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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
pancreatic α-cell
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "pancreatic α-cell" in MCE Product Catalog:
14
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14
14 Publications Verification
Cat. No.: HY-P0082A
CAS No.: 28270-04-4
Synonyms: Glucagon hydrochloride
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2
2 Cited Publications
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BRD7389 is a specific RSK family kinase inhibitor with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively. BRD7389 is a small-molecule inducer of insulin expression in pancreatic α-cells .
Cat. No.: HY-120565
CAS No.: 1594041-84-5
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WB403 is an orally active TGR5 activator with an EC50 of 5.5 μM against human TGR5. WB403 activates TGR5 to stimulate downstream signaling pathways, promote GLP-1 secretion, improve glucose tolerance in mice with type 2 diabetes, and reduce levels of fasting blood glucose, postprandial blood glucose and HbA1c. WB403 increases pancreatic β-cell mass and restores the distribution of α-cells and β-cells in islets. WB403 is applicable to the research of type 2 diabetes .
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Glybuzole (Desaglybuzole) is an orally effective hypoglycemic agent. Glybuzole promotes insulin secretion by pancreatic β cells and inhibits glucagon secretion by pancreatic α cells. Glybuzole reduces blood glucose levels as well as arginine-stimulated plasma glucagon levels. Glybuzole can be used in diabetes-related research .
Cat. No.: HY-174557
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Human PAX6 mRNA encodes the human paired box 6 (PAX6) protein, a member of the paired box (PAX) family. PAX6 may play an important role in the development of the eye, nose, central nervous system and pancreas. It is also required for the differentiation of pancreatic islet alpha cells.
Cat. No.: HY-D3173
CAS No.: 1708978-54-4
Synonyms: TPG-456
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
