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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
protein carbonyl
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "protein carbonyl" in MCE Product Catalog:
109
Target:
Research Areas:
FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
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2 Cited Publications
Cat. No.: HY-15941
CAS No.: 27072-45-3
Synonyms: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
Synonyms: UAA crosslinker 1 hydrochloride
Target:
Research Areas:
N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride (UAA crosslinker 1 hydrochloride) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research .
Target:
Research Areas:
FITC (Fluorescein Isothiocyanate) (solution) , is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
Solvent and concentration: DMSO: 20 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
Solvent and concentration: DMSO: 20 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
Cat. No.: HY-D0099
CAS No.: 76863-28-0
Synonyms: UAA crosslinker 1
Target:
Research Areas:
N6-[(2-Azidoethoxy) carbonyl]-L-lysine (UAA crosslinker 1) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy) carbonyl]-L-lysine mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy) carbonyl]-L-lysine is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research .
Cat. No.: HY-34887
CAS No.: 24782-64-7
Target:
Research Areas:
Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM .
Cat. No.: HY-172285
CAS No.: 871514-32-8
Cat. No.: HY-D1619
CAS No.: 2695564-68-0
Cat. No.: HY-154835
CAS No.: 1513855-74-7
Target:
Research Areas:
N6-[[(4-Azidophenyl)methoxy]carbonyl]-L-lysine is an unnatural lysine analog and a substrate of the PABKRS mutant PylRS. N6-[[(4-Azidophenyl)methoxy]carbonyl]-L-lysine enables site-specific genetic integration into proteins via amber stop codon suppression; it undergoes Staudinger reduction with phosphine compounds, followed by a self-elimination reaction to release native lysine. N6-[[(4-Azidophenyl)methoxy]carbonyl]-L-lysine serves as a genetically encoded element for the temporal chemical control of protein SUMOylation and nuclear translocation in living mammalian cells, and also acts as a bioorthogonal reaction handle for bioconjugation reactions .
Cat. No.: HY-172285A
Cat. No.: HY-W679138
CAS No.: 128-03-0
Target:
Research Areas:
N,N-dimethyldithiocarbamate potassium is a ubiquitin-activating enzyme E1 inhibitor. N,N-dimethyldithiocarbamate potassium inhibits the activation of E1 and reduces the level of activated ubiquitinated E1 (ub-E1). N,N-dimethyldithiocarbamate potassium increases intracellular copper levels, enhances oxidative stress, elevates protein carbonyl levels, and upregulates the expression of HO-1 . N,N-dimethyldithiocarbamate potassium is applicable to research related to Parkinson's disease .
Cat. No.: HY-P703492
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Short-chain dehydrogenase; AM233_25210
Species:
Others
Source:
E. coli
Cat. No.: HY-W837135
CAS No.: 2803460-96-8
Target:
Research Areas:
5-Hydrazinyl thalidomide hydrochloride is a Thalidomide analogue featuring a hydrazine. PROTAC linkers are made to recruit E3 ligase for the ubiquitinylation of target proteins. The hydrazine may be used for further derivatization via reactions with various carbonyl groups.
Cat. No.: HY-P75605
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CBR3; Short Chain Dehydrogenase/Reductase Family 21C, Member 2; carbonyl Reductase 3; Epididymis Secretory protein Li 25; SDR21C2; carbonyl Reductase (NADPH) 3; Short Chain Dehydrogenase/Reductase Family 21C Member 2; carbonyl Reductase (NADPH); NADPH-Dep
Species:
Human
Source:
E. coli
Cat. No.: HY-124197S
Cat. No.: HY-P72272
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CBR1; carbonyl Reductase [NADPH] 1; Prev. CBR; Short Chain Dehydrogenase/Reductase Family 21C, Member 1; SDR21C1; 15-Hydroxyprostaglandin Dehydrogenase [NADP(+)]; Short Chain Dehydrogenase/Reductase Family 21C Member 1; Epididymis Secretory Sperm Binding protein; 20-Beta-Hydroxysteroid Dehydrogenase; 15-Hydroxyprostaglandin Dehydrogenase; NADPH-Dependent carbonyl Reductase 1; carbonyl Reductase (NADPH) 1; Alcohol Dehydrogenase [NAD(P)+] CBR1; carbonyl Reductase (NADPH); Prostaglandin-E(2) 9-Reductase; HCBR1; Prostaglandin 9-Ketoreductase; CRN; carbonyl Reductase 1; PG-9-KR
Species:
Human
Source:
P. pastoris
Cat. No.: HY-W776829
CAS No.: 53958-20-6
Cat. No.: HY-P12279
Target:
Keap1-Nrf2 α-synuclein PINK1/Parkin Autophagy Apoptosis Reactive Oxygen Species (ROS) SOD Glutathione Peroxidase Cholinesterase (ChE)
Research Areas:
MAAAHR is a neuroprotective agent. MAAAHR is isolated and purified from C-phycocyanin of Spirulina platensis. MAAAHR induces antioxidant gene expression through activating the Nrf2 signaling pathway. MAAAHR inhibits excessive Autophagy by reducing the expression of proteins such as α-Syn and Parkin. MAAAHR inhibits Apoptosis. MAAAHR scavenges excessive ROS, enhances SOD, CAT, and GSH-Px activities, and reduces protein carbonyl content. MAAAHR inhibits Acetylcholinesterase. MAAAHR protects zebrafish against MPTP (HY-15608)-induced dopaminergic neuronal and neurovascular loss and alleviates motor impairment. MAAAHR can be used for research on Parkinson's disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
