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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
ornithine aminotransferase
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "ornithine aminotransferase" in MCE Product Catalog:
Category:
Infection Amino acids Plants Other Families Extract Endogenous metabolite Disease Research Fields
Target:
Synonyms: 5-FMOrn dihydrochloride
Target:
Research Areas:
5-Fluoromethylornithine dihydrochloride (5-FMOrn dihydrochloride) is an orally active and blood-brain barrier-penetrant irreversible inhibitor of ornithine aminotransferase (OAT). 5-Fluoromethylornithine dihydrochloride competes with ornithine at the OAT active site and acts as a poor substrate for ornithine decarboxylase (ODC), competitively reducing ornithine decarboxylation, elevating tissue ornithine, and thereby affecting polyamine metabolism . 5-Fluoromethylornithine dihydrochloride attenuates Thioacetamide (HY-Y0698)-induced acute liver injury-related pathological changes . 5-Fluoromethylornithine dihydrochloride is used in research on acute liver injury and hyperammonemia .
Cat. No.: HY-158309
CAS No.: 3057092-65-3
Research Areas:
hOAT-IN-1 (compound 5) is a mechanical inhibitor of human ornithine aminotransferase (hOAT). hOAT-IN-1 as a time-dependent inhibitor can form tightly bound PLP inhibitor adduct with hOAT. hOAT-IN-1 can result IN tight occupation of the active site of hOAT. hOAT-IN-1 can be used in the study of lung cell carcinoma .
Cat. No.: HY-189374
CAS No.: 3057206-96-6
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Research Areas:
OAT-IN-2 is an ornithine aminotransferase (hOAT) inhibitor. OAT-IN-2 is used in the research of hepatocellular carcinoma .
Cat. No.: HY-180706
CAS No.: 99590-80-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
