35898-87-4
35898-87-4
Chemical Structure
Dilazep
- CAS No.: 35898-87-4
- Formula:C31H44N2O10
- Molecular Weight:604.69
IUPAC Name: (1,4-diazepane-1,4-diyl)bis(propane-3,1-diyl) bis(3,4,5-trimethoxybenzoate)
InChIKey: QVZCXCJXTMIDME-UHFFFAOYSA-N
SMILES: O=C(C1=CC(OC)=C(OC)C(OC)=C1)OCCCN2CCN(CCCOC(C3=CC(OC)=C(OC)C(OC)=C3)=O)CCC2
Biological Activity: Dilazep is an inhibitor of adenosine uptake. Dilazep has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides[1][2].
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Dilazep | Dilazep is an inhibitor of adenosine uptake. Dilazep has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides. | |||||||||||||||||||||
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References
- [1]. Zhang Y, et al. Dilazep potentiation of adenosine-mediated superior mesenteric arterial vasodilation. J Pharmacol Exp Ther. 1991 Sep;258(3):767-71. [Content Brief]
- [2]. Kawagoe J, et al. Effect of dilazep dihydrochloride against ischemia and reperfusion-induced disruption of blood-brain barrier in rats: a quantitative study. Naunyn Schmiedebergs Arch Pharmacol. 1992 Apr;345(4):485-8. [Content Brief]
Keywords
