No.: HY-106841A
CAS No.: 138681-29-5
Synonyms: (-)-Draflazine; (S)-R-75231; (S)-R88021
Research Areas:  

Others

(S)-Draflazine ((-)-Draflazine) is the (S)-configuration of Draflazine (HY-106841). (S)-Draflazine is a potent blocker of nucleoside transport .
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Cat. No.: HY-U00049
CAS No.: 79467-23-5
Mioflazine is an orally active nucleoside transport inhibitor with sleep-improving activity. Mioflazine significantly improves cardiac survival after global cardiac ischemia. Mioflazine inhibits nucleoside uptake Mioflazine does not exhibit inotropic effects during induction and nursing .
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Cat. No.: HY-U00049A
CAS No.: 79467-24-6
Mioflazine dihydrochloride hydrate is a nucleoside transport inhibitor with sleep-improving activity. Mioflazine dihydrochloride hydrate helps maintain the mechanical function of the left ventricle and significantly improves the heart's recovery ability after global ischemia at new temperatures. Mioflazine dihydrochloride hydrate reduces the mitochondrial calcium content in guinea-pig .
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Cat. No.: HY-U00049B
CAS No.: 83898-67-3
Mioflazine dihydrochloride is a nucleoside transport inhibitor with sleep-improving activity. Mioflazine dihydrochloride significantly improves cardiac survival after global cardiac ischemia. Mioflazine dihydrochloride reduces the mitochondrial calcium content in guinea-pig. Mioflazine dihydrochloride does not exhibit inotropic effects during induction and nursing .
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Cat. No.: HY-116042
CAS No.: 156547-56-7
Purity:  99.72%
Target:  

Adenosine Receptor

Research Areas:  

Cardiovascular Disease

FSCPX is a potent and selective irreversible antagonist of A1 adenosine receptor (A1AR), with low nanomolar potency for binding to the A1AR. FSCPX could modify the effect of NBTI, a nucleoside transport inhibitor, by reducing the interstitial adenosine level in the guinea pig atrium .
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Cat. No.: HY-113291R
CAS No.: 4754-39-6
5'-Deoxyadenosine (Standard) is the analytical standard of 5'-Deoxyadenosine (HY-113291). This product is intended for research and analytical applications. 5'-Deoxyadenosine is a 5'-methylthioadenosine phosphorylase substrate and deoxyadenosine. 5'-Deoxyadenosine serves as a non-metabolizable substrate for nucleoside transport assays only in cells lacking 5'-methylthioadenosine phosphorylase .
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Cat. No.: HY-108322R
CAS No.: 13153-27-0
Research Areas:  

Cardiovascular Disease

NBTGR (Standard) is the analytical standard of NBTGR (HY-108322). This product is intended for research and analytical applications. NBTGR (p-Nitrobenzylthioguanosine) is a potent inhibitor of nucleoside transport; inhibits adenosine uptake with a Ki of 70 nM.
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Cat. No.: HY-100957A
CAS No.: 35898-87-4
Research Areas:  

Cardiovascular Disease

Dilazep is an inhibitor of adenosine uptake. Dilazep has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides .
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Cat. No.: HY-131920
CAS No.: 27416-86-0
Synonyms: Polyuridylic acid
Poly (U) (Polyuridylic acid) is an RNA chain that exists in a disordered extended state at room temperature and serves as a TLR7 ligand. Poly (U) produces distinguishable blocking effects when transported through α-hemolysin nanopores. Poly (U) forms a triple helix with adenosine or adenosine monophosphate, thereby significantly promoting the nucleotide bond condensation reaction between adenosine monophosphate and adenosine, while exerting minimal effects on other nucleosides. When conjugated with cationic lipids, Poly (U) specifically stimulates plasmacytoid dendritic cells to produce type I interferons .
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